Abstract
Twelve new dammarane-type glycosides (1–12) were isolated from the ethanol extract from the roots of a wild-type of Gynostemma pentaphyllum. The structures of the compounds were elucidated by 1D and 2D NMR spectroscopic analysis as well as by chemical degradation. The compounds contained six structurally diverse aglycons similar to those of the reported ginseng saponins with differences in the oligosaccharide moieties.
Key words
Gynostemma pentaphyllum
- Cucurbitaceae - gypenoside - dammarane-type glycoside - saponins
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Prof. Li-Hong Hu
Shanghai Institute of Materia Medica
Chinese Academy of Sciences
Shanghai 201203
PR China
Phone: +86 21 20 23 19 65
Fax: +86 21 20 23 19 65
Email: simmhulh@mail.shcnc.ac.cn
Prof. Yaping Xiao
Key Laboratory of Medicinal Plant Resources and Natural Pharmaceutical Chemistry
Ministry of Education
Shaanxi Normal University
Xi'an 710062
PR China
Phone: +86 29 85 31 02 66
Fax: +86 29 85 31 03 75
Email: yapingxiao@snnu.edu.cn
