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DOI: 10.1055/a-2654-3327
Ninety-Day Complications Following Total Hip Arthroplasty with Computer Navigation versus Conventional Techniques
Abstract
Background
Computer navigation is associated with improved limb alignment and implant position in total joint arthroplasty. While it is commonly used in total knee arthroplasty, adoption in the setting of total hip arthroplasty (THA) has been slower. Further, the literature is equivocal on whether computer navigation improves outcomes. The aim of this study was to assess the impact of computer navigation on outcomes in the setting of THA.
Materials and Methods
This was a retrospective cohort study. The National Readmissions Database, from 2016 to 2020, was queried via International Classification of Diseases, Tenth Revision (ICD-10) codes for all patients undergoing THA. To compare outcomes between conventional and computer-navigated THA, propensity score matching was used. In the matched cohort, logistic regression was applied to evaluate postoperative complications, while negative binomial regression was used to analyze readmissions, reoperations, and discharge disposition. Gamma regression with a log-link function was utilized to assess hospital charges and length of stay.
Results
We identified a total of 1,191,362 patients undergoing primary THA. After successful matching, there were 12,918 patients in each cohort. Computer navigation was associated with increased blood transfusions (odds ratio [OR] 2.72; p < 0.001). There were no significant differences in all-cause medical complications (p = 0.123). Computer-navigated procedures were associated with significantly reduced 90-day readmission (OR 0.85; p = 0.028); however, total charges were greater (OR 1.31; p = 0.002).
Conclusion
We found that computer-navigated THA was significantly more expensive but had reduced short-term readmission following surgery. While there were increased odds of blood transfusion, computer navigation may still be safe and beneficial in appropriately selected patients.
Hip osteoarthritis is a leading cause of disability, and due to an aging population, it is becoming more common.[1] [2] [3] [4] Total hip arthroplasty (THA) is the definitive cure for end-stage osteoarthritis and generally results in high patient satisfaction; however, as with any surgery, there is potential for devastating complications.[5] [6] Implant positioning may be a modifiable factor in preventing these complications and subsequent poor outcomes. The position of the cup and stem prosthetics is thought to directly correlate to the risk of dislocation, leg length discrepancy, articular wear, impingement, and edge-loading, all of which can lead to hardware failure and the need for revision surgery.[7] [8]
Since the 1990s, multiple methods have emerged that attempt to reduce the variability of hip prosthetic placement, such as robotic-assisted and computer-navigated surgery.[9] [10] These advancements may become increasingly important as surgeons move towards less invasive, tissue-preserving techniques that make visualization and precise placement of the implant more difficult.[7] [10]
Computer-navigated THA has consistently shown to increase the accuracy of cup positioning and stem placement.[11] [12] [13] [14] [15] However, as the technique has potential pitfalls when compared to conventional THA, such as increased costs and longer time in the operating room,[16] [17] [18] it is important to determine if it translates to better outcomes, clinically. This study aimed to evaluate short-term medical, surgical, and orthopedic-specific outcomes of THA performed using computer navigation compared to conventional techniques.
Materials and Methods
Data Source and Patient Identification
This retrospective cohort study utilized the Nationwide Readmission Database (NRD), Healthcare Cost and Utilization Project (HCUP), Agency for Healthcare Research and Quality (AHRQ), from 2016 to 2020. The NRD is a national database that includes discharge and readmission information, covering approximately 32 million discharges, or 60.8% of all hospitalizations.[19] It links hospitalization records and patient discharge data within a single calendar year, enabling the evaluation of patient outcomes over time.
With the database, International Classification of Diseases, Tenth Revision, Clinical Modification/Procedure Coding System (ICD-10) codes were utilized to identify all adult patients undergoing THA. We then identified the subset of this population who underwent a THA with computer navigation using ICD-10 procedure codes. As the NRD tracks patients for a single calendar year, we included only those who underwent surgery between January 1 and September 30 to ensure the ability to evaluate outcomes for at least 90 days postoperatively.
Preoperative Variables Collected
We collected several preoperative variables, including patient demographics such as sex, age, household income level, and insurance status. Additionally, using ICD-10 codes, we calculated a weighted modified Elixhauser Comorbidity Index score to summarize each patient's overall comorbidity burden.[20] This index has been validated as a strong predictor of outcomes in total joint arthroplasty.[21]
Propensity Score Matching
To minimize confounding and create balanced comparison groups, propensity score matching was used. The propensity scores were generated through a logistic regression model that included age, Elixhauser Comorbidity Index, sex, socioeconomic status, and insurance status as covariates. Patients who underwent computer-navigated THA were matched 1:1 to those who underwent conventional THA using nearest-neighbor matching without replacement, ensuring a caliper width of 0.2 of the standard deviation of the logit of the propensity score ([Fig. 1]).


Postoperative Outcomes Assessed
With respect to outcomes, we assessed both postoperative complications and hospital-associated outcomes. Complications assessed included both medical and surgical complications. Medical complications include respiratory failure, pulmonary embolism, pneumonia, cardiac arrest, heart failure, myocardial infarction, deep vein thrombosis, acute kidney injury, urological infections, stroke, plegia and paresis, osteomyelitis, and sepsis. Surgical complications include wound disruption, postoperative infection, joint infections, dislocations, periprosthetic fracture, blood transfusion, postoperative neurological complications, postoperative vascular complications, and postoperative shock. Hospital-associated outcomes include mortality, 90-day readmission, 90-day reoperation, length of hospital stay (LOS), discharge disposition (discharge to home is a routine discharge, while non-home discharges were recorded as an adverse discharge disposition), and total charges.
