Trainingsinduzierte Hypoalgesie im Ausdauersport

Thomas Weiß; Hannu Luomajoki; Maria Geisler

doi:10.1055/a-2030-8988

MSK – Muskuloskelettale Physiotherapie, Table of Contents

MSK – Muskuloskelettale Physiotherapie 2023; 27(02): 92-99
DOI: 10.1055/a-2030-8988

Die Schmerzseiten

Trainingsinduzierte Hypoalgesie im Ausdauersport

Thomas Weiß

,

Hannu Luomajoki

,

Maria Geisler

Abstract

Menschen nehmen Schmerz sehr unterschiedlich wahr. Interessanterweise scheinen diejenigen, die Ausdauersport betreiben, über ein effizienteres Schmerzmodulationssystem zu verfügen als Nichtsportler*innen. Könnte Ausdauersport demnach einer Chronifizierung von Schmerzen entgegenwirken?

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References

Literatur
1 Treede RD, Rief W, Barke A. et al. Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11). Pain 2019; 160: 19-27
2 Kröner-Herwig B. Schmerz als biopsychosoziales Phänomen – eine Einführung. In: Kröner-Herwig B, Frettlöh J, Klinger R, Nilges P, Hrsg. Schmerzpsychotherapie: Grundlagen – Diagnostik – Krankheitsbilder – Behandlung. Berlin, Heidelberg: Springer; 2017.
3 Lang E, Eisele R, Jankowsky H. et al. Ergebnisqualität in der ambulanten Versorgung von Patienten mit chronischen Rückenschmerzen. Der Schmerz 2000; 14: 146-159
4 Tarnanen S, Luomajoki H. Trainingsinduzierte Hypoalgesie: Mit Bewegung gegen den Schmerz. SchmerzTherapie 2022; 5: 64-69
5 Tesarz J, Schuster AK, Hartmann M. et al. Pain perception in athletes compared to normally active controls: A systematic review with meta-analysis. Pain 2012; 153: 1253-1262
6 Flood A, Waddington G, Cathcart S. Examining the relationship between endogenous pain modulation capacity and endurance exercise performance. Res Sports Med 2017; 25: 300-312
7 Geisler M, Weiß T. Schmerzmodulation durch Ausdauersport. Manuelle Medizin 2022; 60: 143-150
8 Schaible H-G, Weiss T. Physiologie des Schmerzes und der Nozizeption. In: van den Berg F, Hrsg. Angewandte Physiologie: Band 4: Schmerzen verstehen und beeinflussen. 2. Aufl. Stuttgart: Georg Thieme Verlag; 2008
9 Tracey I, Mantyh PW. The cerebral signature for pain perception and its modulation. Neuron 2007; 55: 377-391
10 Basbaum AI, Fields HL. Endogenous pain control mechanisms: review and hypothesis. Ann Neurol 1978; 4: 451-462
11 Yilmaz P, Diers M, Diener S. et al. Brain correlates of stress-induced analgesia. Pain 2010; 151: 522-529
12 Koltyn KF. Analgesia following exercise: a review. Sports Med 2000; 29: 85-98
13 Amanzio M, Benedetti F. Neuropharmacological dissection of placebo analgesia: expectation-activated opioid systems versus conditioning-activated specific subsystems. J Neurosci 1999; 19: 484-494
14 Roa Romero Y, Straube T, Nitsch A. et al. Interaction between stimulus intensity and perceptual load in the attentional control of pain. Pain 2013; 154: 135-140
15 Yarnitsky D, Arendt-Nielsen L, Bouhassira D. et al. Recommendations on terminology and practice of psychophysical DNIC testing. Eur J Pain 2010; 14: 339
16 Damien J, Colloca L, Bellei-Rodriguez CE. et al. Pain Modulation: From Conditioned Pain Modulation to Placebo and Nocebo Effects in Experimental and Clinical Pain. Int Rev Neurobiol 2018; 139: 255-296
17 Yarnitsky D, Bouhassira D, Drewes AM. et al. Recommendations on practice of conditioned pain modulation (CPM) testing. Eur J Pain 2015; 19: 805-806
18 McPhee ME, Vaegter HB, Graven-Nielsen T. Alterations in pronociceptive and antinociceptive mechanisms in patients with low back pain: a systematic review with meta-analysis. Pain 2020; 161: 464-475
19 Lewis GN, Rice DA, McNair PJ. Conditioned Pain Modulation in Populations With Chronic Pain: A Systematic Review and Meta-Analysis. J Pain 2012; 13: 936-944
20 Bingel U. Mechanisms of endogenous pain modulation illustrated by placebo analgesia: functional imaging findings. Schmerz 2010; 24: 122-129
21 Wager TD, Atlas LY. The neuroscience of placebo effects: connecting context, learning and health. Nat Rev Neurosci 2015; 16: 403-418
22 Black J, Chesher GB, Starmer GA. et al. The painlessness of the long distance runner. Med J Aust 1979; 1: 522-523
23 Naugle KM, Fillingim RB, Riley JL. A meta-analytic review of the hypoalgesic effects of exercise. J Pain 2012; 13: 1139-1150
