Semin Reprod Med 2011; 29(1): 055-060
DOI: 10.1055/s-0030-1268704
© Thieme Medical Publishers

Uterus Transplantation: On the Edge

Giuseppe Del Priore1 , Stefan Schlatt2 , Robert Wagner3 , Elena Reynoso4 , Jeanetta Malanowska-Stega4
  • 1Indiana University, Simon Cancer Center, Department of Ob-Gyn, Indianapolis, Indiana
  • 2Centre of Reproductive Medicine and Andrology, University Münster, Münster, Germany
  • 3Chief of Surgical Veterinary Services, University of Pittsburg, Pittsburg, Pennsylvania
  • 4New York Downtown Hospital – New York Presbyterian Healthcare, New York, New York
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Publication History

Publication Date:
04 January 2011 (online)

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ABSTRACT

Uterus transplantation for absolute uterus factor infertility is moving closer to human trials. The indication for uterus transplantation is evident as is its potential to ameliorate the social and personal burdens of these patients. The extensive collaborative research efforts between animal works, advancements in transplantation medicine, and immune suppression have culminated in demonstrating its apparent feasibility. As for the concerns regarding its risk, in perspective it is similar to other high-risk pregnancies. Moving uterus transplantation toward clinical applications obviously will require a continued commitment of research and support.

REFERENCES

Giuseppe Del PrioreM.D. M.P.H. 

Indiana University, Simon Cancer Center

535 Barnhill Drive, Room RT 433, Indianapolis, IN 46202

Email: gdelprio@IUPUI.edu