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Augenheilkunde up2date 2012; 2(1): 35-46
DOI: 10.1055/s-0031-1280458
Katarakt und refraktive Chirurgie

© Georg Thieme Verlag KG Stuttgart · New York

Kataraktchirurgie und altersbedingte Makuladegeneration

H. Baatz1 , 2
  • 1Aurelios Augenzentrum Recklinghausen
  • 2Klinik für Augenheilkunde, Johann Wolfgang Goethe-Universität Frankfurt am Main
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Publication History

Publication Date:
18 January 2012 (online)

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Die Katarakt stellt die häufigste Ursache einer reversiblen Sehverschlechterung beim alternden Menschen dar. In Deutschland ist die altersbedingte Makuladegeneration (AMD) die häufigste Ursache einer gesetzlich anerkannten hochgradigen Sehbehinderung oder Erblindung. Es werden Fragen erörtert, die sich bei der Behandlung von Patienten mit gleichzeitigem Vorliegen von Katarakt und AMD stellen. Bei adäquater Indikationsstellung profitieren auch Patienten mit altersbedingter Makuladegeneration von einer Kataraktoperation. Der Visusanstieg durch die Operation ist bei der Mehrzahl der Patienten über Jahre nachweisbar. Nach derzeitigem Erkenntnisstand stellt die Kataraktoperation kein Risiko für die Progredienz einer AMD dar. Die Verschlechterung einer AMD nach Kataraktoperation ist ein zufälliges Ereignis, das durch die hohe Komorbidität von Katarakt und AMD bedingt ist. Es gibt kein belastbares Datenmaterial, das den Nutzen der Implantation von Blaufilter-Intraokularlinsen belegt.

