Die repetitive transkranielle Magnetstimulation (rTMS) zur Behandlung der unipolaren Depression – Schritt für Schritt

Die repetitive transkranielle Magnetstimulation (rTMS) ist ein effektives nicht-invasives Hirnstimulationsverfahren zur Behandlung von Depressionen. Das Verfahren ist sicher in der Durchführung, nebenwirkungsarm und stellt bei korrekter Durchführung eine wertvolle Ergänzung zu bereits bestehenden pharmakologischen und psychotherapeutischen Therapiemöglichkeiten dar.

Publication History

Article published online:
08 May 2023

• Literaturverzeichnis

• 1 Lefaucheur JP, Aleman A, Baeken C. et al. Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS): An update (2014–2018) (vol 131, pg 474, 2020). Clin Neurophysiol 2020; 131: 1168-1169
• 2 Bundesärztekammer (BÄK), Kassenärztliche Bundesvereinigung (KBV), Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF). Nationale VersorgungsLeitlinie Unipolare Depression – Leitlinienreport, Version 3.0. 2022 [cited: YYYY-MM-DD]. DOI: 10.6101/AZQ/000494
• 3 Plewnia C, Pasqualetti P, Grosse S. et al. Treatment of major depression with bilateral theta burst stimulation: A randomized controlled pilot trial. J Affect Disorders 2014; 156: 219-223
• 4 Blumberger DM, Vila-Rodriguez F, Thorpe KE. Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial (vol 391, pg 1683, 2018). Lancet 2018; 391: E24-E24
• 5 Li CT, Chen MH, Juan CH. et al. Efficacy of prefrontal theta-burst stimulation in refractory depression: a randomized sham-controlled study. Brain 2014; 137: 2088-2098
• 6 Plewnia C, Brendel B, Schwippel T. et al. Treatment of major depressive disorder with bilateral theta burst stimulation: study protocol for a randomized, double-blind, placebo-controlled multicenter trial (TBS-D). Eur Arch Psy Clin N 2021; 271: 1231-1243
• 7 Chang J, Chu Y, Ren Y. et al. Maintenance treatment of transcranial magnetic stimulation (TMS) for treatment-resistant depression patients responding to acute TMS treatment. Int J Physiol Pathophysiol Pharmacol 2020; 12: 128-133
• 8 Phillips AL, Burr RL, Dunner DL. Repetitive Transcranial Magnetic Stimulation in the Treatment of Bipolar Depression: Experience From a Clinical Setting. J Psychiatr Pract 2020; 26: 37-45
• 9 Hoffman RE, Gueorguieva R, Hawkins KA. et al. Temporoparietal transcranial magnetic stimulation for auditory hallucinations: Safety, efficacy and moderators in a fifty patient sample. Biol Psychiat 2005; 58: 97-104
• 10 Poulet E, Brunelin J, Bediou B. et al. Slow transcranial magnetic stimulation can rapidly reduce resistant auditory hallucinations in schizophrenia. Biol Psychiat 2005; 57: 188-191
• 11 Edinoff AN, Hegefeld TL, Petersen M. et al. Transcranial Magnetic Stimulation for Post-traumatic Stress Disorder. Front Psychiatry 2022; 13
• 12 Wang WL, Wang SY, Hung HY. et al. Safety of transcranial magnetic stimulation in unipolar depression: A systematic review and meta-analysis of randomized-controlled trials. J Affect Disord 2022; 301: 400-425
• 13 Wassermann EM. Side effects of repetitive transcranial magnetic stimulation. Depress Anxiety 2000; 12: 124-129