Author commentary on Zhenkai Luo et al.

Zhenkai Luo et al. A novel technique for submucosal tumors in the esophagus: mucosal zipper endoscopic resection

Removal of large or proximal esophageal submucosal tumors is currently challenging. In the novel technique of mucosal zipper endoscopic resection (MZER) a longitudinal mucosal incision is followed by submucosal dissection around the tumor. In this pilot study involving 24 patients, MZER had a 100 % success rate, with no cases of delayed bleeding or perforation. This promising procedure needs comprehensive prospective evaluation of its safety and efficacy.

 

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Publication History

Article published online:
24 September 2025