pferde spiegel 2010; 13(4): 154-160
DOI: 10.1055/s-0030-1250467
fachspiegel

© Enke Verlag in MVS Medizinverlage Stuttgart GmbH & Co. KG

Management von Zwillingsträchtigkeiten bei der Stute

Management of equine twin pregnanciesJutta Klewitz, Frauke Uhlendorf, Florian Geburek, Florian Ortgies, Harald Sieme
Further Information

Publication History

Publication Date:
15 December 2010 (online)

Summary

Twin pregnancies in the mare usually lead to abortion, stillbirth or the delivery of weak foals. For this reason different reduction methods are applied in studfarm practice. During the early pregnancy manual crushing of one embryo is the most successful therapy with high survival rates of the remaining embryo. Depending on gestation length and the localisation of twins dietary manipulation, transvaginal ultrasound-guided twin reduction, surgical removal of one conceptus, craniocervical dislocation, placenta ablation, transabdominal ultrasound-guided twin reduction and induction of abortion are used to reduce twin pregnancies. This review article describes the factors influencing the occurrence of twins in the mare, the procedures and the success rates of different reduction methods.

Literaturverzeichnis als PDF

Literatur

  • 1 Allen W R, Brown L, Wright M, Wilsher S. Reproductive efficiency of Flatrace and National Hunt Thoroughbred mares and stallions in England.  Equine Vet J. 2007;  39 438-445
  • 2 Becker F, Göllnitz K, Kleinpeter A, Neubauer J, Keindorf H J, Nürnberg G, Kanitz W. Untersuchungen zur transvaginalen ultrasonographisch geleiteten Reduktion von Zwillingsträchtigkeiten bei der Stute.  Pferdeheilkunde. 2006;  22 165-168
  • 3 Bowman T. Ultrasonic diagnosis and management of early twins in the mare.  Proc Am Ass Equine Practnrs. 1986;  32 35-43
  • 4 Bracher V, Parlevliet J M, Pieterse M C, Vos P L A M, Wiemer P, Taverne M A M, Colenbrander B. Transvaginal ultrasound-guided twin reduction in the mare.  Vet Rec. 1993;  133 478-479
  • 5 Davies Morel M C, Newcombe J R. The efficacy of different hCG dose rates and the effect of hCG treatment on ovarian activity: ovulation, multiple ovulation, pregnancy, multiple pregnancy, synchrony of multiple ovulation; in the mare.  Anim Reprod Sci. 2008;  109 189-199
  • 6 Frazer G S. Twins.. Current Therapy in Equine Medicine 5.. Philadelphia: W. B. Saunders; 2003: 245-248
  • 7 Giles R, Donahue J, Hong C, Tuttle P, Petrites-Murphy M, Poonacha K, Roberts A, Tramontin R, Smith B, Swerczek T. Causes of abortion, stillbirth and perinatal death in horses: 3527 cases(1986–1991).  J Am Vet Med Assoc. 1993;  8 1170-1175
  • 8 Ginther O J. Reproductive Biology in the Mare.. Cross Plains (WI): Equiservices; 1979
  • 9 Ginther O J. Twinning in mares: a review of recent studies.  J Equine Vet Sci. 1982;  2 127-135
  • 10 Ginther O J. Effect of reproductive status on twinning and on side of ovulation and embryo attachment in mares.  Theriogenology. 1983;  20 383-395
  • 11 Ginther O J. Postfixation embryo reduction in unilateral and bilateral twins in mares.  Theriogenology. 1984;  22 213-223
  • 12 Ginther O J. The nature of embryo reductions in mares with twin conceptuses: deprivation hypothesis.  Am J Vet Res. 1989;  50 45-53
  • 13 Ginther O J, Douglas R H, Lawrence J R. Twinning in mares: a survey of veterinarians ans analyses of theriogenology records.  Theriogenology. 1982;  18 333-347
  • 14 Ginther O J, Griffin P. Natural outcome and ultrasonic identification of equine fetal twins.  Theriogenology. 1994;  41 1193-1199
  • 15 Govaere J L J, Hoogewijs M K, De Schauwer C, Dewulf J, De Kruif A. Transvaginal ultrasound-guided aspiration of unilateral twin gestation in the mare.  Equine Vet J. 2008;  40 521-522
  • 16 Govaere J J L, Hoogewijs M K, De Schauwer C, Van Zeveren A, Smits K, Cornillie P, De Kruif A. An abortion of monozygotic twins in a Warmblood mare.  Reprod Dom Anim. 2009;  44 852-854
  • 17 Hoffmann B, Leiser R, Schuler G. Physiologie und Anatomie der Trächtigkeit, Trächtigkeitsdiagnostik.. Reproduktionsmedizin beim Pferd.. Stuttgart: Parey; 2009: 125-154
  • 18 Jeffcott L B, Whitwell K W. Twinning as a cause of neonatal loss in the Thoroughbred.  J Comp Pathol. 1973;  83 91-105
  • 19 Jonker F, Parlevliet J, Pycock J, Vos P. Twin reduction in sixteen mares by transvaginal ultrasound-guided puncture of the embryonic vesicle. Proc Brit Eq Vet Assoc Annual Congress 1995
  • 20 Klewitz J, Heberling A, Ortgies F, Sieme H. Erfolgsraten nach Zwillingsreduktion mittels transvaginal-ultraschallgeleiteter Fruchtwasseraspiration und transrektaler craniocervikaler Dislokation. 21. Arbeitstagung FG Pferdekrankheiten 2010
