Biological Effects of C 200 Oak Silkworm Pupae's Hydrophilic Components

Summary

In the liquid contents of oak silkworm pupae a unique antioxidant system occurs. During the calculation of the 50 % inhibition of reactive oxygen species production, it was shown that haemolymph of oak silkworm pupae is more effective than haemolymph of grape snails in the system luminol + HOCl in 200 times, luminol + myeloperoxidase + horseradish H₂O₂ in 200 times, and generation of reactive oxygen species by neutrophils during adhesion in 700 times, and generation of reactive oxygen species by neutrophils during the action of fMet-Leu-Phe in 300 times and the generation of reactive oxygen species by neutrophils during the action of the latex in 4000 times. It was established that a one-month introduction of the C 200 aqueous extract of oak silkworm pupae in rats during reproduction of the metabolic syndrome (by feeding on a high-fat diet by Lieber-De Carli) provided a reduction of insulin resistance by 29.6 %, the concentration of insulin by 26.7 %, glucose concentration by 12 % and weight by 8.9 % compared to the animals that received only a high-fat diet. The results of these studies conclusively confirm the effect of C 200 dilutions of homeopathic remedies and confound skeptical and anti-homeopathic arguments. The results of this scientific work have exceeded all expectations and have global significance for homeopathic science.

Chinese oak silkworm Antheraea pernyi - Antioxidant - Reactive oxygen species - Oxidative stress - Diapause - Insulin resistance - Metabolic syndrome - Luminol - Dilution - Succussion

References

• 1 Denisova S I. Theoretical Foundations of Chinese Oak Silkworm breeding in Belarus. Pl. Minsk: UE Tehnoprint; 2002: 234
• 2 Katin A J, Katina M A. Fundamentals of Homeopathy. Belarusian School. M. Medical Literature; 2010: 368
• 3 Radkevich V A. Ecology of leaf-eating Insects.  Science and Technology. 1980;  239
• 4 Trokoz V A, Aretinskaya T B, Trokoz N V. Method of oak silkworm growing. Patent of Ukraine No. 62561. 2005
• 5 Kirik N N, Aretinskaya T B, Stanilevich V S et al. Oak silkworm cocoons raw (fresh) and air-dried, TU PCT USSR 1964 – 86. Gosplan USSR, Kiev. 
• 6 Trokoz V A, Aretinskaya T B, Trokoz N V. Biologically active products of A. pernyi: aspects of a medical-prophylactic. Abstracts of the second All-Russian conference on oncology and anaesthesiology of domestic animals. Moscow; 2006: 21-28
• 7 Trokoz V A, Lotosh T D, Abramova A B et al. Method of extract obtaining. Author's Certificate USSR, No. 1787439 A1, Ukraine patent 16965. 1997
• 8 Chirkin A A, Kovalenko E I, Sheybak V M et al. The antioxidant activity of Chinese oak silkworm pupae (Antheraea pernyl G.-M.). Proceedings of EE VSU them. P. M. Masherova 2007. 6: 248-266
• 9 Chirkin A A, Kovalenko E I, Zavodnik I B, Parshonok D I. Antioxidant activity of hemolymph oak silkworm pupae in the modeling of oxidative stress in human cells: ecological anthropology. Minsk: Publishing “Belarusski kamitet” Dzetsi Charnobylya; 2009: 61-65
• 10 Kovalenko E I, Parshonok D I, Vyazov E V, Chirkin A A. Changes in the activity of neutrophils in human blood during the interaction with components of the liquid contents of oak silkworm pupae in vitro.  International Journal of Immunopathology, Allergology, Infectiology. 2009;  3 21-26
• 11 Endler P C, Pongratz W, van Wijk R, Kastberger G, Haidvogl M. Effects of highly diluted succussed thyroxin on metamorphosis of highland frogs.  Berlin J Res Hom. 1991;  1 151-160
• 12 Graunke H, Endler P C, Scherer-Pongratz W et al. Treatment of lowland frogs from the spawn stage with homeopathically prepared thyroxin (10–30).  ScientificWorldJournal. 2007;  7 1697-1702