Abstract
Objectives Operative time, previously identified as a risk factor for postoperative morbidity,
is examined in patients undergoing benign cranial nerve tumor resection.
Design/Setting/Participants This retrospective cohort analysis included patients enrolled in the ACS-NSQIP registry
from 2007 through 2013 with a diagnosis of a benign cranial nerve neoplasm.
Main Outcome Measures Primary outcomes included postoperative morbidity and mortality. Readmission and
reoperation served as secondary outcomes.
Results A total of 565 patients were identified. Mean (median) operative time was 398 (370)
minutes. The 30-day complication, readmission, and return to the operating room rates
were 9.9%, 9.9%, and 7.3%, respectively, on unadjusted analyses. CSF leak requiring
reoperation or readmission occurred at a rate of 3.1%. On multivariable regression
analysis, operations greater than 413 minutes were associated with an increased odds
of overall complication (OR 4.26, 95% CI 2.08–8.72), return to the operating room
(OR 2.65, 95% CI 1.23–5.67), and increased length of stay(1.6 days, 95% CI 0.94–2.23
days). Each additional minute of operative time was associated with an increased odds
of overall complication (OR 1.004, 95% CI 1.002–1.006) and increased length of stay
(0.006 days, 95% CI 0.004–0.008).
Conclusion Increased operative time in patients undergoing surgical resection of a benign cranial
nerve neoplasm was associated with an increased rate of complications.
Keywords
acoustic neuroma - vestibular schwannoma - skull base - operative time - complications
- national surgical quality improvement program