Endoscopy 2013; 45(S 02): E44-E45
DOI: 10.1055/s-0032-1309927
Cases and Techniques Library (CTL)
© Georg Thieme Verlag KG Stuttgart · New York

Percutaneous direct-endoscopic necrosectomy for walled-off pancreatic necrosis

N. Yamamoto
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
H. Isayama
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
N. Takahara
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
N. Sasahira
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
K. Miyabayashi
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
S. Mizuno
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
K. Kawakubo
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
D. Mohri
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
H. Kogure
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
T. Sasaki
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
M. Tada
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
,
K. Koike
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
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Corresponding author

N. Yamamoto, MD
Department of Gastroenterology
Graduate School of Medicine
The University of Tokyo
7-3-1 Hongo, Bunkyo-ku
Tokyo 113-8655
Japan   
Fax: +81-3-38140021   

Publikationsverlauf

Publikationsdatum:
22. März 2013 (online)

 

We report a case where percutaneous direct-endoscopic necrosectomy was successfully used to treat walled-off pancreatic necrosis (WOPN) that could not be accessed via the transluminal approach.

A 36-year-old woman with severe alcoholic pancreatitis was referred to our institute. The computed tomography (CT) scan showed extensive WOPN (larger diameter 26 cm) spreading from the level of the pancreas to the pelvic floor ([Fig. 1]). Citrobacter freundii was detected from the aspiration fluid obtained from the WOPN. Transluminal observation of the WOPN by endoscopic ultrasonography was not possible, because of the presence of an inflammatory duodenal stricture.

Zoom Image
Fig. 1 A contrast-enhanced computed tomography (CT) scan showed extensive walled-off pancreatic necrosis (WOPN): a upper abdomen, b pelvic region.

The patient initially underwent percutaneous drainage 17 days after the onset of pancreatitis. A stent was placed in the right urinary tract to prevent urinary duct injury during necrosectomy. In total, two percutaneous drainage catheters were placed in the right flank region and right lower abdomen. During the second session, the percutaneous fistula in the right flank was dilated up to 18 mm with a balloon dilator (CRETM wire-guided balloon dilator; Boston Scientific, Natik, Massachusetts, USA). Next, a flexible overtube (diameter 20 mm), whose length had been shortened by 20 cm, was placed to maintain carbon dioxide insufflation of the cavity ([Fig. 2]).

Zoom Image
Fig. 2 Direct necrosectomy: a the flexible overtube was placed from the right flank region, b the gastroscope reached the pelvic floor.
Zoom Image

Direct necrosectomy was performed using a gastroscope through the overtube. All the procedures were performed under intravenous anesthesia. The maximum duration of necrosectomy was 2 hours. Abundant solid and purulent necrotic material was removed using a snare, a basket catheter, and alligator forceps. At the end of each necrosectomy session, three drainage catheters (diameter 24 Fr) were placed to maintain the fistula, and two irrigation catheters were also placed ([Fig. 3]). After 11 necrosectomy sessions, the patient was discharged without complications.

Zoom Image
Fig. 3 Three drainage catheters and two irrigation catheters inserted from the single fistula.

Endoscopic necrosectomy via the percutaneous approach can be used as a treatment option if the WOPN is located adjacent to the abdominal wall.

Endoscopy_UCTN_Code_TTT_1AS_2AD


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Competing interests: None

  • References

  • 1 Seifert H, Biermer M, Schmitt W et al. Transluminal endoscopic necrosectomy after acute pancreatitis: a multicentre study with long-term follow-up (the GEPARD Study). Gut 2009; 58: 1260-1266
  • 2 van Santvoort HC, Besselink MG, Bakker OJ et al. A step-up approach or open necrosectomy for necrotizing pancreatitis. N Engl J Med 2010; 362: 1491-1502
  • 3 van Baal MC, van Santvoort HC, Bollen TL et al. Systematic review of percutaneous catheter drainage as primary treatment for necrotizing pancreatitis. Br J Surg 2011; 98: 18-27

Corresponding author

N. Yamamoto, MD
Department of Gastroenterology
Graduate School of Medicine
The University of Tokyo
7-3-1 Hongo, Bunkyo-ku
Tokyo 113-8655
Japan   
Fax: +81-3-38140021   

  • References

  • 1 Seifert H, Biermer M, Schmitt W et al. Transluminal endoscopic necrosectomy after acute pancreatitis: a multicentre study with long-term follow-up (the GEPARD Study). Gut 2009; 58: 1260-1266
  • 2 van Santvoort HC, Besselink MG, Bakker OJ et al. A step-up approach or open necrosectomy for necrotizing pancreatitis. N Engl J Med 2010; 362: 1491-1502
  • 3 van Baal MC, van Santvoort HC, Bollen TL et al. Systematic review of percutaneous catheter drainage as primary treatment for necrotizing pancreatitis. Br J Surg 2011; 98: 18-27

Zoom Image
Fig. 1 A contrast-enhanced computed tomography (CT) scan showed extensive walled-off pancreatic necrosis (WOPN): a upper abdomen, b pelvic region.
Zoom Image
Fig. 2 Direct necrosectomy: a the flexible overtube was placed from the right flank region, b the gastroscope reached the pelvic floor.
Zoom Image
Zoom Image
Fig. 3 Three drainage catheters and two irrigation catheters inserted from the single fistula.