Diabetes mellitus und Herz

Katharina Schütt; Thomas Forst; Andreas L. Birkenfeld; Andreas Zirlik; Dirk Müller-Wieland; Nikolaus Marx

doi:10.1055/a-2305-6236

Diabetes aktuell, Table of Contents

Diabetes aktuell 2024; 22(03): 98-102
DOI: 10.1055/a-2305-6236

Schwerpunkt

Diabetes mellitus und Herz

Notwendigkeit einer gezielten Risikostratifizierung und konsequenten Behandlung

Katharina Schütt

¹Medizinische Klinik I – Kardiologie, Angiologie und Internistische Intensivmedizin, Uniklinik RWTH Aachen, Aachen

,

Thomas Forst

²CRS Clinical Research Services Mannheim GmbH, Mannheim

,

Andreas L. Birkenfeld

³Medizinische Klinik IV, Universitätsklinikum Tübingen, Tübingen

⁴Institut für Diabetesforschung und Metabolische Erkrankungen (IDM) des Helmholtz Zentrums München an der Universität Tübingen, Deutsches Zentrum für Diabetesforschung (DZD e. V.)

,

Andreas Zirlik

⁵Klinik für Innere Medizin – Abteilung für Kardiologie, LKH Universitätsklinikum Graz, Medizinische Universität Graz (Österreich)

,

Dirk Müller-Wieland

¹Medizinische Klinik I – Kardiologie, Angiologie und Internistische Intensivmedizin, Uniklinik RWTH Aachen, Aachen

,

Nikolaus Marx

¹Medizinische Klinik I – Kardiologie, Angiologie und Internistische Intensivmedizin, Uniklinik RWTH Aachen, Aachen

› Author Affiliations

Abstract

Full Text

References

Literatur
1 Anker SD, Butler J, Filippatos G. et al Empagliflozin in Heart Failure with a Preserved Ejection Fraction. N Engl J Med 2021; 385: 1451-1461
2 Di Angelantonio E, Kaptoge S., Emerging Risk Factors C. et al Association of Cardiometabolic Multimorbidity With Mortality. JAMA 2015; 314: 52-60
3 Consentino FF, Grant PJ, Aboyans V. et al 2019 ESC guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD. Eur Heart J 2020; 41: 255-323
4 Zinman B, Wanner C, Lachin JM. et al Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med 2015: 373
5 Neal B, Perkovic V, Mahaffey KW. et al Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. N Engl J Med 2017; 377: 644-657
6 Wiviott SD, Raz I, Bonaca MP. et al Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med 2018; 380: 347-357
7 Marso SP, Daniels GH, Brown-Frandsen K. et al Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med 2016; 375: 311-322
8 Marso SP, Bain SC, Consoli A. et al Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. N Engl J Med 2016; 375: 1834-1844
9 Hernandez AF, Green JB, Janmohamed S. et al Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebocontrolled trial. Lancet 2018; 392: 1519-1529
10 Gerstein HC, Colhoun HM, Dagenais GR. et al Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial. Lancet 2019; 394: 121-130
11 Husain M, Birkenfeld AL, Donsmark M. et al Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. N Engl J Med 2019; 381: 841-851
12 Marso SP, Bain SC, Consoli A. et al Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. N Engl J Med 2016; 375: 1834-1844
13 Nichols GA, Gullion CM, Koro CE. et al The incidence of congestive heart failure in type 2 diabetes: an update. Diabetes Care 2004; 27: 1879-1884
14 MacDonald MR, Petrie MC, Varyani F. et al Impact of diabetes on outcomes in patients with low and preserved ejection fraction heart failure: an analysis of the Candesartan in Heart failure: Assessment of Reduction in Mortality and morbidity (CHARM) programme. Eur Heart J 2008; 29: 1377-1385
15 McDonagh TA, Metra M, Adamo M. et al 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 2021; 42: 3599-3726
16 McMurray JJV, Solomon SD, Inzucchi SE. et al Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction. N Engl J Med 2019; 381: 1995-2008
17 Packer M, Anker SD, Butler J. et al Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure. N Engl J Med 2020; 383: 1413-1424
18 Zannad F, Ferreira JP, Pocock SJ. et al SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials. Lancet 2020; 396: 819-829
19 Kirchhof P, Benussi S, Kotecha D. et al 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS: The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC)Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESCEndorsed by the European Stroke Organisation (ESO). Eur Heart J 2016; 37: 2893-2962
20 Solomon SD, McMurray JJV, Claggett BE. et al Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction. N Engl J Med 2022; 387: 1089-1098
21 Pitt B, Filippatos GD, Agarwal R. et al Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes. N Engl J Med 2021; 385: 2252-2263
22 Bakris GL, Agarwal R, Anker SD. et al Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes. N Engl J Med 2020; 383: 2219-2229
23 Agarwal R, Filippatos G, Pitt B. et al Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis. Eur Heart J 2022; 43: 474-484