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Exp Clin Endocrinol Diabetes 2025; 133(01): 40-50
DOI: 10.1055/a-2414-5487
Mini-Review

Obstructive Sleep Apnoea and Type 1 Diabetes Mellitus: A Neglected Relationship?

Theodoros Panou
1   Deparment of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece (Ringgold ID: RIN112220)
2   Diabetes Centre-Diabetic Foot Clinic, Second Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece
,
Konstantinos Roukas
1   Deparment of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece (Ringgold ID: RIN112220)
,
Konstantina Chadia
1   Deparment of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece (Ringgold ID: RIN112220)
,
Evangelia Nena
3   Laboratory of Social Medicine, Democritus University of Thrace – Alexandropoulis Campus, Alexandroupolis, Greece (Ringgold ID: RIN112220)
,
Evanthia Gouveri
2   Diabetes Centre-Diabetic Foot Clinic, Second Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece
,
Nikolaos Papanas 
2   Diabetes Centre-Diabetic Foot Clinic, Second Department of Internal Medicine, Democritus University of Thrace, Alexandroupolis, Greece
,
Paschalis Steiropoulos
1   Deparment of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece (Ringgold ID: RIN112220)
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Abstract

Obstructive sleep apnoea (OSA) is regarded as a major health condition, progressively affecting an increased number of people around the world. The interplay between OSA and type 2 diabetes mellitus (T2DM) has been extensively studied. However, little is known about the relationship between OSA and type 1 diabetes mellitus (T1DM). This review provides insight into the prevalence of OSA in T1DM and its relationship with diabetic complications. Studies have hitherto yielded contradictory results on the occurrence of OSA in T1DM. Indeed, the risk of OSA in T1DM has ranged from 1 in 10 to more than 1 in 2 T1DM subjects. This high occurrence was confirmed by objective polysomnography as well as widely used subjective questionnaires. Multiple studies revealed the important correlation between OSA and diabetes complications. Both microvascular (nephropathy, neuropathy and retinopathy) and macrovascular complications appear to be associated with OSA occurrence, although some associations were not significant due to inadequate data. In conclusion, T1DM subjects carry a higher risk of undiagnosed OSA. Additional studies are needed to clarify the exact correlation between the two conditions.

Keywords

OSA - T1DM - diabetic complications


Publication History

Received: 25 June 2024

Accepted after revision: 12 September 2024

Accepted Manuscript online:
12 September 2024

Article published online:
25 October 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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