Meningeal Metastasis Causing Chronic Subdural Hematoma in a Cancer Patient with Bilateral Papilledema and Suspected Cerebral Venous Thrombosis: A Case Report

Abstract

Meningeal metastasis has been reported as a very rare cause of chronic subdural hematoma (CSH). Here, we report a female patient who had undergone initial burr hole drainage of a CSH at an outside hospital. Postoperatively, the patient additionally suffered from visual impairment due to bilateral papilledema and the patient was eventually transferred to our neurosurgical department for additional treatment. A craniotomy was performed and due to intraoperative suspicious findings, histopathologic samples were obtained that revealed a metastasis of thus far undiagnosed triple negative breast cancer. Furthermore, the patient was suspected to have a partial cerebral venous thrombosis (CVT). Our case report addresses this extremely rare clinical constellation. We provide a detailed overview on our patient's clinical and radiologic course, and discuss the potential association of CSH with meningeal metastasis and bilateral papilledema.

Keywords

cerebral venous thrombosis - chronic subdural hematoma - magnetic resonance imaging - meningeal metastasis - papilledema

^* These authors contributed equally.

Publication History

Received: 14 January 2022

Accepted: 19 April 2022

Accepted Manuscript online:
22 April 2022

Article published online:
20 September 2022

• References

• 1 Feghali J, Yang W, Huang J. Updates in chronic subdural hematoma: epidemiology, etiology, pathogenesis, treatment, and outcome. World Neurosurg 2020; 141: 339-345
• 2 Laigle-Donadey F, Taillibert S, Mokhtari K, Hildebrand J, Delattre JY. Dural metastases. J Neurooncol 2005; 75 (01) 57-61
• 3 Abunimer AM, Abou-Al-Shaar H, White TG, Li JY, Chalif DJ. Metastatic subdural hematoma with dural metastasis secondary to poorly differentiated adenocarcinoma of unknown origin. World Neurosurg 2019; 125: 343-346
• 4 Agarwal B, Das P, Nasim M. Dural metastatic cancer from primary breast carcinoma. Int J Neurosci 2010; 120 (06) 442-446
• 5 Boukas A, Sunderland GJ, Ross N. Prostate dural metastasis presenting as chronic subdural hematoma. A case report and review of the literature. Surg Neurol Int 2015; 6: 30
• 6 Braun EM, Burger LJ, Schlang HA. Subdural hematoma from metastatic malignant disease. Cancer 1973; 32 (06) 1370-1373
• 7 Bucci MN, Farhat SM. Metastatic adenocarcinoma of the prostate as a cause of subdural hematoma. J Urol 1986; 135 (04) 803-804
• 8 Cheng CL, Greenberg J, Hoover LA. Prostatic adenocarcinoma metastatic to chronic subdural hematoma membranes. Case report. J Neurosurg 1988; 68 (04) 642-644
• 9 Cheng YK, Wang TC, Yang JT, Lee MH, Su CH. Dural metastasis from prostatic adenocarcinoma mimicking chronic subdural hematoma. J Clin Neurosci 2009; 16 (08) 1084-1086
• 10 Cross PA, Ortega LG, Thedore N, Wadleigh RG. A subdural hematoma from metastatic esophageal cancer. Acta Oncol 1995; 34 (04) 538-540
• 11 Ichinose T, Ueno M, Watanabe T, Murakami KI, Minato H, Hayashi Y. A rare case of chronic subdural hematoma coexisting with metastatic tumor. World Neurosurg 2020; 139: 196-199
• 12 Jang SY, Kim CH, Cheong JH, Kim JM. Concomitant subdural hemorrhage and intracerebral hemorrhage due to brain metastasis of the hepatocellular carcinoma. Brain Tumor Res Treat 2015; 3 (01) 48-51
• 13 Katsube T, Kikuchi T, Konnno S. et al. Subdural hematoma associated with dural metastasis of gastric carcinoma: report of two cases. Anticancer Res 2007; 27 (6C): 4339-4344
• 14 Kuan-Yin T, Dueng-Yuan H, Hsin-I M. Subdural hematoma associated with skull and dural metastasis of gastric carcinoma: a case report. Turk Neurosurg 2013; 23 (06) 796-799
• 15 Kunii N, Morita A, Yoshikawa G, Kirino T. Subdural hematoma associated with dural metastasis: case report. Neurol Med Chir (Tokyo) 2005; 45 (10) 519-522
• 16 Mirsadeghi SM, Habibi Z, Meybodi KT, Nejat F, Tabatabai SA. Malignant subdural effusion associated with disseminated adenocarcinoma: a case report. Cases J 2008; 1 (01) 328
• 17 O'Meara C, Mahasneh T, Wilson P, I'Ons B, Alkhawaja D. Dural prostate metastasis resembling a chronic subdural haematoma. J Surg Case Rep 2012; 2012 (05) 7
• 18 Rocque BG, Başkaya MK. Spontaneous acute subdural hematoma as an initial presentation of choriocarcinoma: a case report. J Med Case Reports 2008; 2: 211
• 19 Malloy KA, Chigbu DI. Ocular manifestations uncover chronic subdural hematoma secondary to abuse. Optometry 2010; 81 (02) 61-70
• 20 Kretz A, Preul C, Fricke HJ, Witte OW, Terborg C. Unilateral optic neuropathy following subdural hematoma: a case report. J Med Case Reports 2010; 4: 19
• 21 Hasegawa S, Manabe H, Shimizu T, Itoh C, Suzuki S. Chronic subdural hematoma presenting visual disturbance: a case report. No To Shinkei 2001; 53 (03) 283-286
• 22 Silvis SM, Hiltunen S, Lindgren E. et al. Cancer and risk of cerebral venous thrombosis: a case-control study. J Thromb Haemost 2018; 16 (01) 90-95