Data Analyses
To ensure the validity of our analysis, we verified that the assumptions for valid logistic and linear regression models were satisfied. For logistic regression, we confirmed that the dependent variable was dichotomous, there was no multicollinearity among predictor variables, and the logit was linear for each continuous independent variable. For linear regression, we assessed the normality of residuals, the independence of observations, the homoscedasticity of residuals, and the linearity of the relationship between each independent variable and the dependent variable.
Categorical results are reported as counts with column percentages. Continuous data are reported as means and standard deviations, with standard errors given where appropriate. Comparison of normally distributed data was performed with independent sample t tests. For non-normally distributed data, the Wilcoxon rank-sum test was performed. Categorical variables were assessed with Fisher's exact test or chi-square test with Rao-Scott second order correction. Where applicable, residuals were assessed for normal distribution and no multicollinearity was observed.
In the matched cohort, logistic regression was applied to evaluate postoperative complications, while negative binomial regression was used to analyze readmissions, reoperations, and discharge disposition. Gamma regression with a log-link function was utilized to assess total hospital charges and length of stay. Confidence intervals were set to 95%, and p-values of 0.05 or less were considered significant. R Foundation for Statistical Computing software version 4.3.1 was used for all analyses.
No Institutional Review Board (IRB) approval was required for this study; the IRB exemption number is 20230793NRR. This study did not require informed consent.
Results
Demographics
We identified a total of 1,191,362 patients undergoing primary THA. About 1,170,427 (98.24%) underwent a conventional, unassisted procedure, while 20,935 (1.76%) underwent computer navigation. Postmatch, there were 12,918 patients in each cohort. The mean age was 66.20 (SD 10.44), and 14,894 (58%) were women. Full demographics, with counts and proportions prematch and postmatch can be seen in [Tables 1] and [2].
Demographics |
Overall N = 1,191,362[a] |
Conventional N = 1,170,427[a] |
Computer-navigated N = 20,935[a] |
p-Value[b] |
---|---|---|---|---|
Age (years) |
65.95 (10.75) |
65.95 (10.76) |
66.09 (10.51) |
0.3 |
Age category (years) |
0.042 |
|||
< 50 |
77,903 (6.5%) |
76,604 (6.5%) |
1,300 (6.2%) |
|
50–64 |
424,776 (36%) |
417,363 (36%) |
7,413 (35%) |
|
65–79 |
570,422 (48%) |
560,171 48%) |
10,251 (49%) |
|
≥ 80 |
118,261 (9.9%) |
116,289 (9.9%) |
1,971 (9.4%) |
|
Gender |
0.001 |
|||
Female |
664,844 (56%) |
652,853 (56%) |
11,991 (57%) |
|
Male |
526,517 (44%) |
517,574 (44%) |
8,944 (43%) |
|
Household income by zip code |
<0.001 |
|||
0–25th percentile |
229,594 (19%) |
226,564 (19%) |
3,030 (14%) |
|
26th–50th percentile |
318,392 (27%) |
313,265 (27%) |
5,127 (24%) |
|
51st–75th percentile |
332,557 (28%) |
327,494 (28%) |
5,063 (24%) |
|
76th–100th percentile |
310,817 (26%) |
303,102 (26%) |
7,715 (37%) |
|
Payer |
<0.001 |
|||
Medicaid |
52,942 (4.4%) |
52,055 (4.4%) |
887 (4.2%) |
|
Medicare |
671,443 (56%) |
660,070 (56%) |
11,373 (54%) |
|
Other |
30,953 (2.6%) |
30,541 (2.6%) |
412 (2.0%) |
|
Private insurance |
428,731 (36%) |
420,553 (36%) |
8,177 (39%) |
|
Self-pay |
7,294 (0.6%) |
7,207 (0.6%) |
87 (0.4%) |
|
Time to procedure |
0.00 (2.84) |
0.00 (2.86) |
−0.02 (1.42) |
<0.001 |
Length of stay |
2.00 (2.05) |
2.00 (2.06) |
1.66 (1.56) |
<0.001 |
Total charge |
62,546.46 (40,326.54) |
62,198.56 (40,071.61) |
81,996.23 (48,859.31) |
<0.001 |
Discharge disposition |
<0.001 |
|||
Adverse discharge |
2,358 (0.2%) |
2,325 (0.2%) |
34 (0.2%) |
|
Home discharge with care |
531,917 (45%) |
520,572 (44%) |
11,345 (54%) |
|
Routine discharge |
517,598 (43%) |
509,578 (44%) |
8,020 (38%) |
|
Transfer to a skilled facility |
139,462 (12%) |
137,925 (12%) |
1,537 (7.3%) |
|
Elixhauser Comorbidity Index |
<0.001 |
|||
0 |
305,336 (26%) |
299,463 (26%) |
5,873 (28%) |
|
1–2 |
564,521 (47%) |
554,772 (47%) |
9,749 (47%) |
|
3–4 |
99,882 (8.4%) |
98,222 (8.4%) |
1,660 (7.9%) |
|
5+ |
221,623 (19%) |
217,970 (19%) |
3,653 (17%) |
|
90-day readmission |
41,102 (3.4%) |
40,532 (3.5%) |
570 (2.7%) |
<0.001 |
90-day reoperation |
14,146 (1.2%) |
13,937 (1.2%) |
209 (1.0%) |
0.052 |
a Mean (standard deviation); n (percentage).
b Design-based Kruskal–Wallis test; Pearson's χ2: Rao and Scott adjustment.
