Medikamentöse Therapie der Herzinsuffizienz mit reduzierter Pumpfunktion

Seit Veröffentlichung der Leitlinien im Jahr 2016 lieferte eine Vielzahl von klinischen Studien neue Evidenz zur Therapieoptimierung der Herzinsuffizienz mit reduzierter Pumpfunktion (HFrEF). Gleichzeitig gestaltet sich aufgrund der Behandlungsvielfalt sowie häufiger Begleiterkrankungen die ohnehin komplexe HFrEF-Therapie schwieriger denn je. Dieser Artikel bietet ein Update zur aktuellen medikamentösen Therapie bei der HFrEF.

Abstract

Since publication of the European Society guidelines for the diagnosis and treatment of acute and chronic heart failure in 2016, numerous studies provided new evidence how to further optimize heart failure therapy.

Besides recent device-based therapeutic options, promising new drug developments give a glimmer of hope that the prognosis of this progressive heart disease could be somehow more controlled in the near future. At the same time, the variety of therapeutic options as well as the number of concomitant comorbidities makes the complex therapy of chronic heart failure more difficult than ever. This review aims to provide an update and practical support on the recent pharmacotherapeutic options in chronic heart failure.

Schlüsselwörter

Herzinsuffizienz - Pharmakotherapie - Prognose

Key words

heart failure - guidelines - medical therapy - device-based therapy

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