Nierenbiopsien – Histologische Veränderungen bei älteren Patienten

Zusammenfassung

Nierenerkrankungen älterer Patienten stellen aufgrund der epidemiologischen Entwicklung ein zunehmendes klinisches Problem dar. Wie bei jüngeren Patienten stellt auch bei älteren, komorbiden Patienten die Nierenbiopsie den Goldstandard der Diagnostik einer Nierenerkrankung, und hier v.a. der Glomerulonephritiden, dar. Dies umso mehr, als sich die Durchführung und Komplikationsrate der Nierenbiopsie bei älteren Patienten nicht von derjenigen jüngerer Patienten unterscheidet und auch die Befunde und deren therapeutische und prognostische Konsequenzen durchaus vergleichbar sind. Insofern ist es wichtig und sinnvoll, bei entsprechender Indikation gerade auch bei älteren Patienten zeitnah eine Nierenbiopsie anzustreben.

Summary

Renal disease in elderly patients is an increasing clinical problem. As in younger patients with renal disease, kidney biopsy is the gold standard to diagnose renal disease, particulary glomerular disease, even more important since neither the performance nor the complication rate of a kidney biopsy in elderly patients is different from that in younger patients. Moreover, histological findings and in particular their therapeutical and prognostical consequences are also comparable. Thus, if there is a clear indication it makes enormous sense and is particularly important in elderly patients to aim for an immediate kidney biopsy.

Key words

elderly - kidney - renal disease - renal biopsy - glomerulosclerosis - glomerular number

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