Demographics |
Overall N = 25,836[a] |
Conventional N = 12,918[a] |
Computer-navigated N = 12,918[a] |
p-Value[b] |
---|---|---|---|---|
Age (years) |
66.20 (10.44) |
66.20 (10.44) |
66.20 (10.45) |
>0.9 |
Age category (years) |
>0.9 |
|||
< 50 |
1,540 (6.0%) |
770 (6.0%) |
770 (6.0%) |
|
50–64 |
9,104 (35%) |
4,552 (35%) |
4,552 (35%) |
|
65–79 |
12,738 (49%) |
6,369 (49%) |
6,369 (49%) |
|
≥ 80 |
2,454 (9.5%) |
1,227 (9.5%) |
1,227 (9.5%) |
|
Gender |
>0.9 |
|||
Female |
14,894 (58%) |
7,447 (58%) |
7,447 (58%) |
|
Male |
10,942 (42%) |
5,471 (42%) |
5,471 (42%) |
|
Household income by zip code |
>0.9 |
|||
0–25th percentile |
3,468 (13%) |
1,734 (13%) |
1,734 (13%) |
|
26th–50th percentile |
5,618 (22%) |
2,809 (22%) |
2,809 (22%) |
|
51st–75th percentile |
6,120 (24%) |
3,060 (24%) |
3,060 (24%) |
|
76th–100th percentile |
10,630 (41%) |
5,315 (41%) |
5,315 (41%) |
|
Payer |
>0.9 |
|||
Medicaid |
1,124 (4.4%) |
562 (4.4%) |
562 (4.4%) |
|
Medicare |
13,988 (54%) |
6,994 (54%) |
6,994 (54%) |
|
Other |
494 (1.9%) |
247 (1.9%) |
247 (1.9%) |
|
Private insurance |
10,130 (39%) |
5,065 (39%) |
5,065 (39%) |
|
Self-pay |
100 (0.4%) |
50 (0.4%) |
50 (0.4%) |
|
Length of stay |
1.75 (1.92) |
1.83 (2.21) |
1.67 (1.57) |
<0.001 |
Total charge |
75,753.97 (47,512.12) |
66,175.15 (41,768.64) |
85,332.80 (50,860.95) |
<0.001 |
Discharge disposition |
||||
Adverse discharge |
46 (0.2%) |
24 (0.2%) |
22 (0.2%) |
|
Home discharge with care |
13,345 (52%) |
6,073 (47%) |
7,272 (56%) |
|
Routine discharge |
10,196 (39%) |
5,529 (43%) |
4,667 (36%) |
|
Transfer to a skilled facility |
2,248 (8.7%) |
1,291 (10.0%) |
957 (7.4%) |
|
Elixhauser Comorbidity Index |
>0.9 |
|||
0 |
7,338 (28%) |
3,669 (28%) |
3,669 (28%) |
|
1–2 |
12,064 (47%) |
6,032 (47%) |
6,032 (47%) |
|
3–4 |
2,052 (7.9%) |
1,026 (7.9%) |
1,026 (7.9%) |
|
5+ |
4,382 (17%) |
2,191 (17%) |
2,191 (17%) |
|
90-day readmission |
777 (3.0%) |
435 (3.4%) |
342 (2.6%) |
<0.001 |
90-day reoperation |
284 (1.1%) |
156 (1.2%) |
128 (1.0%) |
0.095 |
a Mean (standard deviation); n (percentage).
b Wilcoxon rank-sum test. Pearson's chi-square test.
Medical and Surgical Complications
We found that patients in the computer-navigated cohort did not have a significant difference in all-cause medical complications (odds ratio [OR] 0.92 [95% CI 0.83–1.02]; p = 0.123). However, they had reduced odds of respiratory failure (OR 0.70 [95% CI 0.56–0.89]; p = 0.003) and pneumonia (OR 0.71 [95% CI 0.53–0.95]; p = 0.02). Patients in the computer-navigated cohort had increased all-cause surgical complications (OR 1.92 [95% CI 1.34–2.75]; p < 0.001), specifically blood transfusions (OR 2.72 [95% CI 1.78–4.18]; p < 0.001). There was no significant difference between any other surgical complications evaluated. We found no difference in rates of dislocation (p = 0.102), joint infection (p = 0.366), postoperative infection (p = 0.447), or periprosthetic fracture (p = 0.378). Results of univariate analysis, and counts and proportions prematch and postmatch, can be seen in [Tables 3] and [4]. Results of multivariate analysis can be seen in [Fig. 2].


