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DOI: 10.1055/s-0029-1245811
© Georg Thieme Verlag KG Stuttgart · New York
Die Alzheimer-Demenz mit präsenilem Beginn – Besonderheiten in Diagnostik, Therapie und Management
Early Onset Alzheimer’s Disease – Diagnosis, Therapy and ManagementPublication History
Publication Date:
10 March 2011 (online)

Zusammenfassung
In der vorliegenden Arbeit werden die Besonderheiten der Diagnostik, der Therapie und der Betreuung von Patienten mit präseniler, vor dem 65. Lebensjahr beginnender Alzheimer-Demenz beschrieben und anhand von zwei Fallbeispielen illustriert. Der aktuelle Kenntnisstand bezüglich der ätiologischen, pathophysiologischen, klinischen und bildmorphologischen Besonderheiten wird dargestellt. Das diagnostische Procedere und differenzialdiagnostische Überlegungen werden aufgezeigt. Die Wichtigkeit der Aufklärung über die Erkrankung wird betont und insbesondere nichtmedikamentöse Therapiemaßnahmen und Unterstützungsmöglichkeiten werden vorgestellt.
Abstract
This work describes the characteristics of diagnosis, therapy and management of patients with presenile, early onset Alzheimer’s disease on the basis of two case reports. The current state of knowledge regarding aetiological, pathophysiological and clinical characteristics is presented. The diagnostic procedures and differential diagnostic considerations are illustrated. The importance of the disclosure of the diagnosis is highlighted. Options for non-cognitive treatment, counselling and support are described.
Schlüsselwörter
präsenile Alzheimer-Demenz - senile Alzheimer-Demenz - Diagnose - nichtmedikamentöse Therapie - präsenile Demenz
Keywords
early onset Alzheimer’s disease - late onset Alzheimer’s disease - diagnosis - non-pharmaceutical therapy - presenile dementia
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Dr. Janine Diehl-Schmid
Psychiatrische Klinik TU München
Ismaninger Str. 22
81675 München
Email: janine.schmid@lrz.tum.de