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DOI: 10.1055/a-2401-4901
Ein malignes Pilomatrixom im Bereich der Tonsille eines Hundes
A malignant pilomatrixoma in the tonsillar area of a dog
Zusammenfassung
Dieser Fall beschreibt einen 12 Jahre alten männlichen West Highland White Terrier, der aufgrund von Reverse Sneezing und einer oralen Dysphagie in der Tierklinik vorgestellt wurde. In der endoskopischen Untersuchung konnte eine Umfangsvermehrung der rechten Tonsille dargestellt werden. Histologisch wurde ein malignes Pilomatrixom diagnostiziert. Es erfolgte eine chirurgische Zytoreduktion und eine anschließende Bestrahlungstherapie. Der Hund war 154 Tage symptomfrei und bei gutem Allgemeinbefinden. Aufgrund von erneuten klinischen Anzeichen und dem Verdacht einer symptomatischen Metastasierungen in den mandibulären Lymphknoten wurde der Hund 261 Tage nach der Diagnosestellung euthanasiert. Dies ist der erste Fallbericht eines malignen Pilomatrixom der Tonsille mit zytoreduktiver Chirurgie und adjuvanter Strahlentherapie.
Abstract
This case report discusses a 12-year-old West Highland White Terrier presented to the veterinary clinic with reverse sneezing and oral dysphagia. The endoscopic examination of the upper respiratory tract revealed a mass in the area of the right tonsil. Histologic examination confirmed the diagnosis of a malignant pilomatrixoma. The dog underwent surgical cytoreduction, followed by radiation therapy. After the treatment, the dog was free of clinical signs for 154 days and in good general condition. Due to recurrence of signs and the suspicion of clinically overt metastases in the mandibular lymph nodes, the dog was euthanized 261 days after the diagnosis. This is the first report of a malignant pilomatrixoma in the tonsillar area that has been treated with cytoreductive surgery and radiation therapy.
Publication History
Received: 12 July 2023
Accepted: 17 April 2024
Article published online:
24 October 2024
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Germany
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Literatur
- 1 Kessler M. Kleintieronkologie: Diagnose und Therapie von Tumorerkrankungen bei Hund und Katze 4th ed. Stuttgart: Georg Thieme Verlag; 2022: 310-318
- 2 Zwicker GM, Eyster RC, Sells DM. et al. Spontaneous skin neoplasms in aged Sprague-Dawley rats. Toxicol Pathol 1992; 20: 327-340
- 3 Gedon J. Hauttumoren des Hundes. Kleintier konkret 2017; 20: 18-27
- 4 Scott DW, Anderson WI. Canine hair follicle neoplasms: a retrospective analysis of 80 cases. (1986-1987) Vet Dermatol 1991; 2: 143-150
- 5 Carroll EE, Fossey SL, Magnus LM. et al. Malignant pilomatricoma in 3 dogs. Vet Pathol 2010; 47: 937-943
- 6 Ham LV, Van Bree H, Maenhout T. et al. Metastatic pilomatrixoma presenting as paraplegia in a dog. J Small Anim Pract 1991; 32: 27-30
- 7 Jackson K, Boger L, Goldschmidt M. et al. Malignant pilomatricoma in a soft-coated Wheaten Terrier. Vet Clin Pathol 2010; 39: 236-240
- 8 Barrot AC, Carioto L, Gains M. et al. Metastatic malignant pilomatrixoma, acanthomatous ameloblastoma, and liver tumor in a dog with polyphagia, polyuria, polydipsia, and weight loss. Can Vet J 2013; 54: 387
- 9 Adams WM, Miller PE, Vail DM. et al. An accelerated technique for irradiation of malignant canine nasal and paranasal sinus tumors. Vet Radiol Ultrasound 1998; 39: 475-481
- 10 Vail D, Withrow S. Tumors of the skin and subcutaneous tissues. In: Withrow SJ, Macewen EG, eds. Small Animal Clinical Oncology 4th ed. 2007: 375-401
- 11 Goldschmidt MH, Thrall DE, Jeglum KA. et al. Malignant pilomatricoma in a dog. J Cutan Pathol 1981; 8: 375-381
- 12 Johnson RP, Johnson JA, Groom SC. et al. Malignant pilomatrixoma in an old English sheepdog. Can Vet J 1983; 24: 392
- 13 Rodriguez F, Herraez P, Rodriguez E. et al. Metastatic pilomatrixoma associated with neurological signs in a dog. Vet Rec 1995; 137: 247-248
- 14 Treggiari E, Elliott J. Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates. Open Vet J 2017; 7: 208-213
- 15 Da Silva EO, Green KT, Wasques DG. et al. Malignant pilomatricoma in a dog. J Comp Pathol 2012; 147: 214-217
- 16 Noiva RM, Costa FB, Pratas R. et al. Metastatic malignant pilomatricoma with bone and lung metastasis in a Portuguese Water Dog. Rev Port Cienc Vet 2012; 107: 101-104
- 17 Das D, Balachandran C, Pazhanivel N. et al. Pilomatricoma in a dog. Indian J Anim Res 2014; 48: 301-302
- 18 Forbis R, Helwig EB. Pilomatrixoma (calcifying epithelioma). Arch Dermatol 1961; 83: 606-618
- 19 Sells DM, Conroy JD. Malignant epithelial neoplasia with hair follicle differentiation in dogs: Malignant pilomatrixoma. J Comp Pathol 1976; 86: 121-129
- 20 Theilen GH, Madewell BR. Tumors of the skin and subcutaneous tissues. Vet Cancer Med 1979; 164
- 21 Lever WF. Histopathology of the skin. Philadelphia, London & Montreal: J. B. Lippincott Co; 1949
- 22 Nielson SW, Cole CR. Cutaneous epithelial neoplasms of the dog-a report of 153 cases. Am J Vet Res 1960; 21: 931-948
- 23 Martano M, Navas L, Meomartino L. et al. Malignant pilomatricoma with multiple bone metastases in a dog: Histological and immunohistochemical study. Exp Ther Med 2013; 5: 1005-1008
- 24 Lee EJ, Kim AY, Lee EM. et al. Malignant pilomatricoma in a young dog. Acta Vet 2016; 66: 556-561
- 25 Chung JY, Do SH, Park SJ. et al. Pilomatrixoma in a Maltese dog. Lab Anim Res 2010; 26: 117-120
- 26 Hoshino Y, Mori T, Sakai H. et al. Palliative radiation therapy in a dog with malignant trichoepithelioma. Aust Vet J 2012; 90: 210-213
- 27 Ruff CF, Lim CK, Ramos-Vara JA. et al. Imaging diagnosis-nuclear scintigraphic, radiological, and pathologic characteristics of metastatic pilomatricoma in a dog. Vet Radiol Ultrasound 2016; 57: E58-E62