Characteristic |
Overall N = 1,191,362[a] |
Conventional N = 1,170,427[a] |
Computer-navigated N = 20,935[a] |
p-Value[b] |
---|---|---|---|---|
Medical complications |
103,857 (8.7%) |
102,282 (8.7%) |
1,575 (7.5%) |
0.018 |
Respiratory failure |
15,152 (1.3%) |
14,977 (1.3%) |
174 (0.8%) |
<0.001 |
Pulmonary embolism |
5,146 (0.4%) |
5,059 (0.4%) |
87 (0.4%) |
0.8 |
Pneumonia |
9,652 (0.8%) |
9,543 (0.8%) |
109 (0.5%) |
0.002 |
Cardiac arrest |
979 (<0.1%) |
965 (<0.1%) |
14 (<0.1%) |
0.6 |
Heart failure |
40,746 (3.4%) |
40,085 (3.4%) |
661 (3.2%) |
0.4 |
Myocardial infarction |
5,099 (0.4%) |
5,023 (0.4%) |
76 (0.4%) |
0.3 |
Transfusion |
26,762 (2.2%) |
25,753 (2.2%) |
1,009 (4.8%) |
<0.001 |
Deep vein thrombosis |
5,010 (0.4%) |
4,947 (0.4%) |
64 (0.3%) |
0.041 |
Acute kidney disease |
33,198 (2.8%) |
32,733 (2.8%) |
464 (2.2%) |
0.005 |
Urological infections |
22,594 (1.9%) |
22,265 (1.9%) |
328 (1.6%) |
0.024 |
Stroke |
3,115 (0.3%) |
3,082 (0.3%) |
32 (0.2%) |
0.017 |
Plegia and paresis |
2,738 (0.2%) |
2,704 (0.2%) |
34 (0.2%) |
0.11 |
Osteomyelitis |
996 (<0.1%) |
976 (<0.1%) |
20 (<0.1%) |
0.7 |
Sepsis |
12,842 (1.1%) |
12,669 (1.1%) |
173 (0.8%) |
0.009 |
Surgical |
45,684 (3.8%) |
44,431 (3.8%) |
1,253 (6.0%) |
0.001 |
Wound disruption |
4,825 (0.4%) |
4,769 (0.4%) |
56 (0.3%) |
0.013 |
Postop infection |
5,911 (0.5%) |
5,838 (0.5%) |
73 (0.4%) |
0.025 |
Joint infection |
375 (<0.1%) |
371 (<0.1%) |
3 (<0.1%) |
0.3 |
Dislocation |
375 (<0.1%) |
363 (<0.1%) |
12 (<0.1%) |
0.15 |
Periprosthetic fracture |
9,325 (0.8%) |
9,169 (0.8%) |
156 (0.7%) |
0.7 |
Postop shock |
4,300 (0.4%) |
4,246 (0.4%) |
54 (0.3%) |
0.056 |
Postop vascular |
4,439 (0.4%) |
4,389 (0.4%) |
50 (0.2%) |
0.020 |
a n (percentage).
b Pearson's χ2: Rao and Scott adjustment.
Adverse events (postmatch) |
Overall N = 25,836[a] |
Conventional N = 12,918[a] |
Computer-navigated N = 12,918[a] |
p-Value[b] |
---|---|---|---|---|
Medical complications |
2,016 (7.8%) |
1,088 (8.4%) |
928 (7.2%) |
<0.001 |
Respiratory failure |
285 (1.1%) |
182 (1.4%) |
103 (0.8%) |
<0.001 |
Pulmonary embolism |
116 (0.4%) |
65 (0.5%) |
51 (0.4%) |
0.2 |
Pneumonia |
189 (0.7%) |
123 (1.0%) |
66 (0.5%) |
<0.001 |
Cardiac arrest |
14 (<0.1%) |
7 (<0.1%) |
7 (<0.1%) |
>0.9 |
Heart failure |
803 (3.1%) |
421 (3.3%) |
382 (3.0%) |
0.2 |
Myocardial infarction |
105 (0.4%) |
58 (0.4%) |
47 (0.4%) |
0.3 |
Transfusion |
1,004 (3.9%) |
358 (2.8%) |
646 (5.0%) |
<0.001 |
Deep vein thrombosis |
98 (0.4%) |
60 (0.5%) |
38 (0.3%) |
0.026 |
Acute kidney disease |
619 (2.4%) |
344 (2.7%) |
275 (2.1%) |
0.005 |
Urological infections |
413 (1.6%) |
216 (1.7%) |
197 (1.5%) |
0.3 |
Stroke |
48 (0.2%) |
29 (0.2%) |
19 (0.1%) |
0.15 |
Plegia and paresis |
42 (0.2%) |
21 (0.2%) |
21 (0.2%) |
>0.9 |
Osteomyelitis |
23 (<0.1%) |
11 (<0.1%) |
12 (<0.1%) |
0.8 |
Sepsis |
257 (1.0%) |
150 (1.2%) |
107 (0.8%) |
0.007 |
Surgical |
1,390 (5.4%) |
590 (4.6%) |
800 (6.2%) |
<0.001 |
Wound disruption |
86 (0.3%) |
50 (0.4%) |
36 (0.3%) |
0.13 |
Postop infection |
115 (0.4%) |
70 (0.5%) |
45 (0.3%) |
0.019 |
Joint infection |
5 (<0.1%) |
3 (<0.1%) |
2 (<0.1%) |
>0.9 |
Dislocation |
9 (<0.1%) |
2 (<0.1%) |
7 (<0.1%) |
0.2 |
Periprosthetic fracture |
213 (0.8%) |
120 (0.9%) |
93 (0.7%) |
0.063 |
Postop shock |
96 (0.4%) |
61 (0.5%) |
35 (0.3%) |
0.008 |
Postop vascular |
97 (0.4%) |
64 (0.5%) |
33 (0.3%) |
0.002 |
a n (percentage).
b Pearson's chi-square test; Fisher's exact test.
Hospital-Associated Outcomes
With respect to hospital-associated outcomes, the computer-navigated procedure was associated with significantly reduced 90-day readmission (OR 0.85 [95% CI 0.74–0.98]; p = 0.05) and LOS (OR 0.86 [95% CI 0.80–0.92]; p < 0.001); however, total charges were greater (OR 1.31 [95% CI 1.11–1.54]; p = 0.002). The computer-navigated cohort averaged $85,332.80 of total charges, while the conventional cohort averaged $66,175.15. There was no difference in 90-day reoperation (p = 0.906). Results of multivariate analysis for hospital-associated outcomes can be seen in [Fig. 3].


