Author commentary on Simone Rocchetto et al.

Simone Rocchetto et al. Added value of a balloon-based mucosal exposure device in computer-aided detection-assisted colonoscopy: a randomized controlled trial (COMBAT study)

The effectiveness of a balloon-based mucosal exposure device during colonoscopy with computer-aided detection (CADe) was evaluated in this multicenter randomized trial, involving 644 patients with positive fecal immunochemical tests. No added benefit from using the device was shown, either in number of patients identified with findings deem„ed high risk according to ESGE criteria, or in adenoma detection rate, suggesting that the CADe system alone may already maximize detection.

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Publication History

Article published online:
27 November 2025