Abstract
Present study evaluate wound healing activity of ethanolic extract of stem bark of
Pongamia pinnata (PP). Evaluation of wound healing activity, 2 wound models were used i. e., incision and
excision wounds were perform in this study on Albino wistar rats (150–200 g). The
rats were been treated with 10% and 5% ointment base formulation at dose 15 µl/wound
topically. The parameters studied were breaking strength in case of incision wounds,
epithelization period and wound area in case of excision wound. The ethanolic extract
treated group showed a significant (P<0.01) reduction in the wound breaking strength
in incision type of wound model and significant increase in epithelization period
and reduction in percentage of wound area in excision type of wound model as compared
to control group. Extract treated groups showed significant (P<0.01) improvement in
all the wound healing parameters of incision and excision wound models as compared
to control. This study justify the traditional use of ethanolic extract of Pongamia pinnata stem bark shows wound healing property.
Key words
pongamia pinnata
- Epithelization period - Wound breaking strength - Incision wound - Excision wound