Discussion
This study compared short-term outcomes between conventional and computer-navigated THA. We found that computer-navigated THA had reduced odds of respiratory failure and pneumonia, but increased odds of transfusion. With respect to hospital-associated outcomes, computer-navigated THA had reduced length of stay and 90-day readmission, but there was no difference in 90-day reoperation. We found no difference in dislocation, infection, or periprosthetic fracture between the two procedures. Total charges were significantly greater for the computer-navigated procedure.
Multiple studies report that computer-navigated THA leads to more consistently accurate acetabular component positioning than conventional techniques.[11] [12] [13] [14] A study by Najarian et al. analyzed outcomes of imageless computer navigation compared to conventional THA done by a single surgeon and found that computer navigation reduced positional errors of the acetabular component.[7] Specifically, regarding the degree of abduction and anteversion, the standard deviation and number of “outliers” from ideal placement were significantly decreased with computer-navigated surgery.[7] Moskal and Capps found that, while there was no difference in the mean acetabular abduction and anteversion angles, computer-navigated surgery led to significantly more placements within the “safe zone” than the conventional procedure.[22] “Safe zones,” previously described by Lewinnek et al., are the degree of anteversion and abduction that surgeons aim for when positioning the acetabular component.[23] Whether prosthetic positioning within these designated zones translates to better clinical results remains contested.[7] [24] [25] [26]
The literature is divided regarding whether computer navigation is associated with improved orthopedic-specific outcomes.[12] [27] [28] In a retrospective study comparing the results of conventional, unassisted THA with computer-navigated THA, Bohl et al. found that computer navigation was associated with a lower rate of dislocation and aseptic revision of the acetabular component.[11] Our study, however, did not find any difference in dislocations between the two procedures. Of note, the study by Bohl et al. utilized the 100% Medicare Part A claims dataset, which is limited to adults 65 years of age or older. Considering 42.2% of our dataset was younger than 65, this could have had a significant impact on outcomes. Also, their study had a much longer follow-up of 2 to 3 years, while we only assessed short-term outcomes. Similarly to our study, a meta-analysis by Xu et al. found no difference in postoperative dislocation between computer-navigated and conventional groups, although they did report a significant reduction in the number of cups implanted beyond the safe zone with computer navigation.[12] A randomized control study by Parratte et al. found that, upon evaluation during a 10-year follow-up, patients with computer-navigated versus conventional THA had no difference in functional outcome, acetabular linear wear, or survivorship free from aseptic loosening.[29]
Patients in the computer-navigated cohort had reduced odds of pneumonia and respiratory failure, but there was no difference between the two cohorts for any other medical complications assessed. The computer-navigated cohort also had decreased LOS; while these findings were statistically significant, the difference between the two cohorts was 0.16 days, which is not clinically significant. Finally, the computer-navigated cohort had reduced odds of 90-day readmission. A retrospective database study by Hamilton et al. had similar findings; patients undergoing computer-assisted fluoroscopy-based hip navigation had lower readmission rates at both 90 and 365 days.[30]
We found that the total charges of hospitalization were significantly higher for patients undergoing the computer-navigated procedure; this is in agreement with much of the current literature.[17] [18] [31] Brown et al. found computer navigation to be $1,100 more per case than conventional THA due to increased operating time and costly single-use components.[32] Like our own results, these findings did not include the initial investment required for computer navigation software and equipment. However, we could not assess for any added costs associated with readmission and reoperation, which may result in the two procedures being comparatively cost-neutral. A study by de Palma et al. found that an early dislocation (within 6 weeks) could increase the cost of THA by up to 342%.[33] Importantly, we found no difference in odds of dislocation, suggesting that the benefits of computer navigation may not offset these costs, at least not in the short term.
Along with the added costs of computer-navigated THA, the procedure is also typically longer than conventional surgery and could result in a higher risk of blood transfusion. While we were unable to assess and compare operative times, much of the literature reports that computer navigation leads to more time in the OR.[7] [28] [34] [35] Conversely, a study by Singh et al. found that computer-navigated THA had the shortest operating time when compared to both conventional and robot-assisted THA, although the study was performed at a single institution and did not use propensity matching.[36] Longer duration of surgery has been associated with increased incidence of wound complications, deep surgical site infection, and DVT in THA.[37] [38] Additionally, the added surgical time predisposes patients to higher blood loss and increased odds of receiving a blood transfusion.[39] We found that patients undergoing computer-navigated THA had significantly higher odds of needing a transfusion. These additional risks should be considered when debating whether computer navigation is worth the potential benefits.
Limitations
Our study had multiple limitations. This was a retrospective study and, therefore, had inherent bias. For one, we could not control for where these procedures were taking place, and whether or not the conventional cohort had the same overall resources as the computer-navigated one. The centers that perform high volumes of computer-navigated surgery likely have more institutional volume overall, potentially leading to better outcomes.[40] We also could not control for surgeon experience; there is clearly a learning curve for utilizing computer navigation, and as this is a relatively new technique, our results could be impacted.[7] [41] Additionally, we could not account for surgical approach, which may influence the risk of various complications. Further, we could not assess the actual placement of the prostheses to confirm superior positioning in the computer-navigated cohort, although a great deal of evidence supports our stated assumptions. Another limitation was that, similar to studies on individual implants, studies of technology are product-specific; our data do not account for which individual products may perform better than others. Also, our study relied on ICD-10 codes, which are subject to human error. Finally, we had a short-term follow-up of only 90 days, and as orthopedic-specific complications can occur months to years after THA, we likely did not capture the full array of outcomes.
