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CC BY-NC-ND 4.0 · International Journal of Epilepsy 2017; 04(01): 108-109
DOI: 10.1016/S2213-6320(17)30032-5
Multiple Choice Question
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Multiple Choice Question – Pharmacotherapy of Epilepsy

Dergalust Sunita
1   Adjunct Clinical Faculty at USC School of Pharmacy, Clinical Pharmacist in Neurology and Neurosurgery, Residency Program Director: PGY2 Neurology Specialty Pharmacy Program, West LA VA Medical Center, VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd (119), Los Angeles, CA 90073
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Publication History

Publication Date:
06 May 2018 (online)

 
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  • Q.1 Which of the following Anti-Epileptic Drugs (AEDs) should be avoided in an ICU patient who is on meropenem for pneumonia?

    • A) Sodium Valproate

    • B) Levetiracetam

    • C) Lacosamide

    • D) Midazolam

  • Q.2 All of the following AEDs except one are consider to be enzyme-inducing AEDs

    • A) Phenytoin

    • B) Carbamazepine

    • C) Primidone

    • D) Sodium Valproate

  • Q.3 The proposed mechanism of action for Levetiracetam is:

    • A) Modifies synaptic release of glutamate and GABA through action on vesicular function

    • B) Enhances slow inactivation of voltage-gated Sodium Channels

    • C) Inhibits Carbonic Anhydrase

    • D) Irreversibly inhibits GABA aminotransferase

  • Q.4 Rufinamide is indicated for

    • A) Adjunctive treatment of focal epilepsy

    • B) Adjunctive treatment of the Lennox-Gastaut Syndrome

    • C) Generalized tonic-clonic seizures

    • D) Status Epilepticus

  • Q.5 Which of the following side-effects can be attributed to Topiramate?

    • A) Nephrolithiasis

    • B) Gingival hyperplasia

    • C) Hemorrhagic Pancreatitis

    • D) Weight gain

  • Q.6 Fatal cases of aplastic anemia have been reported with use of the following AEDs:

    • A) Levetiracetam and Pregablin

    • B) Carbamazepine and Felbamate

    • C) Lacosamide and tiagabine

    • D) Phenytoin and phenobarbital

  • Q.7 Ethosuximide is indicated for treatment of:

    • A) Focal epilepsy

    • B) Generalized tonic-clonic seizures

    • C) Generalized non-motor (absence) seizures

    • D) Unclassified epilepsy

  • Q.8 Idiosyncratic reactions of Valproate include all of the following except

    • A) Hepatotoxicity

    • B) Pancreatitis

    • C) Thrombocytopenia

    • D) Psychosis

  • Q.9 Chronic dose-related adverse effects of valproate include all of the following except

    • A) Weight gain

    • B) Hair loss

    • C) Peripheral neuropathy

    • D) Endocrine and metabolic changes

  • Q.10 Vigabitrin is indicated for myoclonic epilepsy

    • A) True

    • B) False

Answer Keys-

  1. A

  2. D

  3. A

  4. B

  5. A

  6. B

  7. C

  8. D

  9. C

  10. B


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No conflict of interest has been declared by the author(s).

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