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Journal of Pediatric Neurology 2017; 15(03): 115-122
DOI: 10.1055/s-0037-1602821
Review Article
Georg Thieme Verlag KG Stuttgart · New York

The Relationship between Autism Spectrum Disorder and Tourette Syndrome in Childhood: An Overview of Shared Characteristics

Renata Rizzo
1   Section of Child and Adolescent Neuropsychiatry, Department of Experimental and Clinical Medicine, University of Catania, Catania, Italy
,
Mariangela Gulisano
1   Section of Child and Adolescent Neuropsychiatry, Department of Experimental and Clinical Medicine, University of Catania, Catania, Italy
,
Carla Noemi Domini
1   Section of Child and Adolescent Neuropsychiatry, Department of Experimental and Clinical Medicine, University of Catania, Catania, Italy
,
Maria Cristina Ferro
1   Section of Child and Adolescent Neuropsychiatry, Department of Experimental and Clinical Medicine, University of Catania, Catania, Italy
,
Paolo Curatolo
2   Section of Child Neuropsychiatry, Department of Neurosciences, Tor Vergata University, Rome, Italy
› Author Affiliations
Further Information

Publication History

16 January 2017

15 February 2017

Publication Date:
02 May 2017 (online)

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Abstract

Autism spectrum disorder (ASD) and Tourette syndrome (TS) are neurodevelopmental disorders. ASD and TS are traditionally considered to be separate conditions. Nevertheless, these disorders have a high degree of overlap, and “pure” cases are rare in both clinical and population-based studies. The aim of the present review was to analyze the similarities and differences between ASD and TS on the basis of genetic and neuroradiological findings.

Keywords

Autism spectrum disorder - Tourette syndrome - comorbidity - genetics

Note

R.R. and M.G. were involved in the aripiprazole trial. Both the authors are investigators on aripiprazole trial OPD 31–12–293 and OPD 31–12–294.


 

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