Geriatrie up2date 2022; 4(03): 189-209
DOI: 10.1055/a-1814-6033
Dermatologie, Augenheilkunde, HNO

Die senile Katarakt

Age-related Cataract
Irmingard Neuhann
,
Lukas Neuhann
,
Thomas Neuhann

Zusammenfassung

Die Vorstellung der alten Griechen war, dass eine trübe Flüssigkeit über das Auge herabrinne – daher die vom Verb καταρρηγνυναι = herabfließen hergeleitete Bezeichnung. Diese Auffassung zur Pathophysiologie der Katarakt hat sich heute grundlegend geändert.

Abstract

The purpose of this article is a condensed overview of contemporaneous „state of art and knowledge“ of age-related cataract. As an introduction, some aspects of terminology, epidemiology, lens anatomy and pathophysiology of age-related cataract, selected for clinical interest and relevance, are outlined. Clinical aspects include signs and symptoms: Objective criteria for cortical, nuclear and posterior subcapsular cataract are described, followed by typical symptoms such as decreased visual acuity, contrast sensitivity and foggy vision, altered colour perception, decreased mesopic and scotopic vision, glare, myopization and monocular diplopia. Diagnostic evaluation consists of a general ophthalmic examination, including history, refraction and vision testing, tonometry and morphologic examination of anterior and posterior segment, and is supplemented by special tests and examinations, such as interference vision (retinometer), keratometry including corneal topo-/tomography, biometry (ultrasound and optical), specular microscopy of the corneal endothelium and OCT of the central retina. Treatment is exclusively surgical: Evaluating the indication for surgery individually, weighing chances and risks, determining individual decisions such as anesthesia, surgical technical options, target refraction and intraocular lens options is discussed in detail. Finally, some perioperative considerations for medical treatment and infection prophylaxis are outlined. The last section deals with short- and long-term complications and their management – including early pressure rises, corneal edema, inflammatory response and endophthalmitis, and, in the longer term, secondary cataract, refractive problems, cystoid macular edema and retinal detachment.

Kernaussagen
  • Die Alterskatarakt ist keine Krankheit im eigentlichen Sinne – sie ist eine natürliche Alterungsfolge und betrifft jeden Menschen, wenn auch in einer weiten zeitlichen Bandbreite des Auftretens mit relevanten funktionellen Konsequenzen.

  • Ihre einzig sinnvolle Behandlung ist die operative Entfernung der getrübten Linse und der Ersatz durch eine Kunstlinse. Dies ist eine der häufigsten Operationen am Menschen, wenn nicht die häufigste.

  • Das Erfolgs-/Risikoprofil von Kataraktoperationen ist unter derzeitigen Bedingungen extrem günstig.

  • Die Möglichkeiten der funktionellen Rehabilitation sind heute sehr vielfältig – eine sehr differenzierte individuelle Beratung ist deshalb unerlässlich.



Publication History

Article published online:
29 July 2022

© 2022. Thieme. All rights reserved.

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  • Literatur

  • 1 Hashemi H, Pakzad R, Yekta A. et al. Global and regional prevalence of age-related cataract: a comprehensive systematic review and meta-analysis. Eye (Lond) 2020; 34: 1357-1370
  • 2 Nartey A. The Pathophysiology of Cataract and Major Interventions to Retarding Its Progression: A Mini Review. Adv Ophthalmol Vis Syst 2017; 6: 00178 DOI: 10.15406/aovs.2017.06.00178.
  • 3 Mellerio J. Yellowing of the human lens: Nuclear and cortical contributions. Vision Res 1987; 27: 1581-1587
  • 4 Wang Q, Jiang W, Lin T. et al. Meta-analysis of accuracy of intraocular lens power calculation formulas in short eyes. Clin Exp Ophthalmol 2018; 46: 356-363
  • 5 Chen H, Chen X, Wang H. et al. Intraocular Lens power calculation after laser refractive surgery: a meta-analysis. Sci Rep 2020; 10: 2645
  • 6 Wei L, Meng J, Qi J. et al. Comparisons of intraocular lens power calculation methods for eyes with previous myopic laser refractive surgery: Bayesian network meta-analysis. J Cataract Refract Surg 2021; 47: 1011-1018
  • 7 Li T, Stein JD, Nallasamy N. AI-powered effective lens position prediction improves the accuracy of existing lens formulas. medrxiv 2020; DOI: 10.1101/2020.10.29.20222539.
  • 8 Savini G, Taroni L, Hoffer KJ. Recent developments in intraocular lens power calculation methods-update 2020. Ann Transl Med 2020; 8: 1553
  • 9 Hahn U, Krummenauer F, Kölbl B. et al. Determination of valid benchmarks for outcome indicators in cataract surgery: a multicenter, prospective cohort trial. Ophthalmology 2011; 118: 2105-2112
  • 10 Klein BE, Howard KP, Lee KE. et al. The relationship of cataract and cataract extraction to age-related macular degeneration: the Beaver Dam Eye Study. Ophthalmology 2012; 119: 1628-1633
  • 11 Chew EY, Sperduto RD, Milton RC. et al. Risk of advanced age-related macular degeneration after cataract surgery in the Age-Related Eye Disease Study: AREDS report 25. Ophthalmology 2009; 116: 297-303
  • 12 Casparis H, Lindsley K, Kuo IC. et al. Surgery for cataracts in people with age-related macular degeneration. Cochrane Database Syst Rev 2017; (02) CD006757
  • 13 Neuhann IM, Neuhann TF, Rohrbach JM. Intraocular lens calcification after keratoplasty. Cornea 2013; 32: e6-e10
  • 14 Roberts HW, Day AC, OʼBrart DP. Femtosecond laser-assisted cataract surgery: A review. Eur J Ophthalmol 2020; 30: 417-429
  • 15 Schweitzer C, Brezin A, Cochener B. et al. FEMCAT Study Group. Femtosecond laser-assisted versus phacoemulsification cataract surgery (FEMCAT): a multicentre participant-masked randomised superiority and cost-effectiveness trial. Lancet 2020; 395(10219): 212-224
  • 16 Shimada H, Nakashizuka H. Cataract surgery by intraoperative surface irrigation with 0.25 % povidone-iodine. J Clin Med 2021; 10: 3611
  • 17 Endophthalmitis Study Group, European Society of Cataract & Refractive Surgeons. Prophylaxis of postoperative endophthalmitis following cataract surgery: results of the ESCRS multicenter study and identification of risk factors. J Cataract Refract Surg 2007; 33: 978-988
  • 18 Wielders LHP, Schouten JSAG, Winkens B. et al. ESCRS PREMED Study Group. Randomized controlled European multicenter trial on the prevention of cystoid macular edema after cataract surgery in diabetics: ESCRS PREMED Study Report 2. J Cataract Refract Surg 2018; 44: 836-847
  • 19 Wielders LHP, Schouten JSAG, Winkens B. et al. ESCRS PREMED Study Group. European multicenter trial of the prevention of cystoid macular edema after cataract surgery in nondiabetics: ESCRS PREMED study report 1. J Cataract Refract Surg 2018; 44: 429-439
  • 20 Neuhann IM, Neuhann TF, Heimann H. et al. Retinal detachment after phacoemulsification in high myopia: analysis of 2356 cases. J Cataract Refract Surg 2008; 34: 1644-1657
  • 21 Bjerrum SS, Mikkelsen KL, La Cour M. Risk of pseudophakic retinal detachment in 202,226 patients using the fellow nonoperated eye as reference. Ophthalmology 2013; 120: 2573-2579