Zusammenfassung
Schlafgebundene Epilepsien und Parasomnien interagieren und werden durch den Schlaf-Wach-Rhythmus
gesteuert. Der Schlaf-Wach-Rhythmus ist bei beiden Krankheitsbildern in ähnlicher
Weise durch vermehrte Arousal unterschiedlicher Ursachen gestört und unterhält die
Bereitschaft für nächtliche Ereignisse. Epilepsien und Parasomnien scheinen häufig
über die gleichen Hirnzentren und Bahnen gesteuert zu werden; dem gemeinsamen Auftreten
sollte daher größere Aufmerksamkeit gewidmet werden. Die Diagnostik erfordert in wenigen
Fällen eine Langzeit-Polysomnographie mit Epilepsie-schaltung. Die Differenzierung
der Krankheitsbilder der DOA und Epilepsien erfordert zur weiteren Erforschung eine
Bildgebung mit intelligenten Algorithmen und eine detaillierte Analyse der polysomnografischen
Mikrostruktur.
Abstract
Sleep-associated epilepsies and parasomnias interact with each other. They are controlled
by the sleep wake rhythm. In both clincial entities the sleep wake rhythm is similarly
disturbed by increased arousal due to different causes sustaining the potential for
nocturnal motor events. Epilepsies and parasomnias seem to be controlled by the same
brain centres and pathways; therefore more attention should be paid to their concomitant
occurrence. In a few cases the diagnosis requires long-term polysomnography with epilepsy
circuits. The further differentiation of the disorders of arousal (DOA) and epilepsies
requires further research and imaging with intelligent algorithms and a detailed analysis
of the polysomnographic microstructures.
Schlüsselwörter
Schlaf-Wach-Rhythmus - DOA - schlafgebundene Bewegungen - Epilepsie - Polysomnografie
Key words
sleep wake rhythm - disorders of arousal - sleep related movements - epilepsy - polysomnography
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Korrespondenzadresse
Prof. Dr med G. Mayer
Hephata Klinik
Neurologische Klinik
Schimmelpfengstr 2
34613 Schwalmstadt-Treysa
Email: geert.mayer@hephata.com