Conclusion
This study found that computer-navigated THA is associated with greater odds of transfusion, is more costly, and has no difference in orthopedic-specific complications when compared to conventional, unassisted THA. However, computer-navigated THA was associated with reduced odds of pneumonia and respiratory failure, shorter LOS, and reduced odds of 90-day readmission. These findings suggest that, while computer navigation is not the outright superior technique, it may be both safe and beneficial in appropriately selected patients, warranting further consideration of its role in improving THA outcomes. Future research should focus on optimizing the cost-effectiveness of computer navigation in THA and further exploring its long-term benefits in reducing complications and improving patient recovery.
Conflict of Interest
None declared.
-
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Acetabular component positioning in total hip arthroplasty: an evidence-based analysis.
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Niinimäki TT,
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Nousiainen TOP,
Leppilahti JI.
Poor acetabular component orientation increases revision risk in metal-on-metal hip
arthroplasty. J Arthroplasty 2017; 32 (07) 2204-2207
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Sadhu A,
Nam D,
Coobs BR,
Barrack TN,
Nunley RM,
Barrack RL.
Acetabular component position and the risk of dislocation following primary and revision
total hip arthroplasty: A matched cohort analysis. J Arthroplasty 2017; 32 (03) 987-991
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Hernández A,
Lakhani K,
Núñez JH,
Mimendia I,
Pons A,
Barro V.
Can we trust combined anteversion and Lewinnek safe zone to avoid hip prosthesis dislocation?.
J Clin Orthop Trauma 2021; 21: 101562
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Piple AS,
Wang JC,
Hill W.
et al.
Postoperative outcomes and trends in computer-navigated and robotic-assisted total
hip arthroplasty. Hip Int 2024; 34 (05) 569-577
MissingFormLabel
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Confalonieri N,
Manzotti A,
Montironi F,
Pullen C.
Leg length discrepancy, dislocation rate, and offset in total hip replacement using
a short modular stem: navigation vs conventional freehand. Orthopedics 2008 31. (10
Suppl 1): orthosupersite.com/view.asp?rID=35541
MissingFormLabel
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Parratte S,
Ollivier M,
Lunebourg A,
Flecher X,
Argenson J-NA.
No benefit after THA performed with computer-assisted cup placement: 10-year results
of a randomized controlled study. Clin Orthop Relat Res 2016; 474 (10) 2085-2093
MissingFormLabel
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Hamilton WG,
Sershon RA,
Gupta A.
et al.
Readmission rate and healthcare utilization outcomes of computer-assisted fluoroscopy-based
hip navigation versus manual total hip arthroplasty. Expert Rev Med Devices 2023;
20 (09) 779-789
MissingFormLabel
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Korber S,
Antonios JK,
Sivasundaram L.
et al.
Utilization of technology-assisted total hip arthroplasty in the United States from
2005 to 2018. Arthroplast Today 2021; 12: 36-44
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Brown ML,
Reed JD,
Drinkwater CJ.
Imageless computer-assisted versus conventional total hip arthroplasty: one surgeon's
initial experience. J Arthroplasty 2014; 29 (05) 1015-1020
MissingFormLabel
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de Palma L,
Procaccini R,
Soccetti A,
Marinelli M.
Hospital cost of treating early dislocation following hip arthroplasty. Hip Int 2012;
22 (01) 62-67
MissingFormLabel
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Li Y-L,
Jia J,
Wu Q,
Ning G-Z,
Wu Q-L,
Feng S-Q.
Evidence-based computer-navigated total hip arthroplasty: an updated analysis of randomized
controlled trials. Eur J Orthop Surg Traumatol 2014; 24 (04) 531-538
MissingFormLabel
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Aoude AA,
Aldebeyan SA,
Nooh A,
Weber MH,
Tanzer M.
Thirty-day complications of conventional and computer-assisted total knee and total
hip arthroplasty: Analysis of 103,855 patients in the American College of Surgeons
National Surgical Quality Improvement Program Database. J Arthroplasty 2016; 31 (08)
1674-1679
MissingFormLabel
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Singh V,
Realyvasquez J,
Simcox T,
Rozell JC,
Schwarzkopf R,
Davidovitch RI.
Robotics versus navigation versus conventional total hip arthroplasty: does the use
of technology yield superior outcomes?. J Arthroplasty 2021; 36 (08) 2801-2807
MissingFormLabel
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Urquhart DM,
Hanna FS,
Brennan SL.
et al.
Incidence and risk factors for deep surgical site infection after primary total hip
arthroplasty: a systematic review. J Arthroplasty 2010; 25 (08) 1216-22.e1 , 3
MissingFormLabel
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Orland MD,
Lee RY,
Naami EE,
Patetta MJ,
Hussain AK,
Gonzalez MH.
Surgical duration implicated in major postoperative complications in total hip and
total knee arthroplasty: A retrospective cohort study. J Am Acad Orthop Surg Glob
Res Rev 2020; 4 (11) e20.00043
MissingFormLabel
- 39
Ross D,
Erkocak O,
Rasouli MR,
Parvizi J.
Operative time directly correlates with blood loss and need for blood transfusion
in total joint arthroplasty. Arch Bone Jt Surg 2019; 7 (03) 229-234
MissingFormLabel
- 40
Nathens AB,
Jurkovich GJ,
Maier RV.
et al.
