30. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber

Abken, H

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Abshagen, K

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Adams, DH

Virus Infection Of Hepatic Sinusoidal Endothelial Cells Regulates Hepatic T Cell Recruitment And Activation

Aggarwal, N

Alpha-1-Antitrypsin inhibits acute liver failure in mice

Ahlenstiel, G

Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection

Ahmad, S

Role of the Hypoxia Inducible Factors HIF-1α and HIF-2α during hepatic repair in a rat model of thioacetamide (TAA)-induced chronic liver damage

Differential localization of transferrin receptors and lipocalin-2 in rat hepatic and extra-hepatic organs during acute phase response

Changes of gene expression of different BMP-proteins in liver in different mouse and rat models of acute phase reaction

Aichler, M

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Aleithe, S

Wnt-signaling gradients and their impact on liver parenchymal heterogeneity – a link to xenobiotic metabolism

Crosstalk Morphogener Signalwege im Hepatozellulären Karzinom?

Der Wnt und Hedgehog Signalweg im Leberparenchym – Ein Einblick in Zonierung und Funktion

Allweiss, L

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Proliferation of hepatitis B virus infected human hepatocytes in humanized mice treated with the entry inhibitor Myrcludex-B induces strong cccDNA reduction and maintenance of cccDNA-free hepatocytes

Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay

Al Masaoudi, M

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Die CREMα-abhängige T-Zellantwort hemmt Progression der chronischen Lebererkrankung und deren Komplikationen

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Alonso, EA

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Alsamman, M

Hepatic stellate cell specific endoglin deletion modulates TGF-β signaling and aggravates liver fibrosis in two experimental models of murine liver injury

Optimization purity of isolated primary liver endothelial cells (LSEC) using adenoviral gene transfer

Alt, Y

Bedeutung des Caspase 8-Homologs cFLIP bei der metabolischen Leberschädigung

Alter, G

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Althausen, E

IL-8 hemmt die Suszeptibilität von CD56hochCD16negativ NK-Zellen gegenüber primären humanen hepatischen Sternzellen (HSC)

Alvarez, L

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Alwahsh, SM

Effect of direct single-dose irradiation on fat metabolism in rat liver: FAT/CD36 as the main responsible protein?

Alwan, AW

IL-8 hemmt die Suszeptibilität von CD56hochCD16negativ NK-Zellen gegenüber primären humanen hepatischen Sternzellen (HSC)

Amann, T

Keratinocyte growth factor inhibits hepatic inflammation and fibrosis in murine models of hepatic injury

Amanzada, A

Role of the Hypoxia Inducible Factors HIF-1α and HIF-2α during hepatic repair in a rat model of thioacetamide (TAA)-induced chronic liver damage

Changes of gene expression of different BMP-proteins in liver in different mouse and rat models of acute phase reaction

Andersen, JB

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Appenrodt, B

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Relevanz alter und neuer laborchemischer Parameter bei hospitalisierten Patienten mit Leberzirrhose und bakterieller Infektion

Arastéh, K

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Arck, P

Maternal Liver Damage Programs Offspring Allergic Inflammation in Mice

Armeanu-Ebinger, S

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Arnold, K

The lipogenic transcription factors Pparα and Pparγ as possible linkage between lipid metabolism and Hedgehog-Signalling Pathway?

Arreguin Camacho, LO

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Arslanow, A

Frequent PNPLA3 variant determines the fate of patients with chronic liver diseases: a Liver unit experience

Arzberger, S

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Baba, H

Long-term maintenance of human liver tissue by ex-vivo perfusion of liver sections

Bach, C

Correlation of fulminant hepatitis B and escape mutations in the 2nd loop of the HBsAg a-determinant

Baek, S

Avidity and shear stress-linked anchoring to tumor endothelium: transfer the principles of leukocyte adhesion for tumor-specific drug delivery

Bangen, JM

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Bantel, H

NAFLD staging by an improved ELISA for serum cytokeratin-18 fragments

Barikbin, R

An additional heme oxygenase-1 knockout increases systemic inflammation and fibrosis in MDR2 knockout mice

Identification of HO-1/CO-induced tumor protective genes in HCC

Barreiros, AP

Verlaufskontrolle des Fibrosegrades nach Lebertransplantation – Histologie und Transiente Elastografie mittels FibroScan im direkten Vergleich

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Battegay, M

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Bauer, T

Correlation of fulminant hepatitis B and escape mutations in the 2nd loop of the HBsAg a-determinant

HIV-1 infection impairs frequency and functionality of HBV-specific CD4 T cells in patients with chronic hepatitis B

Bechstein, WO

Multifocal β-catenin activated hepatocellular adenomas (HCA) with malignant transformation in hepatocellular carcinoma (HCC) after abuse of anabolic steroids

Gibt es prädiktive Parameter für das frühe HCC-Rezidiv nach Lebertransplantation?

