A 58-year-old woman with history of coronary artery disease presented with hematochezia
and melena. In addition to aspirin and atorvastatin she was taking ibuprofen for headaches.
On presentation she was in hypovolemic shock. Her laboratory data was remarkable for
a hemoglobin concentration of 5 g/dL and mild leukocytosis (13 000/µL). The remaining
laboratory data was normal. After initial fluid resuscitation with intravenous saline
and after receiving transfusion with 2 units of units of packed red blood cells, the
patient underwent endoscopy. A large, deep prepyloric ulcer with a visible vessel
compressing the pyloric channel was seen ([Fig. 1]; [Video 1]). An over-the-scope clip (OTSC 11/6/t; Ovesco, Tübingen, Germany) was deployed.
However, the OTSC only grasped part of the fibrotic ulcer. Therefore, a decision was
made to place a second OTSC (12/6t). Because the ulcer was partly closing the duodenal
entrance, a 0.035-inch biliary guidewire was advanced into the duodenum to (a) maintain
visibility of the gastric outlet and (b) prevent closure of the duodenal bulb while
the second OTSC was being applied ([Video 1]). Application of the second OTSC was uneventful. Final inspection of the site revealed
adequately placed clips and a patent duodenum. The patient had an uneventful recovery,
her food intake was well tolerated, and she was discharged home in stable condition
48 hours later.
Fig. 1 A large and deep prepyloric ulcer with tightly adherent clot was present. The ulcer
was compressing the pyloric channel.
Video 1Final view of the deep prepyloric ulcer site after placement of second OTSC (12/6t).
This case stands out for several reasons. First, we have shown that placing two OTSCs
to close a large ulcer is feasible. Second, we present a safety technique using a
biliary wire advanced into the duodenum. By having a guide to visualize the duodenum,
wrongful closure of the lumen can be avoided. And, lastly, this case confirms the
utility of OTSCs for complex bleeding ulcers. The OTSC has strong apposing forces
and multiple studies have shown its efficacy to treat large ulcers and defects [1]
[2]
[3].
Endoscopy_UCTN_Code_CCL_1AB_2AC_3AZ
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