Esophageal disease

During the 2013 Digestive Disease Week (DDW) (May 18 – 21, Orlando, Fla) many exciting and important endoscopy-related studies on esophageal disease were presented. Most studies were on diagnosis and endoscopic treatment of Barrett’s esophagus and related neoplasia. However, also other topics such as eosinophilic esophagitis, peroral endoscopic myotomy (POEM) in achalasia patients, Zenker’s myotomy, and endoscopic treatment of squamous cell cancer had several relevant scientific contributions.

The following review discusses my personal subjective selection of 18 important endoscopy abstracts from this year’s DDW.

• References

• 1 Schoepfer A, Portmann S, Safroneeva E et al. Influence of long-term treatment with topical corticosteroids on natural course of eosinophilic esophagitis and correlation between symptoms and endoscopy, histology and blood eosinophils. Gastroenterology 2013; 144: 154
• 2 Schoepfer A, Safroneeva E, Bussmann C et al. Duration of untreated inflammation represents the main risk factor for stricture development in eosinophilic esophagitis. Gastroenterology 2013; 144: 485
• 3 Dellon ES, Kim HP, McConville S et al. Eosinophilic esophagitis is a progressive fibrostenotic disease: insights from a phenotypic analysis. Gastroenterology 2013; 144: 485
• 4 Iacopini F, Bizzotto A, Bella A et al. Flexible endoscopic myotomy of Zenker’s diverticulum: feasibility, long-term clinical efficiacy, and prognostic variables of success of the diverticuloscope-assisted technique (abstract). Gastrointest Endosc 2013; 77: AB350
• 5 Inoue H, Ikeda H, Onimaru M et al. Clinical results in 300 cases of POEM for esophageal achalasia: a single institute registered prospective study (abstract). Gastrointest Endosc 2013; 77: AB121
• 6 Von Renteln D, Fuchs KH, Fockens P et al. Endoscopic versus surgical myotomy for idiopathic achalasia: results of a prospective multicenter study and comparison with laparoscopic surgery (abstract). Gastrointest Endosc 2013; 77: AB122
• 7 Wang XY, Xu MD, Yao LQ et al. Submucosal tunnel endoscopic resection for submucosal tumors of the esophagogastric junction originating from the muscularis propria layer: a feasibility study (abstract). Gastrointest Endosc 2013; 77: AB190
• 8 Zavos C, Verbeek RE, Leenders M et al. Prevalence and natural history of low-grade dysplasia in patients with Barrett’s esophagus (abstract). Gastrointest Endosc 2013; 77: AB327
• 9 Duits LC, Phoa KYN, Curvers WL et al. Low-grade dysplasia in Barrett’s esophagus has a high risk of progression when confirmed by a panel of expert pathologists. Gastroenterology 2013; 144 (Suppl. 01) 73
• 10 Phoa KYN, van Vilsteren F, Pouw R et al. Radiofrequency ablation in Barrett’s esophagus with confirmed low-grade dysplasia: interim results of a European multicenter randomized controlled trial (SURF). Gastroenterology 2013; 144 (Suppl. 01) 187
• 11 Phoa N, Pouw R, Bisschops R et al. Radiofrequency ablation combined with endoscopic resection is highly effective for eradication of early Barrett’s neoplasia: Final results of a large prospective European multicenter study (EURO-II) (abstract). Gastrointest Endosc 2013; 77: AB137
• 12 Fudman DI, Lightdale CJ, Poneros JM et al. Correlation between endoscopist radiofrequency ablation volume and response rate in the treatment of Barrett’s esophagus (abstract). Gastrointest Endosc 2013; 77: AB215
• 13 Bulsiewicz WJ, Dellon ES, Lyday WD et al. Predictors of recurrent Barrett’s esophagus after successful radiofrequency ablation in a nationwide, multicenter cohort: results from the U.S. RFA registry. Gastroenterology 2013; 143: 1
• 14 Haidry RJ, Butt MA, Gupta A et al. Patients undergoing radiofrequency ablation (RFA) for Barrett’s related neoplasia have improved outcomes with decreasing length’s of baseline Barrett’s esophagus (BE) and increasing number of RFA sessions (abstract). Gastrointest Endosc 2013; 77: AB138
• 15 Holt BA, Jayaserkeran V, Fahrtash-Bahin F et al. Single session Barrett’s excision and temporary stent (Beats) for high-grade dysplasia and early cancer in short-segment disease: a prospective feasibility study (abstract). Gastrointest Endosc 2013; 77: AB334
• 16 Zhang Y, Boerwinkel DF, He S et al. A randomised trial comparing multiband mucosectomy and ER-CAP for endoscopic piecemeal resection of early squamous neoplasia of the esophagus (abstract). Gastrointest Endosc 2013; 77: AB187
• 17 Haidry RJ, Banks MR, Butt MA et al. Radiofrequency ablation (RFA) confers sustained benefit for squamous high grade dysplasia (HGD) and early squamous cell carcinoma (SCC) in patients who do not progress following the first treatment (abstract). Gastrointest Endosc 2013; 77: AB348
• 18 Katada C, Muto M, Yokohama T et al. Japan esophageal cohort (Jec) study fort he risk of the field cancerization phenomenon in esophageal squamous cell carcinoma after endoscopic resection (abstract). Gastrointest Endosc 2013; 77: AB342