Beck, M

Nup155 is linked to the p53 pathway in HCC

Becker, JS

Potential novel diagnostic applications of laser ablation inductively coupled plasma mass spectrometry in trace metal imaging of hepatic metal disorders

Becker, PP

MicroRNAs as Mediators in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Steatohepatitis

Bednarsch, J

Einfluss Oxaliplatin-haltiger Chemotherapie auf die Leberfunktion – Ein Fallbericht

Behm, B

Additive anti-Tumor Response to the Rabbit VX2 Hepatoma by Combined Radio Frequency Ablation and Toll like Receptor 9 Stimulation

Behrendt, P

The impact of adipokines hormones on HCV life-cycle

Behrens, G

Decline in Hepatitis E Virus (HEV) Antibody Prevalence in Southeastern Germany, 1996 – 2011

Bekeredjian-Ding, I

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Belhamer, H

Capsaicin impairs carcinogenesis of human intra- and extrahepatic cholangiocarcinoma cells

Bengsch, B

A protective HLA-B*27 restricted epitope contributes to viral control in chronic HCV infection despite presence of viral escape mutations and is characterized by a unique T cell phenotype

Benz, F

Erhöhte miR-122 Serumkonzentration stellen einen Biomarker für einen Leberschaden bei kritisch kranken Patienten dar

Berchtold, S

Secondary resistances to measles virus (MeV)-based virotherapy

Different 5-FC prodrug application regimes result in different oncolytic efficiencies

Berg, CP

Wirksamkeit und Sicherheit der Triple-Therapie mit Telaprevir bei 102 Patienten mit Hepatitis C, Genotyp 1: SVR 12 Daten

Aktivierung von T-Helferzellen durch Sulfitoxidase (SO), einem Autoantigen bei der primär-sklerosierenden Cholangitis (PSC)

Epidemiologische Entwicklung und Genotypisierung von Patienten mit einer chronischer Hepatitis B in Deutschland: Hinweise für einen Rückgang des Genotyp A zu Gunsten des Genotyp D

Verträglichkeit und Wirksamkeit einer Telaprevir Triple-Therapie der Hepatitis C, Genotyp 1 nach Lebertransplantation – SVR 24 Daten

Nachweis von funktionellen Autoantikörpern gegen den muskarinischen Acetylcholinrezeptor M3 (M3AchR) in Seren von Patienten mit autoimmunen Lebererkrankungen

Berg, T

Endogenous oxidized LDL levels predict treatment response in interferon-based therapy of chronic hepatitis C

Berger, A

Secondary resistances to measles virus (MeV)-based virotherapy

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Berger, C

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Bergheim, I

Einfluss von Citrullin auf die Entstehung einer Western Style Diät-induzierten nicht alkoholbedingten Fettlebererkrankung (NAFLD): Untersuchungen im Mausmodell

Berr, F

MicroRNAs as Mediators in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Steatohepatitis

Bertoletti, A

Dominance of cytolytic effector functions in hepatitis B virus-specific CD8+ T cell and NK cell mediated antiviral efficacy using hepatitis B virus infected hepatocytes overexpressing human sodium taurocholate cotransporting polypeptide

Bettinger, D

Efficacy and safety of transjugular intrahepatic portosystemic shunt in patients with hepatocellular carcinoma: a single center experience

Single measurement of hemoglobin predicts outcome of HCC patients

Bhagani, S

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Bidmon, HJ

Hepatische Enzephalopathie und Osmolyttransporter Expression in kultivierten Rattenastrozyten und im Rattenhirn

Bielefeld, T

Differentialdiagnose des hiliären Cholangiocarcinoms (Klatskin-Tumor): Extrapankreatische Form einer IgG4-positiven Autoimmunpankreatitis – Ein Fallbericht

Langzeitüberleben mit TIPS

Korrelation der nicht-invasiven ShearWave-Elastografie und der sonographisch assistierten Leberbiopsie bei der Bestimmung des Leberfibrosgrades

Bielefeldt, T

Nebenwirkungsspektrum während und nach erfolgreicher HCV Triple-Therapie nach Leberlebendtransplantation

Sonographische Darstellung des Ductus thoracicus bei Leberzirrhose: Ein neues diagnostisches Tool?

