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Ultraschall Med 2024; 45(03): 277-284
DOI: 10.1055/a-2048-8782
Original Article

Prevalence and distribution of ultrasound-detected hand synovial abnormalities in a middle-aged and older population

Prävalenz und Verteilung sonografisch nachgewiesener synovialer Anomalien der Hand in einer Bevölkerung mittleren und höheren Alters
Ting Jiang  ‡
1   Department of Orthopaedics, Xiangya Hospital, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
2   Department of Ultrasonography, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
3   Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN6123)
4   Pain Centre Versus Arthritis UK, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN6123)
,
Tuo Yang‡
3   Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN6123)
4   Pain Centre Versus Arthritis UK, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN6123)
5   Health Management Center, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
,
Weiya Zhang
3   Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN6123)
4   Pain Centre Versus Arthritis UK, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN6123)
,
Michael Doherty
3   Academic Rheumatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN6123)
4   Pain Centre Versus Arthritis UK, University of Nottingham, Nottingham, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN6123)
,
Yuqing Zhang
6   Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, United States (Ringgold ID: RIN1811)
7   The Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, United States (Ringgold ID: RIN1811)
,
Chao Zeng
8   Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
9   Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
10   National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
,
Aliya Sarmanova
11   Musculoskeletal Research Unit, Bristol Medical School, University of Bristol, Bristol, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN1980)
,
Zidan Yang
9   Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
,
Jiatian Li
8   Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
,
Yilun Wang
8   Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
9   Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
,
Yuqing Wang
8   Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
,
Abasiama D. Obotiba
12   Department of Health and Care Professions, Faculty of Health and Life Sciences, University of Exeter, Exeter, United Kingdom of Great Britain and Northern Ireland (Ringgold ID: RIN3286)
,
Guanghua Lei
8   Department of Orthopaedics, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
9   Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
10   National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
,
Jie Wei
5   Health Management Center, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
9   Hunan Key Laboratory of Joint Degeneration and Injury, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
10   National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University, Changsha, China (Ringgold ID: RIN159374)
13   Department of Epidemiology and Health Statistics, Central South University Xiangya School of Public Health, Changsha, China (Ringgold ID: RIN506614)
› Author AffiliationsSupported by: National Natural Science Foundation of China 81902264, 81902265, 81930071, 82072502, U21A20352
Supported by: Project Program of National Clinical Research Center for Geriatric Disorders (Xiangya Hospital) 2020LNJJ03
Supported by: Science and Technology Program of Hunan Province 2019RS2010
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Correction: Prevalence and distribution of ultrasound-detected hand synovial abnormalities in a middle-aged and older populationUltraschall Med 2024; 45(03): e1-e1
DOI: 10.1055/a-2195-7358

Abstract

Objective Synovial abnormalities are modifiable targets for hand pain and osteoarthritis. We examined the prevalence and distribution of ultrasound-detected hand synovial abnormalities in a community-derived sample of older people in China.

Methods Within the Xiangya Osteoarthritis Study, a community-based study, we assessed synovial hypertrophy (SH), joint effusion, and Power Doppler signal (PDS) on all fingers and thumbs of both hands using standardized ultrasound examinations (score: 0–3). We assessed distribution patterns of SH and effusion using χ2-test and interrelationships of SH and effusion in different joints and hands by generalized estimating equations.

Results Among 3,623 participants (mean age: 64.4 years; women: 58.1%), prevalence of SH, effusion and PDS were 85.5%, 87.3% and 1.5%, respectively. Prevalence of SH, effusion and PDS increased with age, was higher in the right hand than in the left hand and was more common in proximal than in distal hand joints. SH and effusion often occurred in multiple joints (P < 0.001). SH in one joint was strongly associated with presence of SH in the same joint of the opposite hand (odds ratio [OR]= 6.60, 95% confidence interval [CI]: 6.19–7.03) followed by SH in other joints in the same row, (OR=5.70, 95%CI: 5.32–6.11), and then other joints in the same ray of the same hand (OR=1.49, 95%CI: 1.39–1.60). Similar patterns were observed for effusion.

Conclusion Hand synovial abnormalities are common among older people, often affect multiple hand joints and present a unique pattern. These findings suggest both systemic and mechanical factors play roles in their occurrence.

Zusammenfassung

Ziel Synoviale Anomalien sind modifizierbare Ursachen für Handschmerzen und Osteoarthritis. Wir untersuchten die Prävalenz und die Verteilung der sonografisch nachgewiesenen synovialen Anomalien der Hand aus der Bevölkerung stammenden Stichprobe älterer Menschen in China.

Methoden In einer community-basierten Studie haben wir synoviale Hypertrophie (SH), Gelenkerguss und Power-Doppler-Signal (PDS) für alle Fingern und Daumen beider Hände mit standardisierten Ultraschalluntersuchungen (Score: 0–3) untersucht. Wir bewerteten die Verteilungsmuster von SH und Erguss mit dem χ2-Test und die Relationen von SH und Erguss in unterschiedlichen Gelenken und Händen mittels generalisierter Schätzgleichungen.

Ergebnisse Unter 3.623 Teilnehmern (Durchschnittsalter: 64,4 Jahre; Frauen: 58,1%) betrug die Prävalenz von SH 85,5 %, von Erguss 87,3 % und von PDS 1,5 %. Die Prävalenz von SH, Erguss und PDS nahm mit dem Alter zu, war in der rechten Hand höher als in der linken Hand und trat häufiger in proximalen als distalen Handgelenken auf. SH und Erguss traten häufig in mehreren Gelenken auf (p < 0,001). SH in einem Gelenk war stark assoziiert mit dem Vorhandensein von SH im gleichen Gelenk der anderen Hand (Odds Ratio [OR]= 6,60; 95% Konfidenzintervall [CI]: 6,19–7,03), gefolgt von SH in anderen Gelenken derselben Reihe (OR=5,70; 95% CI: 5,32–6,11) sowie in anderen Gelenken im selben Strahl derselben Hand (OR=1,49; 95% CI: 1,39–1,60). Ähnliche Muster wurden für Ergüsse beobachtet.

Schlussfolgerung Synoviale Anomalien der Hand sind bei älteren Menschen häufig, betreffen oft mehrere Handgelenke und weisen ein einzigartiges Muster auf. Diese Ergebnisse deuten darauf hin, dass sowohl systemische als auch mechanische Faktoren bei ihrem Auftreten eine Rolle spielen.

Keywords

Synovial abnormalities - Hand - Prevalence - Distribution - Ultrasonography

Supplementary Material



Publication History

Received: 29 June 2022

Accepted after revision: 07 March 2023

Accepted Manuscript online:
07 March 2023

Article published online:
03 May 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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