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Int J Sports Med 2013; 34(03): 214-217
DOI: 10.1055/s-0032-1316360
Training & Testing
© Georg Thieme Verlag KG Stuttgart · New York

Determination of the Maximal Lactate Steady State in Obese Zucker Rats

J. A. Almeida
1   Physical Education, Catholic University of Brasilia, Taguatinga, Brazil
2   Center of Proteomic and Biochemical Analyses, Post-Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil
,
B. A. Petriz
1   Physical Education, Catholic University of Brasilia, Taguatinga, Brazil
2   Center of Proteomic and Biochemical Analyses, Post-Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil
,
C.P. C. Gomes
1   Physical Education, Catholic University of Brasilia, Taguatinga, Brazil
2   Center of Proteomic and Biochemical Analyses, Post-Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil
,
L.A. O. Rocha
1   Physical Education, Catholic University of Brasilia, Taguatinga, Brazil
2   Center of Proteomic and Biochemical Analyses, Post-Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil
,
R. W. Pereira
1   Physical Education, Catholic University of Brasilia, Taguatinga, Brazil
2   Center of Proteomic and Biochemical Analyses, Post-Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil
,
O. L. Franco
1   Physical Education, Catholic University of Brasilia, Taguatinga, Brazil
2   Center of Proteomic and Biochemical Analyses, Post-Graduate Program in Genomic Sciences and Biotechnology, Catholic University of Brasilia, Brasilia, Brazil
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Publication History



accepted after revision 28 May 2012

Publication Date:
12 September 2012 (online)

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Abstract

This study aims to identify the maximum lactate steady state (MLSS) in obese rats in order to provide a more effective tool in the exercise training prescription for this important animal model. To make such determination, obese (Zucker, n=5) (390.0±18.8 g) and lean (Wistar, n=5) (227.3±26.2 g) rats were studied. After adaptation of animals to treadmill, the MLSS was determined by using 3 different velocities (10 m.min − 1, 12.5 m.min − 1 and 15 m.min − 1 for Zucker and 15 m.min − 1, 20 m.min − 1 and 25 m.min − 1 for Wistar). The MLSS was defined as the highest blood lactate concentration that increased up to 1 mmol.L − 1 during constant exercise. In obese rats, the MLSS was found in a velocity considerably lower than in lean controls (12.5 m.min − 1 and 20 m.min − 1), respectively (p<0.05). Therefore, the identification of MLSS in obese Zucker rats is an important tool for exercise prescription and evaluation in obese rat models.

Key words

MLSS - obese Zucker rat - treadmill running
 

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