Semin Plast Surg 2014; 28(02): 064-068
DOI: 10.1055/s-0034-1376261
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

A Review of Vascular Anomalies: Genetics and Common Syndromes

Elizabeth Killion
1   Division of Plastic Surgery, Baylor College of Medicine, Houston, Texas
,
Kriti Mohan
1   Division of Plastic Surgery, Baylor College of Medicine, Houston, Texas
,
Edward I. Lee
1   Division of Plastic Surgery, Baylor College of Medicine, Houston, Texas
› Author Affiliations
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Publication History

Publication Date:
31 May 2014 (online)

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Abstract

Vascular tumors and malformations are unique in that affected cells exhibit disrupted angiogenesis. The current treatment options often yield suboptimal results. New insight into the genetics and molecular basis of vascular anomalies may pave the way for potential development of targeted therapy. The authors review the genetic and molecular basis of vascular anomalies and common associated syndromes.