Regenerative Knorpeltherapie

Knorpelregenerative Therapieverfahren sind in den letzten Jahren feste Bestandteile der orthopädisch-traumatologischen Behandlung geworden. Für die Therapie ist es erforderlich, die Schädigung sowohl als mechanisches, aber auch als biochemisches Problem zu erkennen.

• Literatur

• 1 Bentley G, Biant LC, Vijayan S et al. Minimum ten-year results of a prospective randomised study of autologous chondrocyte implantation versus mosaicplasty for symptomatic articular cartilage lesions of the knee. J Bone Joint Surg Br 2012; 94: 504-509
• 2 Brittberg M, Winalski CS. Evaluation of cartilage injuries and repair. J Bone Joint Surg Am 2003; 85-A (Suppl. 02) 58-69
• 3 Gille J, Behrens P, Volpi P et al. Outcome of autologous matrix induced chondrogenesis (AMIC) in cartilage knee surgery: data of the AMIC Registry. Arch Orthop Trauma Surg 2013; 133: 87-93
• 4 Hempfling H, Bohndorf K. Begutachtung des Knorpelschadens. Trauma Berufskrankh 2007; 9: 284-295
• 5 Kreuz PC, Steinwachs MR, Erggelet C et al. Results after microfracture of full-thickness chondral defects in different compartments in the knee. Osteoarthritis Cartilage 2006; 14: 1119-1125
• 6 Minas T, Gomoll AH, Solhpour S et al. Autologous chondrocyte implantation for joint preservation in patients with early osteoarthritis. Clin Orthop Relat Res 2010; 468: 147-157
• 7 Mithoefer K, Williams 3rd RJ, Warren RF et al. The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort study. J Bone Joint Surg Am 2005; 87: 1911-1920
• 8 Niemeyer P, Porichis S, Steinwachs M et al. Long-term outcomes after first-generation autologous chondrocyte implantation for cartilage defects of the knee. Am J Sports Med 2014; 42: 150-157
• 9 Peterson L, Vasiliadis HS, Brittberg M et al. Autologous chondrocyte implantation: a long-term follow-up. Am J Sports Med 2010; 38: 1117-1124
• 10 Welsch GH, Mamisch TC, Zak L et al. Morphological and biochemical T2 evaluation of cartilage repair tissue based on a hybrid double echo at steady state (DESS-T2 d) approach. J Magn Reson Imaging 2011; 34: 895-903
• 11 Widuchowski W, Widuchowski J, Trzaska T. Articular cartilage defects: study of 25, 124 knee arthroscopies. Knee 2007; 14: 177-182