Aktuelle Ernährungsmedizin 2017; 42(03): 241-272
DOI: 10.1055/s-0037-1603274
Poster
Georg Thieme Verlag KG Stuttgart · New York

BIOELECTRICAL IMPEDANCE PHASE ANGLE IN CLINICAL PRACTICE: THE RELATIONSHIP BETWEEN NUTRITIONAL RISK SCREENING, BIOELECTRICAL IMPEDANCE ANALYSIS AND SERUM SURROGATE PARAMETERS

Autoren

  • B Knappe-Drzikova

    1   Gastroenterology and Hepatology

  • S Maasberg

    1   Gastroenterology and Hepatology

  • A Sturm

    1   Gastroenterology and Hepatology

  • B Wiedenmann

    1   Gastroenterology and Hepatology

  • A Pascher

    2   General, Visceral and Transplantation Surgery, CHARITÉ, UNIVERSITY MEDICINE BERLIN, Berlin, Germany

  • UF Pape

    1   Gastroenterology and Hepatology
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
20. Juni 2017 (online)

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Introduction:

Nutritional risk screening (NRS) is a widely accepted complex approach to evaluate nutritional (NT) status in gastroenterological (GI) patients (pts). Bioelectrical impedance analysis (BIA) is a non-invasive, easy-to-use and reproducible technique to evaluate changes in body composition.

Objectives:

Evaluation of the association between NRS, BIA, phase angle (PhA) and surrogate parameters (SP), resp. for a NT assessment in GI pts.

Methods:

Nutritional status was assessed in 611 GI pts by NRS. In addition, BMI, serum albumin and serum transferrin were determined and BIA performed. Receiver Operating Curves (ROC) were estimated to determine the optimal cut-off levels of PhA.

Results:

By screening an increased risk of malnutrition (score NRS > 3) was found in 219 pts (35.8%). Well-nourished pts (score NRS 0 – 2) – 392 (64.2%) – had a statistically higher (p < 0.001) median phase angle (5.4 °± 1.03 °) as compared with the score NRS > 3 group (4.1 °± 1.08 °). Malnutrition was significantly associated with poorer results for BMI (p < 0.01), serum albumin (34.9 ± 7.4 vs. 40.5 ± 6.3; p < 0.001), serum transferrin (186.6 ± 67.7 vs. 253.5 ± 63.2; p < 0.001) and BIA (ECM/BCM-index 1.7 ± 0.8 vs. 1.12 ± 0.3; p < 0.001). A PhA of 4.85 ° in men was 74% sensitive and 71% specific and of 4.5 ° in women was 79% sensitive and 74% specific for detecting malnutrition [ROC (for men): 0.797 ± 0.027; 95% CI 0.745-.849, p < 0.001; ROC (for women): 0.808 ± 0.026; 95% CI 0.757-.860, p < 0.001)].

Conclusion:

Malnutrition is highly prevalent in hospitalized GI-pts and is associated with distinct clinical diagnoses. The present study demonstrates that PhA is a good indicator of risk for malnutrition in GI-pts. There is a significant association between NT risk, low PhA and surrogate parameters, resp. The optimal cut-off level of PhA is helpful and practical to identify pts with malnutrition risk with the intent to limit the number of in-depth NT assessments and it can easily be included into clinical NT status evaluation and management.

Disclosure of Interest:

None declared.


Die Autoren geben an, dass kein Interessenkonflikt besteht.