Prenatal Suspicion of Kaposiform Hemangioendo­thelioma in Siblings: Different Clinical Manifestation and Emergency Relief

Key words

kaposiform ­hemangioendothelioma - hematogenous pleural ­effusion - Kasabach-Merritt ­phenomenon - fetal anemia - tufted angioma

Schlüsselwörter

Kaposiformes ­Hämangioendotheliom - hämatogener Pleuraerguss - Kasabach-Merritt Phänomen - fetale Anämie - tufted Angiom

• References

• 1 Chen RL, Chang PY, Hsu YH et al. Recurrent life-threatening hemo­thorax in an infant with pleurocutaneous kaposiform hemangio-endothelioma. J Pediatr Hematol Oncol 2006; 28: 630-632
• 2 Chiu YE, Drolet BA, Blei F et al. Variable response to propranolol treatment of Kaposiform Hemangioendothelioma, Tufted Angioma, and Kasabach-Merritt Phenomenon. Pediatr Blood Cancer Feb 2 2012,
• 3 Croteau SE, Liang MG, Kozakewich HP et al. Kaposiform Hemangioendothelioma: atypical features and risks of Kasabach-Merritt Phenomenon in 107 referrals. J Pediatr 2012; PMID: 22871490
• 4 Fernandez-Pineda I, Lopez-Gutierrez JC, Ramirez G et al. Vincristine-ticlopidine-aspirin: an effective therapy in children with Kasabach-Merritt phenomenon associated with vascular tumors. Pediatr Hematol Oncol 2010; 27: 641-645
• 5 Gurevich M, Fritsche K, Rupprath G. Frühgeborenes der 26+3 SSW mit ausgeprägter neonataler Hämangiomatose, ein Fallbericht. Klin Padiatr 2010; 222: S69-S70
• 6 Hermans DJ, van Beynum IM, van der Vijver RJ et al. Kaposiform hemangioendothelioma with Kasabach-Merritt syndrome: a new indication for propranolol treatment. J Pediatr Hematol Oncol 2011; 33: e171-e173
• 7 Mulliken JB, Enjolras O. Congenital hemangiomas and infantile hemangioma: missing links. J Am Acad Dermatol 2004; 50: 875-882
• 8 Politi C, Brumberg J, Knöppel C et al. Hämangiom-Therapie mit Propranolol. Klin Padiatr 2010; 222: 112
• 9 Radhi M, Carpenter SL. Thrombotic Microangiopathies. ISRN Hematol 2012; 2012 310596
• 10 San Miguel FL, Spurbock W, Budding C et al. Kaposiform hemangioendothelioma a rare cause of spontaneous hemothorax in infancy. Review of the Literature. J Pediatr Surg 2008; 43: e37-e41