HDL-C: Das gute Cholesterin schlecht für die Nerven?

Zusammenfassung

Die Interpretation der Serumlipide in der Labordiagnostik wird stark beeinflusst durch ihre Bedeutung auf kardiovaskulärer Ebene. Allerdings steht die Senkung der Cholesterinwerte mit Statinen zunehmend in der Kritik, da die negativen Folgen eines erniedrigten Cholesterinspiegels für das Nervensystem inzwischen gut dokumentiert sind.

30 Jahre Praxiserfahrung mit dem proteomischen Profil nach C. E. I. A. haben den Verdacht aufkommen lassen, dass ein (sehr) hohes HDL-Cholesterin Belastungszeuge oder sogar Verursacher für Erkrankungen des Nervensystems sein könnte. Eine Neuorientierung der Zielwerte für Lipid- und Lipoproteinparameter nach Alter und Geschlecht gelingt durch die Analyse von sehr großen Patientenkollektiven.

Abstract

Serum lipids are usually interpreted in regard to their cardiovascular significance. But lowering cholesterol with statins is more and more criticized as the adverse results for the nervous system have been well documented by now. 30 years of experience with functional proteomics according to C. E. I. A. have raised the suspicion, that a (very) high HDL cholesterol is a sign if not even the very reason for illnesses of the central nervous system. A realignment of the target values for lipids and lipoproteins related to age and sex can be achieved through analysis of large patient populations.

Schlüsselwörter

HDL-Cholesterin - C. E. I. A. Profil - Neuropsychiatrie

Keywords

HDL cholesterol - functional proteomics according to C. E. I. A. - neuropsychiatry

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