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Semin Thromb Hemost 2011; 37(7): 763-761
DOI: 10.1055/s-0031-1297167
© Thieme Medical Publishers

Thrombosis in Children

Christine A. Macartney1 , Anthony K.C. Chan2
  • 1Department of Paediatric Haematology, Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland, United Kingdom
  • 2Thrombosis & Atherosclerosis Research Institute (TaARI) and Department of Paediatrics, McMaster University, Hamilton, Ontario, Canada
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Publication History

Publication Date:
20 December 2011 (online)

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ABSTRACT

Thrombosis in children is becoming more prevalent due to increased awareness of these issues in the pediatric population and advances in medicine. Management of affected children are challenging due to differences in their hemostatic system compared with adults. Prospective, controlled trials for management/treatment of children with thrombosis are lacking. Many of the available guidelines for treatment of thrombosis in children are extrapolated from adult data and do not account for the uniqueness of the pediatric hemostatic system, although more research and data are becoming available. This review will focus on children over 1 year of age, including adolescents, looking at the etiology of thrombosis, diagnosis, management options, and any associated complications in this pediatric population.

KEYWORDS

Thrombosis - pediatrics - anticoagulation

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Christine A. MacartneyM.B. D.C.H. M.R.C.P. F.R.C.Path. 

Department of Paediatric Haematology, Royal Belfast Hospital for Sick Children, Falls Road

Belfast BT12 6BE, Northern Ireland, United Kingdom

Email: christine.macartney@belfasttrust.hscni.net