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Synthesis 2016; 48(16): 2572-2580
DOI: 10.1055/s-0035-1561466
DOI: 10.1055/s-0035-1561466
feature
Preparation of Morpholines and Benzoxazines Starting from Nitroepoxides
Further Information
Publication History
Received: 25 April 2016
Accepted after revision: 28 April 2016
Publication Date:
16 June 2016 (online)
Abstract
Nitroepoxides are easily transformed into 2,3-disubstituted morpholines and 2,3-disubstituted benzoxazines in a two-step sequence by treatment with N-methylethanolamine and N-methyl-2-hydroxyaniline, respectively, in a highly stereoselective fashion.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1561466.
- Supporting Information
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