Semin Musculoskelet Radiol 2026; 30(01): 033-042
DOI: 10.1055/a-2732-7610
Review Article

Management of Bone Marrow Edema with Interventional Radiology: When and How

Authors

  • Francesco Arrigoni

    1   Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
  • Thomas Le Corroller

    2   Radiology Department, APHM, Marseille, France
    3   Aix Marseille University, CNRS, ISM UMR 7287, Marseille, France
  • Julia Daffinà

    4   Department of Diagnostic and Teleradiology, ASL Rieti, Rieti, Italy
  • Luigi Zugaro

    5   Radiology Department, San Filippo e Nicola Hospital, Avezzano, Italy
  • Carmine Zoccali

    6   Oncological Orthopedics University ‘‘Sapienza’' of Rome, Rome, Italy
    7   Oncological Orthopedics Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy
  • Ernesto Di Cesare

    1   Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
  • Antonio Barile

    1   Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy
  • Carlo Masciocchi

    1   Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy

Abstract

Bone marrow edema, a typical and exclusive finding of magnetic resonance imaging, is a characteristic of multiple pathologies. There is still no consensus about its origin and histologic characteristics. In this article, we describe six causes of bone edema based on pathophysiologic characteristics: traumatic, infectious, inflammatory, degenerative, tumoral, and neuromediated. For each of them, we explain both the diagnostic and therapeutic role of interventional radiology. The fundamental importance of bone biopsy in characterizing the lesions associated with bone edema is also reviewed.



Publication History

Received: 04 July 2025

Accepted: 16 October 2025

Article published online:
20 February 2026

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