CC BY-NC-ND 4.0 · Endosc Int Open 2021; 09(08): E1243-E1245
DOI: 10.1055/a-1483-9776
VidEIO

Traction-assisted endoscopic full-thickness resection for extraluminal type gastrointestinal stromal tumor

Hiromu Fukuda
Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan
,
Noriya Uedo
Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan
,
Satoki Shichijo
Department of Gastrointestinal Oncology, Osaka International Cancer Institute, Osaka, Japan
› Author Affiliations
 

Endoscopic full-thickness resection (EFTR) was developed to treat upper gastrointestinal submucosal tumors (SMT) originating from the muscularis propria (MP) [1] [2]. However, EFTR for extra-luminal type SMT is difficult because this requires intraperitoneal manipulation. A clip-and-line traction method is useful for reduction of procedure time during endoscopic submucosal dissection of early gastric cancer [3] and EFTR of gastric SMT [4]. Recently, we have found that clip-and-line traction method is also useful for EFTR of extra-luminal type gastrointestinal stromal tumors (GISTs).

A woman in her 70 s underwent a chest computed tomography scan for anterior chest pain, which identified an exophytic tumor in the stomach. Esophagogastroduodenoscopy revealed an SMT in the gastric body ([Fig. 1]). Echoendoscopy revealed the 24-mm tumor connected to the muscularis propria and protruding into the peritoneal cavity ([Fig. 2]). EFTR was performed under general anesthesia with a double-channel multi-bending scope (GIF-2TQ260M; Olympus Medical Co., Ltd., Tokyo, Japan) using an IT knife 2 (KD-611L; Olympus) and a Flush Knife BT-S 2.0 (DK2620J-B20S; Fujifilm Medical, Co., Ltd., Tokyo, Japan) as follows ([Video 1]): 1) mucosal incision and submucosal dissection to expose the border between the tumor and the MP circumferentially around the tumor; 2) muscularis incision along the tumor margin ([Fig. 3a]); 3) A clip was tied with 3–0 polyester suture to the mucosa overlying the tumor ([Fig. 3b]); 4) The tumor was pulled into the gastric lumen, facilitating peritoneal dissection and a remnant MP incision without pseudo-capsule injury ([Fig. 3c]); and 5) purse-string closure of the gastric wall defect using multiple clips (SureClip ROCC-D-26-165-C; Micro-Tech, Nanjing, China) and endoloops (HX-400U-30; Olympus) was performed ([Fig. 3d]) [5]. The procedure took 110 min. Histological examination showed that the lesion was an intermediate-risk GIST. The patient began a liquid diet 4 days after the procedure and was discharged on day 8.

Zoom Image
Fig. 1 Esophagogastroduodenoscopy showing a submucosal tumor at the lesser curvature of the mid-gastric body.
Zoom Image
Fig. 2 Echoendoscopic image showing the exophytic low-echoic tumor measuring 24 mm, connected to the muscularis propria.

Video 1 Only a small amount of solution is injected into the submucosa because use of too much fluid makes recognition of tumor extent in the mucosa difficult. The mucosal incision is made about no more than 5 mm above the base of the tumor to create a mucosal defect of adequate size. During deep mucosal incision (trimming), muscularis incision, and serosal dissection, recognition of the tumor surface is important to avoid pseudo-capsule injury. The clip-and-line traction method facilitates identify the border between the tumor and surrounding tissue, thus enabling preservation of the pseudo-capsule. Circumferential exposure of the muscularis attachment makes completion of the muscularis incision easy. An endo-loop and four to six clips are applied to the mucosa around the gastric wall defect for purse-string closure, which is repeated until the closure is complete.


Quality:
Zoom Image
Fig. 3 a Muscularis incision along the margin of the tumor using the IT knife 2. b Applying a clip with a suture to the mucosa overlying the lesion. c Providing traction using the clip-and-line facilitates identification and dissection of the peritoneal plane underneath the tumor. d Completing the closure as a purse-string using multiple clips and endoloops.

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Competing interests

The authors declare that they have no conflict of interest.


Corresponding author

Noriya Uedo
Department of Gastrointestinal Oncology
Osaka International Cancer Institute
3-1-69 Otemae, Chuo-ku
Osaka 541-8567
Japan   
Fax: +81-6-6945-1900   

Publication History

Publication Date:
16 July 2021 (online)

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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Zoom Image
Fig. 1 Esophagogastroduodenoscopy showing a submucosal tumor at the lesser curvature of the mid-gastric body.
Zoom Image
Fig. 2 Echoendoscopic image showing the exophytic low-echoic tumor measuring 24 mm, connected to the muscularis propria.
Zoom Image
Fig. 3 a Muscularis incision along the margin of the tumor using the IT knife 2. b Applying a clip with a suture to the mucosa overlying the lesion. c Providing traction using the clip-and-line facilitates identification and dissection of the peritoneal plane underneath the tumor. d Completing the closure as a purse-string using multiple clips and endoloops.