Relationship between trauma center volume and outcomes. JAMA 2001; 285 (09) 1164-1171
MissingFormLabel
- 41
Hecht Ii CJ,
Porto JR,
Sanghvi PA,
Homma Y,
Sculco PK,
Kamath AF.
Navigating the learning curve: assessing caseload and comparing outcomes before and
after the learning curve of computer-navigated total hip arthroplasty. J Robot Surg
2024; 18 (01) 104
MissingFormLabel
Address for correspondence
Publication History
Received: 23 January 2025
Accepted: 11 July 2025
Article published online:
01 August 2025
© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA
Blaire Peterson, Travis Kotzur, Aaron Singh, John Parker, Frank Buttacavoli, Chance Moore. Ninety-Day Complications Following Total Hip Arthroplasty with Computer Navigation versus Conventional Techniques. Surg J (N Y) 2025; 11: a26543327.
DOI: 10.1055/a-2654-3327
-
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Petersson IF,
Björk J.
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Current and future impact of osteoarthritis on health care: A population-based study
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Cross M,
Smith E,
Hoy D.
et al.
The global burden of hip and knee osteoarthritis: Estimates from the global burden
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Bierma-Zeinstra S.
Osteoarthritis. Lancet 2019; 393 (10182): 1745-1759
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Porter ML,
Malchau H,
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Hip replacement. Lancet 2018; 392 (10158): 1662-1671
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Sato EH,
Stevenson KL,
Blackburn BE.
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Recovery curves for patient reported outcomes and physical function after total hip
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Najarian BC,
Kilgore JE,
Markel DC.
Evaluation of component positioning in primary total hip arthroplasty using an imageless
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15-21
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Migliorini F,
Cuozzo F,
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Hildebrand F,
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CT-based navigation for total hip arthroplasty: A meta-analysis. Eur J Med Res 2023;
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DiGioia AM,
Jaramaz B,
Blackwell M.
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The Otto Aufranc Award. Image guided navigation system to measure intraoperatively
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Renkawitz T,
Tingart M,
Grifka J,
Sendtner E,
Kalteis T.
Computer-assisted total hip arthroplasty: coding the next generation of navigation
systems for orthopedic surgery. Expert Rev Med Devices 2009; 6 (05) 507-514
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Bohl DD,
Nolte MT,
Ong K,
Lau E,
Calkins TE,
Della Valle CJ.
Computer-assisted navigation is associated with reductions in the rates of dislocation
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Joint Surg Am 2019; 101 (03) 250-256
MissingFormLabel
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Xu K,
Li YM,
Zhang HF,
Wang CG,
Xu YQ,
Li ZJ.
Computer navigation in total hip arthroplasty: A meta-analysis of randomized controlled
trials. Int J Surg 2014; 12 (05) 528-533
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Montgomery BK,
Bala A,
Huddleston III JI,
Goodman SB,
Maloney WJ,
Amanatullah DF.
Computer navigation vs conventional total hip arthroplasty: A Medicare database analysis.
J Arthroplasty 2019; 34 (09) 1994-1998.e1
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Beckmann J,
Stengel D,
Tingart M,
Götz J,
Grifka J,
Lüring C.
Navigated cup implantation in hip arthroplasty. Acta Orthop 2009; 80 (05) 538-544
MissingFormLabel
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Manzotti A,
Cerveri P,
De Momi E,
Pullen C,
Confalonieri N.
Does computer-assisted surgery benefit leg length restoration in total hip replacement?
Navigation versus conventional freehand. Int Orthop 2011; 35 (01) 19-24
MissingFormLabel
- 16
LaValva SM,
Chiu Y-F,
Fowler MJ,
Lyman S,
Carli AV.
Robotics and navigation do not affect the risk of periprosthetic joint infection following
primary total hip arthroplasty: A propensity score-matched cohort analysis. J Bone
Joint Surg Am 2024; 106 (07) 582-589
MissingFormLabel
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Constantinescu DS,
Costello II JP,
Yakkanti RR.
et al.
Varying complication rates and increased costs in technology-assisted total hip arthroplasty
versus conventional instrumentation in 1,372,300 primary total hips. J Arthroplasty
2024; 39 (07) 1771-1776
MissingFormLabel
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Hsiue PP,
Chen CJ,
Villalpando C,
Ponzio D,
Khoshbin A,
Stavrakis AI.
Trends and patient factors associated with technology-assisted total hip arthroplasty
in the United States from 2005 to 2014. Arthroplast Today 2020; 6 (01) 112-117.e1
MissingFormLabel
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for Healthcare Research and Quality, Rockville, MD. Accessed July 15, 2025 at: www.hcup-us.ahrq.gov/nrdoverview.jsp
MissingFormLabel
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van Walraven C,
Austin PC,
Jennings A,
Quan H,
Forster AJ.
A modification of the Elixhauser comorbidity measures into a point system for hospital
death using administrative data. Med Care 2009; 47 (06) 626-633
MissingFormLabel
- 21
Kotzur TM,
Singh A,
Peng LN,
Makhani AA,
Seifi A,
Moore CC.
Comparing common risk assessment tools to predict outcomes in total knee arthroplasty.
J Arthroplasty 2024; 39 (9S2): S163 , 170.e11
MissingFormLabel
- 22
Moskal JT,
Capps SG.
Acetabular component positioning in total hip arthroplasty: an evidence-based analysis.
J Arthroplasty 2011; 26 (08) 1432-1437
MissingFormLabel
- 23
Lewinnek GE,
Lewis JL,
Tarr R,
Compere CL,
Zimmerman JR.
