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Int J Sports Med 2022; 43(06): 505-511
DOI: 10.1055/a-1670-7707
DOI: 10.1055/a-1670-7707
Physiology & Biochemistry
Exercise Training Increases Serum Cardiac Troponin T Independent of Left Ventricular Mass
Funding This research was funded by Macao Polytechnic Institute (RP/ ESCSD-04/2020).
Abstract
The purpose of this study was to determine whether exercise training mediated cardiac troponin T (cTnT) and whether this was associated with increases in left ventricular mass (LVM). Fifty-four sedentary obese women were randomised to high-intensity interval training (HIIT, repeated 4–min cycling at 90% V̇O2max interspersed with 3–min rest), work-equivalent continuous aerobic training (CAT, continuous cycling at 60% V̇O2max) or a control group (CON). Resting serum cTnT was assessed using a high-sensitivity assay before and after 12 weeks of training. LVM was determined from 2D echocardiography at the same timepoints. Both HIIT and CAT induced a similar elevation (median 3.07 to 3.76 ng.l−1, p<0.05) in resting cTnT compared with pre-training and the CON (3.49 to 3.45 ng.l−1, p>0.05). LVM index in HIIT increased (62.2±7.8 to 73.1±14.1 g.m−2, p<0.05), but not in CAT (66.1±9.7 to 67.6±9.6 g.m−2, p>0.05) and CON (67.9±9.5 to 70.2±9.1 g.m−2, p>0.05). Training-induced changes in resting cTnT did not correlate with changes in LVM index (r=−0.025, p=0.857). These findings suggest that twelve weeks of either HIIT or CAT increased resting cTnT, but the effects were independent of any changes in LVM in sedentary obese women.
Key words
cardiac biomarker - high-intensity interval training - aerobic training - cardiovascular risk factorPublication History
Received: 11 June 2021
Accepted: 30 September 2021
Article published online:
06 December 2021
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