Bissinger, AL

Epidemiologische Entwicklung und Genotypisierung von Patienten mit einer chronischer Hepatitis B in Deutschland: Hinweise für einen Rückgang des Genotyp A zu Gunsten des Genotyp D

Bissinger, M

Role of A20(TNFAIP3) in mediating TNFα-induced pathways activation in mouse hepatoma cell lines and primary hepatocytes

Bitzer, M

Secondary resistances to measles virus (MeV)-based virotherapy

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Bitzer, MP

Different 5-FC prodrug application regimes result in different oncolytic efficiencies

Blanke, A

Induktion einer hepatischen Insulinresistenz durch PGE1, PGE2 und PGE3 in primären Ratten-Hepatozyten

Blatkiewicz, M

Individuals with the PNPLA3 (adiponutrin) variant present with unexpected body fat composition: a study in one thousand healthy blood donors

Blum, HE

Restoration of Hepatitis C virus-specific CD8+ T-cell responses in patients undergoing IFN-free antiviral therapy

Dominance of cytolytic effector functions in hepatitis B virus-specific CD8+ T cell and NK cell mediated antiviral efficacy using hepatitis B virus infected hepatocytes overexpressing human sodium taurocholate cotransporting polypeptide

Boaru, SG

TGF-β1 modulates LPS-induced NLRP3 inflammasome activity

Blockade of NLRP3 expression in primary hepatocytes by inhibitors of NF-κB signalling

Böcher, WO

Restoration of Hepatitis C virus-specific CD8+ T-cell responses in patients undergoing IFN-free antiviral therapy

Bode, JG

The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection

Intercellular communication of macrophages and hepatocytes and its impact on macrophage differentiation and activation

Hepatitis C virus induced suppression of IκBζ and interference with IκBζ induced Lipocalin2 Expression

Hepatitis C virus infection results in a reorganization of the expression pattern of ErbB receptor family members on its host cell

Hepatitis C Virus modulates TNFα-induced chemokine production and enables EGF to induce chemokine production in its host cell

Boekschoten, MV

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Boerner, T

Tumor containment by immune cells and fibrotic capsule improve survival of patients following resection of colorectal liver metastasis

Boesecke, C

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Boettger, J

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Bohle, RM

Intrahepatic cholestasis-associated ATP8B1 variation underlying protracted cholestatic course of acute hepatitis E virus infection

Bohne, F

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Bohrer, AM

Decades after spontaneous HBsAg clearance the CD8+ T cell immune response is less vigorous compared to chronic hepatitis B viral infection

Bojunga, J

Severe 25-hydroxyvitamin D deficiency identifies HCC patients with a poor prognosis

Borkham-Kamphorst, E

Impact of soluble Endoglin on TGF-β1 mediated immediate early responses in HepG2 cells

Antifibrotic effects of CCN1/CYR61 in primary portal myofibroblasts through induction of reactive oxygen species and resulting apoptosis

Blockade of NLRP3 expression in primary hepatocytes by inhibitors of NF-κB signalling

Bosserhoff, A

Expression and function of methylthioadenosine phosphorylase (MTAP) in activated hepatic stellate

Keratinocyte growth factor inhibits hepatic inflammation and fibrosis in murine models of hepatic injury

Hepatic steatosis enhances growth and invasiveness of hepatocellular carcinoma

Glucose transporter isoform 1 (GLUT1) expression determines tumorigenicity of melanoma cells and their potential to form hepatic metastasis

Expression and function of glucose transporter 1 (GLUT1) expression in activated hepatic stellate cells

Böttger, J

Wnt-signaling gradients and their impact on liver parenchymal heterogeneity – a link to xenobiotic metabolism

Böttinger, N

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Bovensiepen, C

Leberinfitrierende CD4 T Zellen bei der autoimmunen Hepatitis zeigen ein distinktes TH1 Profil

Bowe, A

Fxr-independent expression of the oncofetal marker Neighbor of Punc E11 after bile duct ligation in the adult mouse liver

Expression pattern of the stem/progenitor cell marker Neighbor of Punc E 11 in different mouse models of liver regeneration

Bozko, P

Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo

Capsaicin impairs carcinogenesis of human intra- and extrahepatic cholangiocarcinoma cells

Brandenburg, LO

Deletion of Formyl-peptide receptors lead to an increased inflammatory response and enhanced liver injury following a bacterial induced hepatitis

Braun, F

Nebenwirkungsspektrum während und nach erfolgreicher HCV Triple-Therapie nach Leberlebendtransplantation

Differentialdiagnose des hiliären Cholangiocarcinoms (Klatskin-Tumor): Extrapankreatische Form einer IgG4-positiven Autoimmunpankreatitis – Ein Fallbericht

Langzeitüberleben mit TIPS

Korrelation der nicht-invasiven ShearWave-Elastografie und der sonographisch assistierten Leberbiopsie bei der Bestimmung des Leberfibrosgrades

Sonographische Darstellung des Ductus thoracicus bei Leberzirrhose: Ein neues diagnostisches Tool?