Quellenangaben

  • 1 Anonymous. Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study Group.  Arch Ophthalmol. 1992;  110 1701-1708
    Google Scholar
  • 2 Armbrecht A M, Findlay C, Aspinall P A et al. Cataract surgery in patients with age-related macular degeneration: one-year outcomes.  J Cataract Refract Surg. 2003;  29 686-693
    Google Scholar
  • 3 Armbrecht A M, Findlay C, Kaushal S et al. Is cataract surgery justified in patients with age related macular degeneration? A visual function and quality of life assessment.  Br J Ophthalmol. 2000;  84 1343-1348
    Google Scholar
  • 4 Augustin A J. Blaufilter-Intraokularlinsen – derzeitige Datenlage.  Klin Monatsbl Augenheilkd. 2010;  227 617-623
    Google Scholar
  • 5 Baatz H, Darawsha R, Ackermann H et al. Phacoemulsification does not induce neovascular age-related macular degeneration.  Invest Ophthalmol Vis Sci. 2008a;  49 1079-1083
    Google Scholar
  • 6 Baatz H, Darawsha R, Scharioth G et al. Visusverlauf nach Kataraktoperation bei Patienten mit altersassoziierter Makulopathie.  Ophthalmologe. 2008b;  105 927-930
    Google Scholar
  • 7 Blair C J, Ferguson J J. Exacerbation of senile macular degeneration following cataract extraction.  Am J Ophthalmol. 1979;  87 77-83
    Google Scholar
  • 8 Bradford-Hill A. The environment and disease: association or causation?.  Proc R Soc Med. 1965;  58 295-300
    Google Scholar
  • 9 Chew E Y, Sperduto R D, Milton R C et al. Risk of advanced age-related macular degeneration after cataract surgery in the Age-Related Eye Disease Study: AREDS report 25.  Ophthalmology. 2009;  116 297-303
    Google Scholar
  • 10 Cugati S, Mitchell P, Rochtchina E et al. Cataract surgery and the 10-year incidence of age-related maculopathy: the Blue Mountains Eye Study.  Ophthalmology. 2006;  113 2020-2025
    Google Scholar
  • 11 de Jong P T V M, Lubsen J. The standard gamble between cataract extraction and AMD.  Graefes Arch Clin Exp Ophthalmol. 2004;  242 103-105
    Google Scholar
  • 12 Dong L M, Stark W J, Jefferys J L et al. Progression of age-related macular degeneration after cataract surgery.  Arch Ophthalmol. 2009;  127 1412-1419
    Google Scholar
  • 13 Eberhard R, Roberti P, Prünte C. Intraindividual comparison of color perception and contrast sensitivity with and without a blue light-filtering intraocular lens.  Eur J Ophthalmol. 2009;  19 235-239
    Google Scholar
  • 14 Finger R P, Fimmers R, Holz F G et al. Incidence of blindness and severe visual impairment in Germany: projections for 2030.  Invest Ophthalmol Vis Sci. 2011;  52 4381-4389
    Google Scholar
  • 15 Forooghian F, Agrón E, Clemons T E et al. Visual acuity outcomes after cataract surgery in patients with age-related macular degeneration: age-related eye disease study report no. 27.  Ophthalmology. 2009;  116 2093-2100
    Google Scholar
  • 16 Graney M J, Applegate W B, Miller S T et al. A clinical index for predicting visual acuity after cataract surgery.  Am J Ophthalmol. 1988;  105 460-465
    Google Scholar
  • 17 Green D G. Testing the vision of cataract patients by means of laser-generated interference fringes.  Science. 1970;  168 1240-1242
    Google Scholar
  • 18 Henderson B A, Grimes K J. Blue-blocking IOLs: a complete review of the literature.  Surv Ophthalmol. 2010;  55 284-289
    Google Scholar
  • 19 Ho L, Boekhoorn S S, Liana et al. Cataract surgery and the risk of aging macula disorder: the rotterdam study.  Invest Ophthalmol Vis Sci. 2008;  49 4795-4800
    Google Scholar
  • 20 Hooper C Y, Lamoureux E L, Lim L et al. Cataract surgery in high-risk age-related macular degeneration: a randomized controlled trial.  Clin Experiment Ophthalmol. 2009;  37 570-576
    Google Scholar
  • 21 Kahn H A, Leibowitz H M, Ganley J P et al. The Framingham Eye Study. II. Association of ophthalmic pathology with single variables previously measured in the Framingham Heart Study.  Am J Epidemiol. 1977;  106 33-41
    Google Scholar
  • 22 Kaiserman I, Kaiserman N, Elhayany A et al. Cataract surgery is associated with a higher rate of photodynamic therapy for age-related macular degeneration.  Ophthalmology. 2007;  114 278-282
    Google Scholar
  • 23 Khalifa Y M, Pantanelli S M. Quiescent posterior capsule trauma after intravitreal injection: implications for the cataract surgeon.  J Cataract Refract Surg. 2011;  37 1364
    Google Scholar