  • 21 Klewitz J, Heberling A, Ortgies F, Sieme H. Erfolgsraten nach transvaginal-ultraschallgeleiteter Fruchtwasseraspiration und fetaler Punktion bei der Stute.  Pferdeheilkunde. 2010;  im Druck
  • 22 LeBlanc M, Lopate C, Knottenbelt D. Pregnancy.. Equine Stud Farm Medicine and Surgery.. London: W. B. Saunders; 2003: 263
  • 23 MacPherson M I, Reimers J M. Twin reduction in the mare: current options.  Anim Reprod Sci. 2000;  60–61 233-244
  • 24 Mari G, Iacono E, Merlo B, Castagnetti C. Reduction of twin pregnancy in the mare by transvaginal ultrasound-guided aspiration.  Reprod Domest Anim. 2004;  39 434-437
  • 25 McKinnon A O. Twin reduction techniques.. Current Therapy in Equine Reproduction.. St. Louis: W. B. Saunders; 2007: 357-373
  • 26 McKinnon A O, Rantanen N. Twins.. Equine Diagnostic Ultrasonography.. Baltimore: Williams & Wilkins; 1998: 141-156
  • 27 Meadows S J, Binns M M, Newcombe J R, Thompson C J, Rossdale P D. Identical triplets in a Thoroughbred mare.  Equine Vet J. 1995;  27 394-397
  • 28 Merkt H, Jungnickel S, Klug E. Reduction of early twin pregnancy to a single pregnancy in the mare by dietetic means.  J Reprod Fertil Suppl. 1982;  32 451-452
  • 29 Merkt H, Jöchle W. Abortions and twin pregnancies in the Thoroughbreds: rate of occurrence, treatments and prevention.  J Equine Vet Sci. 1993;  13 690-694
  • 30 Merkt H, Jöchle W. More twin pregnancies as seasons progresses.  J Equine Vet Sci. 1999;  15 614-617
  • 31 Morris L H A, Greenwood R E S, Allen W R. Transvaginal ultrasound-guided reduction of twin conceptusses in the mare.  Proc Int Conf Equine Reprod. 1999;  15 614-617
  • 32 Pascoe R R. Methods for the treatment of twin pregnancy in the mare.  Equine Vet J. 1983;  15 40-42
  • 33 Pascoe D R, Pascoe R R, Hughes J P, Stabenfeld G H, Kindahl H. Management of twin conceptusses by manual embryonic reduction: comparison of two techniques and three hormone treatments.  Am J Vet Res. 1987;  48 1594-1599
  • 34 Pascoe D R, Stover S M. Effect of surgical manipulation, placental fluid and flunixin meglumine on fetal viability and prostaglandin F release on the gravid uterus of mares.  Am J Vet Res. 1989;  50 1505-1511
  • 35 Platt H. Etiological aspects of perinatal mortality in the Thoroughbred.  Equine Vet J. 1983;  5 116-120
  • 36 Rantanen N. Ultrasound guided fetal cardiac puncture for twin reduction in mares.  Proc Am Med Soc Therio. 1990;  64-65
  • 37 Rantanen N W, Kincaid B. Ultrasound guided fetal cardiac puncture. A method of twin reduction in the mare.  Proc Am Assoc Equine Prctnrs. 1988;  34 173-179
  • 38 Ricketts S, Barrelet A, Whitwell K E. Equine abortion.. Reproduction Foaling. Part 2: Fetal and Neonatal Aspects, EVE manual.. Newmarket: Veterinary Journal; 2003: 18-21
  • 39 Riera F L, Roldán J E, Hinrichs K. Patterns of embryo recovery in mares with unilateral and bilateral double ovulations.  Anim Reprod Sci. 2006;  94 398-399
  • 40 Rooney J R. The fetus and foal.. Autopsy of the Horse.. Baltimore: Williams & Wilkins; 1970: 120-134
  • 41 Squires E L, McClain M G, Ginther O J, McKinnon A O. Spontaneus multiple ovulation in the mare and its effects on the incidence of twin embryo collections.  Theriogenology. 1987;  28 609-613
  • 42 Veronesi M C, Battocchio M, Faustini M, Gandini M, Cairoli F. Relationship between pharmacological induction of estrous and/or ovulation and twin pregnancy in the Thoroughbred mares.  Domest Anim Endocr. 2003;  25 133-140
  • 43 Veronesi M C, Faustini M, Villani M, Kindahl H, Galeati G, Batocchio M. Plasma concentrations of 15-Ketodihydro- PGF, cortisol and progesterone during manual twin reduction in Thoroughbred mares.  J Vet Med. 2005;  52 411-415
  • 44 Wolc A, Bresinska A, Szwaczjowski T. Genetic and permanent environmental variability of twinning in Thoroughbred horses estimated via three threshold models.  J Anim Breeding Genetics. 2006;  123 186-190
  • 45 Wolfsdorf K E. Management of postfixation twins in mares.  Vet Clin N Am Practnrs. 2006;  22 713-725
  • 46 Wolfsdorf K E, Rodgerson D, Holder R. How to manually reduce twins between 60 and 120 days gestation using cranio-cervical dislocation.  Proc Am Ass Equine Practnrs. 2005;  51 284-287

Dr. Jutta Klewitz

Klinik für Pferde
Reproduktionsmedizinische Einheit der Kliniken
Stiftung Tierärztliche Hochschule Hannover

Bünteweg 15

30559 Hannover

Email: jutta.klewitz@tiho-hannover.de

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