Herpes Simplex Virus Reactivation and Disease during Treatment for Childhood Acute Lymphoblastic Leukemia

Key words

childhood - acute lymphoblastic ­leukemia - disseminated herpes simplex infection - induction - re-induction - herpes encephalitis

Schlüsselwörter

Kind - akute lymphoblastische Leukämie - disseminierte Herpes-simplex-Infektion - Induktion - Reinduktion - Herpes encephalitis

• References

• 1 Blot N, Schneider P, Young P et al. Treatment of an acyclovir and foscarnet-resistant herpes simplex virus infection with cidofovir in a child after an unrelated bone marrow transplant. Bone Marrow Transplant 2000; 26: 903-905
• 2 Carrega G, Castagnola E, Canessa A et al. Herpes simplex virus and oral mucositis in children with cancer. Support Care Cancer 1994; 2: 266-269
• 3 de Mendonca RM, de Araujo M, Levy CE et al. Prospective evaluation of HSV, Candida spp., and oral bacteria on the severity of oral mucositis in pediatric acute lymphoblastic leukemia. Support Care Cancer 2012; 20: 1101-1107
• 4 Holzinger D, Kuhn J, Ehlert K et al. HSV-1 viremia as a potential cause of febrile neutropenia in an immunocompromised child. J Pediatr Hematol Oncol 2010; 32: e19-e21
• 5 Ikegaya S, Yoshida A, Iwasaki H et al. Esophageal erosion as a possible bacterial entry site in an acute lymphoblastic leukemia patient with sepsis. Int J Hematol 2003; 77: 395-398
• 6 Lehrnbecher T, Beutel K, Belohradsky B et al. Infektionen bei pädiatrisch-onkologischen Patienten. In: Scholz H, Behloradsky B, Bialek R. et al. (eds.). DGPI Handbuch: Infektionen bei Kindern und Jugendlichen Stuttgart. New York: Thieme; 2009: 641-651
• 7 Lonnqvist B, Palmblad J, Ljungman P et al. Oral acyclovir as prophylaxis for bacterial infections during induction therapy for acute leukaemia in adults. The Leukemia Group of Middle Sweden. Support Care Cancer 1993; 1: 139-144
• 8 Markoulatos P, Georgopoulou A, Kotsovassilis C et al. Detection and typing of HSV-1, HSV-2, and VZV by a multiplex polymerase chain reaction. J Clin Lab Anal 2000; 14: 214-219
• 9 Moricke A, Lauten M, Beier R et al. Prediction of Outcome by Early Response in Childhood Acute Lymphoblastic Leukemia. Klin Padiatr 2013; 225 (S 01) S50-S56
• 10 Pichler H, Reismuller B, Steiner M et al. The inferior prognosis of adolescents with acute lymphoblastic leukaemia (ALL) is caused by a higher rate of treatment-related mortality and not an increased relapse rate – a population-based analysis of 25 years of the Austrian ALL-BFM (Berlin-Frankfurt-Munster) Study Group. Br J Haematol 2013; 161: 556-565
• 11 Prucker C, Attarbaschi A, Peters C et al. Induction death and treatment-related mortality in first remission of children with acute lympho­blastic leukemia: a population-based analysis of the Austrian Berlin-Frankfurt-Munster study group. Leukemia 2009; 23: 1264-1269
• 12 Ramphal R, Grant RM, Dzolganovski B et al. Herpes simplex virus in febrile neutropenic children undergoing chemotherapy for cancer: a prospective cohort study. Pediatr Infect Dis J 2007; 26: 700-704
• 13 Sauerbrei A, Schmitt S, Scheper T et al. Seroprevalence of herpes simplex virus type 1 and type 2 in Thuringia, Germany, 1999 to 2006. Euro Surveill 2011; 16 doi: pii: 20005
• 14 Schrappe M, Moricke A, Reiter A et al. Key Treatment Questions in Childhood Acute Lymphoblastic Leukemia: Results in 5 Consecutive Trials Performed by the ALL-BFM Study Group From 1981 to 2000. Klin Padiatr 2013; 225 (S 01) S62-S72
• 15 Stanberry LR, Floyd-Reising SA, Connelly BL et al. Herpes simplex viremia: report of eight pediatric cases and review of the literature. Clin Infect Dis 1994; 18: 401-407
• 16 Styczynski J, Reusser P, Einsele H et al. Management of HSV, VZV and EBV infections in patients with hematological malignancies and after SCT: guidelines from the Second European Conference on Infections in Leukemia. Bone Marrow Transplant 2009; 43: 757-770