Aktuelle Trends bei der Strahlenbehandlung nach chirurgischer Entfernung von Weichgewebesarkomen der Extremitäten und des Rumpfes

Zusammenfassung

Neben der zentralen Rolle der Chirurgie hat die Strahlentherapie einen wichtigen Platz in der modernen multimodalen Therapiestrategie von Weichteiltumoren. Sie kann postoperativ als adjuvante Radiotherapie oder präoperativ neoadjuvant bei primär nicht weit im Gesunden resezierbaren Tumoren, selten als definitive primäre Therapie bei Inoperabilität durchgeführt werden. Die adjuvante Radiotherapie führt zu einer Verbesserung sowohl der lokalen Kontrollraten als auch des Überlebens. Aufgrund der vielen unterschiedlichen Entstehungsorte und vielen histologischen Subtypen sollten Patienten mit Weichteilsarkomen an Zentren mit entsprechender wissenschaftlicher und klinischer Expertise behandelt werden. Hinsichtlich der Radioonkologie sollten moderne Konzepte und verfeinerte Techniken individualisiert zum Einsatz kommen.

Abstract

Besides surgery, radiotherapy plays its well-established part in the multimodality treatment of soft-tissue sarcomas. It can be delivered before or after surgery with similar control rates. Adjuvant radiotherapy increases the local control rates as well as the overall survival in intermediate or high-grade soft-tissue sarcomas. Due to the complex and sophisticated nature of the treatment, patients should be referred to specialised centres where modern radiotherapeutic options like intensity modulated radiotherapy and image-guided radiotherapy can be offered.

Schlüsselwörter

Strahlentherapie - Weichgewebssarkome - adjuvante Therapie - moderne Techniken

Key words

radiotherapy - soft-tissue sarcomas - adjuvant therapy - modern techniques

• Literatur

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