Genetische Krebsprädisposition und Tumorprädispositionssyndrome im Kindesalter

Die rasanten Fortschritte der molekularen Onkologie und der zunehmende Einsatz genetischer Diagnostik in allen Teilbereichen der Pädiatrie haben tumorprädisponierende Erkrankungen in- und außerhalb der Kinderonkologie in den Fokus gerückt. Dieser Beitrag beschreibt sowohl im Allgemeinen als auch an konkreten Beispielen die Chancen und Herausforderungen durch das zunehmende Wissen um das Vorliegen einer genetischen Tumorprädisposition.

Schlüsselwörter

Tumorprädisposition - Beckwith-Wiedemann-Syndrom - Neurofibromatose Typ 1 - Neurofibromatose Typ 2 - Li-Fraumeni-Syndrom

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