  • 24 Klein R, Klein B E K, Tomany S C et al. Association of emphysema, gout, and inflammatory markers with long-term incidence of age-related maculopathy.  Arch Ophthalmol. 2003a;  121 674-678
    Google Scholar
  • 25 Klein R, Klein B E K, Tomany S C et al. The association of cardiovascular disease with the long-term incidence of age-related maculopathy: the Beaver Dam Eye Study.  Ophthalmology. 2003b;  110 1273-1280
    Google Scholar
  • 26 Klein R, Klein B E K, Wong T Y et al. The association of cataract and cataract surgery with the long-term incidence of age-related maculopathy: the Beaver Dam eye study.  Arch Ophthalmol. 2002;  120 1551-1558
    Google Scholar
  • 27 Lundström M, Brege K G, Florén I et al. Cataract surgery and quality of life in patients with age related macular degeneration.  Br J Ophthalmol. 2002;  86 1330-1335
    Google Scholar
  • 28 Maltzman B A, Mulvihill M N, Greenbaum A. Senile macular degeneration and risk factors: a case-control study.  Ann Ophthalmol. 1979;  11 1197-1201
    Google Scholar
  • 29 Mayer M J, Spiegler S J, Ward B et al. Mid-frequency loss of foveal flicker sensitivity in early stages of age-related maculopathy.  Invest Ophthalmol Vis Sci. 1992;  33 3136-3142
    Google Scholar
  • 30 Michaelis J. Einführung von präventiven Maßnahmen: Epidemiologie, Kausalität und Nutzen-Risiko-Abwägungen.  Dtsch Ärztebl. 1996;  93 A-3278-A-3279
    Google Scholar
  • 31 Mönestam E I, Lundqvist B. Extended long-term outcomes of cataract surgery.  Acta Ophthalmol. 2011;  in press; Epub ahead of print Mar 30
    Google Scholar
  • 32 Moss S E, Klein R, Klein B E et al. Alcohol consumption and the 5-year incidence of age-related maculopathy: the Beaver Dam eye study.  Ophthalmology. 1998;  105 789-794
    Google Scholar
  • 33 Pollack A, Marcovich A, Bukelman A et al. Age-related macular degeneration after extracapsular cataract extraction with intraocular lens implantation.  Ophthalmology. 1996;  103 1546-1554
    Google Scholar
  • 34 Rosenfeld P J, Shapiro H, Ehrlich J S et al. Cataract Surgery in Ranibizumab-Treated Patients With Neovascular Age-Related Macular Degeneration From the Phase 3 ANCHOR and MARINA Trials.  Am J Ophthalmol. 2011;  152 793-798
    Google Scholar
  • 35 Saeed M U, Prasad S. Management of cataract caused by inadvertent capsule penetration during intravitreal injection of ranibizumab.  J Cataract Refract Surg. 2009;  35 1857-1859
    Google Scholar
  • 36 Shah S A, Miller K M. Explantation of an AcrySof Natural intraocular lens because of a color vision disturbance.  Am J Ophthalmol. 2005;  140 941-942
    Google Scholar
  • 37 Shuttleworth G N, Luhishi E A, Harrad R A. Do patients with age related maculopathy and cataract benefit from cataract surgery?.  Br J Ophthalmol. 1998;  82 611-616
    Google Scholar
  • 38 Sutter F K P, Menghini M, Barthelmes D et al. Is pseudophakia a risk factor for neovascular age-related macular degeneration?.  Invest Ophthalmol Vis Sci. 2007;  48 1472-1475
    Google Scholar
  • 39 Turner P L, Mainster M A. Circadian photoreception: ageing and the eye's important role in systemic health.  Br J Ophthalmol. 2008;  92 1439-1444
    Google Scholar
  • 40 van der Hoeve J. Schädigungen des Auges durch Licht. Senile Linsentrübungen und senile Maculadegeneration.  Graefes Arch Clin Exp Ophthalmol. 1918;  98 49-66
    Google Scholar
  • 41 Vingerling J R, Dielemans I, Bots M L et al. Age-related macular degeneration is associated with atherosclerosis. The Rotterdam Study.  Am J Epidemiol. 1995;  142 404-409
    Google Scholar
  • 42 Wang J J, Klein R, Smith W et al. Cataract surgery and the 5-year incidence of late-stage age-related maculopathy: pooled findings from the Beaver Dam and Blue Mountains eye studies.  Ophthalmology. 2003;  110 1960-1967
    Google Scholar
  • 43 Wegner A, Khoramnia R. Cataract is a self-defence reaction to protect the retina from oxidative damage.  Med Hypotheses. 2011;  76 741-744
    Google Scholar
  • 44 Wirtitsch M G, Schmidinger G, Prskavec M et al. Influence of blue-light-filtering intraocular lenses on color perception and contrast acuity.  Ophthalmology. 2009;  116 39-45
    Google Scholar

Prof. Dr. med. Holger Baatz

Aurelios Augenzentrum Recklinghausen
Johann Wolfgang Goethe-Universität Frankfurt am Main
Klinik für Augenheilkunde

Erlbruch 34–36

45657 Recklinghausen

Theodor-Stern-Kai 7

60590 Frankfurt am Main

Phone: 02361/30 69 7-0

Fax: 02361/30 69 7-199

Email: holger.baatz@augenzentrum.org

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