Dislocations after total hip-replacement arthroplasties. J Bone Joint Surg Am 1978;
60 (02) 217-220
MissingFormLabel
- 24
Tauriainen TJT,
Niinimäki TT,
Niinimäki JL,
Nousiainen TOP,
Leppilahti JI.
Poor acetabular component orientation increases revision risk in metal-on-metal hip
arthroplasty. J Arthroplasty 2017; 32 (07) 2204-2207
MissingFormLabel
- 25
Sadhu A,
Nam D,
Coobs BR,
Barrack TN,
Nunley RM,
Barrack RL.
Acetabular component position and the risk of dislocation following primary and revision
total hip arthroplasty: A matched cohort analysis. J Arthroplasty 2017; 32 (03) 987-991
MissingFormLabel
- 26
Hernández A,
Lakhani K,
Núñez JH,
Mimendia I,
Pons A,
Barro V.
Can we trust combined anteversion and Lewinnek safe zone to avoid hip prosthesis dislocation?.
J Clin Orthop Trauma 2021; 21: 101562
MissingFormLabel
- 27
Piple AS,
Wang JC,
Hill W.
et al.
Postoperative outcomes and trends in computer-navigated and robotic-assisted total
hip arthroplasty. Hip Int 2024; 34 (05) 569-577
MissingFormLabel
- 28
Confalonieri N,
Manzotti A,
Montironi F,
Pullen C.
Leg length discrepancy, dislocation rate, and offset in total hip replacement using
a short modular stem: navigation vs conventional freehand. Orthopedics 2008 31. (10
Suppl 1): orthosupersite.com/view.asp?rID=35541
MissingFormLabel
- 29
Parratte S,
Ollivier M,
Lunebourg A,
Flecher X,
Argenson J-NA.
No benefit after THA performed with computer-assisted cup placement: 10-year results
of a randomized controlled study. Clin Orthop Relat Res 2016; 474 (10) 2085-2093
MissingFormLabel
- 30
Hamilton WG,
Sershon RA,
Gupta A.
et al.
Readmission rate and healthcare utilization outcomes of computer-assisted fluoroscopy-based
hip navigation versus manual total hip arthroplasty. Expert Rev Med Devices 2023;
20 (09) 779-789
MissingFormLabel
- 31
Korber S,
Antonios JK,
Sivasundaram L.
et al.
Utilization of technology-assisted total hip arthroplasty in the United States from
2005 to 2018. Arthroplast Today 2021; 12: 36-44
MissingFormLabel
- 32
Brown ML,
Reed JD,
Drinkwater CJ.
Imageless computer-assisted versus conventional total hip arthroplasty: one surgeon's
initial experience. J Arthroplasty 2014; 29 (05) 1015-1020
MissingFormLabel
- 33
de Palma L,
Procaccini R,
Soccetti A,
Marinelli M.
Hospital cost of treating early dislocation following hip arthroplasty. Hip Int 2012;
22 (01) 62-67
MissingFormLabel
- 34
Li Y-L,
Jia J,
Wu Q,
Ning G-Z,
Wu Q-L,
Feng S-Q.
Evidence-based computer-navigated total hip arthroplasty: an updated analysis of randomized
controlled trials. Eur J Orthop Surg Traumatol 2014; 24 (04) 531-538
MissingFormLabel
- 35
Aoude AA,
Aldebeyan SA,
Nooh A,
Weber MH,
Tanzer M.
Thirty-day complications of conventional and computer-assisted total knee and total
hip arthroplasty: Analysis of 103,855 patients in the American College of Surgeons
National Surgical Quality Improvement Program Database. J Arthroplasty 2016; 31 (08)
1674-1679
MissingFormLabel
- 36
Singh V,
Realyvasquez J,
Simcox T,
Rozell JC,
Schwarzkopf R,
Davidovitch RI.
Robotics versus navigation versus conventional total hip arthroplasty: does the use
of technology yield superior outcomes?. J Arthroplasty 2021; 36 (08) 2801-2807
MissingFormLabel
- 37
Urquhart DM,
Hanna FS,
Brennan SL.
et al.
Incidence and risk factors for deep surgical site infection after primary total hip
arthroplasty: a systematic review. J Arthroplasty 2010; 25 (08) 1216-22.e1 , 3
MissingFormLabel
- 38
Orland MD,
Lee RY,
Naami EE,
Patetta MJ,
Hussain AK,
Gonzalez MH.
Surgical duration implicated in major postoperative complications in total hip and
total knee arthroplasty: A retrospective cohort study. J Am Acad Orthop Surg Glob
Res Rev 2020; 4 (11) e20.00043
MissingFormLabel
- 39
Ross D,
Erkocak O,
Rasouli MR,
Parvizi J.
Operative time directly correlates with blood loss and need for blood transfusion
in total joint arthroplasty. Arch Bone Jt Surg 2019; 7 (03) 229-234
MissingFormLabel
- 40
Nathens AB,
Jurkovich GJ,
Maier RV.
et al.
Relationship between trauma center volume and outcomes. JAMA 2001; 285 (09) 1164-1171
MissingFormLabel
- 41
Hecht Ii CJ,
Porto JR,
Sanghvi PA,
Homma Y,
Sculco PK,
Kamath AF.
Navigating the learning curve: assessing caseload and comparing outcomes before and
after the learning curve of computer-navigated total hip arthroplasty. J Robot Surg
2024; 18 (01) 104
MissingFormLabel