24 Koltyn KF. Exercise-Induced Hypoalgesia and Intensity of Exercise. Sports Med 2002; 32: 477-487
25 Hoffman MD, Hoffman DR. Does aerobic exercise improve pain perception and mood? A review of the evidence related to healthy and chronic pain subjects. Curr Pain Headache Rep 2007; 11: 93-97
26 Janal MN, Colt EW, Clark WC. et al. Pain sensitivity, mood and plasma endocrine levels in man following long-distance running: effects of naloxone. Pain 1984; 19: 13-25
27 Goldfarb AH, Jamurtas AZ. Beta-endorphin response to exercise. An update. Sports Med 1997; 24: 8-16
28 Dearman J, Francis KT. Plasma levels of catecholamines, cortisol, and beta-endorphins in male athletes after running 26.2, 6, and 2 miles. J Sports Med Phys Fitness 1983; 23: 30-38
29 Boecker H, Sprenger T, Spilker ME. et al. The runner's high: opioidergic mechanisms in the human brain. Cereb Cortex 2008; 18: 2523-2531
30 Scheef L, Jankowski J, Daamen M. et al. An fMRI study on the acute effects of exercise on pain processing in trained athletes. Pain 2012; 153: 1702-1714
31 Geisler M, Eichelkraut L, Miltner WHR. et al. Expectation of exercise in trained athletes results in a reduction of central processing to nociceptive stimulation. Behav Brain Res 2019; 356: 314-321
32 Geisler M, Eichelkraut L, Miltner WHR. et al. An fMRI study on runner’s high and exercise-induced hypoalgesia after a 2-h-run in trained non-elite male athletes. Sport Sci Health 2020; 16: 159-167
33 Fuss J, Gass P. Endocannabinoids and voluntary activity in mice: runner's high and long-term consequences in emotional behaviors. Exp Neurol 2010; 224: 103-105
34 Fuss J, Steinle J, Bindila L. et al. A runner’s high depends on cannabinoid receptors in mice. PNAS 2015; 112: 13105-13108
35 Geva N, Defrin R. Enhanced pain modulation among triathletes: a possible explanation for their exceptional capabilities. Pain 2013; 154: 2317-2323
36 Johnson MH, Stewart J, Humphries SA. et al. Marathon runnersʼ reaction to potassium iontophoretic experimental pain: pain tolerance, pain threshold, coping and self-efficacy. Eur J Pain 2012; 16: 767-774
37 Freund W, Weber F, Billich C. et al. Ultra-marathon runners are different: investigations into pain tolerance and personality traits of participants of the TransEurope FootRace 2009. Pain Pract 2013; 13: 524-532
38 Pettersen SD, Aslaksen PM, Pettersen SA. Pain Processing in Elite and High-Level Athletes Compared to Non-athletes. Front Psychol 2020; 11: 1908
39 Flood A, Waddington G, Thompson K. et al. Increased conditioned pain modulation in athletes. J Sports Sci 2017; 35: 1066-1072
40 Geisler M, Ritter A, Herbsleb M. et al. Neural mechanisms of pain processing differ between endurance athletes and nonathletes: A functional connectivity magnetic resonance imaging study. Hum Brain Mapp 2021;
41 Geisler M, Herbsleb M, Bär K-J. et al. Dissociation of Endogenous Pain Inhibition Due to Conditioned Pain Modulation and Placebo in Male Athletes Versus Nonathletes. Front Psychol 2020; 11: 553530
42 McDougall J, Jutzeler CR, Scott A. et al. Conditioned pain modulation in elite athletes: a systematic review and meta-analysis. Scand J Pain 2020; 20: 429-438
43 Wager TD, Rilling JK, Smith EE. et al. Placebo-induced changes in FMRI in the anticipation and experience of pain. Science 2004; 303: 1162-1167
44 Grahl A, Onat S, Buchel C. The periaqueductal gray and Bayesian integration in placebo analgesia. eLife 2018; 7: e32930
45 Stein N, Sprenger C, Scholz J. et al. White matter integrity of the descending pain modulatory system is associated with interindividual differences in placebo analgesia. Pain 2012; 153: 2210-2217
46 Eippert F, Bingel U, Schoell ED. et al. Activation of the opioidergic descending pain control system underlies placebo analgesia. Neuron 2009; 63: 533-543
47 Alfredson H, Pietilä T, Jonsson P. et al. Heavy-Load Eccentric Calf Muscle Training For e Treatment of Chronic Achilles Tendinosis. Am J Sports Med 1998; 26: 360-366
48 Silbernagel KG, Thomeé R, Eriksson BI. et al. Continued sports activity, using a pain-monitoring model, during rehabilitation in patients with Achilles tendinopathy: a randomized controlled study. Am J Sports Med 2007; 35: 897-906