Breitk-Heinlein, K

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Breitkopf-Heinlein, K

Cytokine secretion profile of culture-activated mouse hepatic stellate cells upon stimulation with LPS

Bremer, B

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Bremer, CM

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Brenner, D

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Breuer, M

Comparison of transient elastography, 13C-Methacetin meta-bolism, and liver biopsy for evaluation of fibrosis in chronic hepatitis C infection

Computer assisted image analysis of hepatic collagen: ASSO-ciations to metavir staging, transient elastography and 13C methacetin metabolism in patients with chronic hepatitis C infection

Breuhahn, K

Role of A20(TNFAIP3) in mediating TNFα-induced pathways activation in mouse hepatoma cell lines and primary hepatocytes

Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Nup155 is linked to the p53 pathway in HCC

Broecker-Preuß, M

Long-term maintenance of human liver tissue by ex-vivo perfusion of liver sections

Broering, R

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Human non-parenchymal liver cells produce type I and type III interferons in response to poly I:C, thereby mediating an antiviral state against HCV

Interferon stimulated gene 15, a proviral factor in hepatitis C virus replication, is regulated by the Proteasome subunit alpha type-6

Brooks, J

Resectable transgenic tumor models in mice for biliary cancers

Brückner, S

Hepatogenic differentiated murine mesenchymal stem cells display functional qualities of perivenous and/or periportal hepatocytes

Hepatocytic Differentiated Mesenchymal Stem Cells for Translational Research in the Pig

Brunner, SM

Tumor containment by immune cells and fibrotic capsule improve survival of patients following resection of colorectal liver metastasis

The regenerative capacity of the biliary epithelium influences biliary complications following liver transplantation

Bruns, T

Virus Infection Of Hepatic Sinusoidal Endothelial Cells Regulates Hepatic T Cell Recruitment And Activation

Brunskole-Hummel, I

Quality of HBsAg-specific immune memory: response to hepatitis-B-revaccination in adolescents 10 – 15 years after immunization in infancy

Bruss, V

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Brustle, A

NK cell activity promotes liver damage and chronic viral infection

Bubenheim, M

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Budhu, A

Tumor suppressive mechanisms in hepatocellular carcinoma through inhibition of IL-6 signaling

Buechler, C

Geschlechtsspezifische Expression der hepatischen Mangan-Superoxiddismutase bei der nicht alkoholische Fettlebererkrankung (NAFLD)

Buggisch, P

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

Bühler, NEM

Kontrollierter Prozess zur Generierung einer azellularisierten Lebermatrix

Burkhardt, B

Simultaneous isolation of primary human hepatocytes and non-parenchymal liver cells for the establishment of functional co-culture and tissue engineering liver models

A story about hepatic inflammatory and regenerative processes: An in vitro model of liver damage shows influence from hepatic tissue quality and donor anamnesis

Busch, HW

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

Busch, K

Comparison of different inhibitory pathways in hepatitis B virus-specific CD8+ T cell exhaustion

Buschauer, S

Doxorubicin induces tumorigenicity and chemotherapy resistance of residual hepatocellular carcinoma cells in vitro

Buti, M

Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay

Butter, A

Optimierung der Rattenleber-Dezellularisierung durch arterielle Perfusion unter oszillierenden Umgebungsdruckschwankungen

Caballero, S

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Cai, S

Screening for TGFB Signaling Regulator expression in human HCC

Calle Serrano, B

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

Calvisi, D

Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis

Calvisi, DF

Die Aktivierung der DNA-dependent protein kinase catalytic subunit führt zur Hepatokarzinogenese und ist ein Prognosefaktor des Hepatozellulären Karzinoms

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Canbay, A

MicroRNAs as Mediators in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Steatohepatitis

Long-term maintenance of human liver tissue by ex-vivo perfusion of liver sections

Offspring of high fat diet fed dams develop hepatic steatosis

Carambia, A

TREM1-Defizienz begünstigt die vorzeitige Klärung einer Virushepatitis im Mausmodell

Carlyle, JR

NK cell activity promotes liver damage and chronic viral infection

Casper, M

Primary prevention of gallbladder stones during weight loss: systematic review and meta-analysis of randomised controlled trials

Design der INCA-Studie: Impact of NOD2 genotype-guided antibiotic prevention on survival in patients with liver cirrhosis and ascites

Chamulitrat, W

Protective role of Ursodeoxycholyl Lysophosphatidylethanolamide during hepatic ischemia and reperfusion injury in mice

Phospholipase A2 controls fatty acid uptake into liver cells in a pharmacologically-responsive way

Ursodeoxycholyl Lysophosphatidyletanolamide (UDCA-LPE) modifies aberrant lipid profiles in non-alcoholic fatty liver disease

Hepatic FATP4-deficiency causes alterations in lipid metabolism

Deficiency of group via Phospholipase A2 in OB/OB mice renders protection against hepatic steatosis by reduction of VLDL secretion and alteration of phospholipid fatty acid composition

Chattergoon, MA

Monocytes Affect Natural Killer cell Antiviral IFN-γ Production in HCV Infection via Inflammasome-mediated IL-18 Secretion

Chawla, R

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

Chen, P

NK cell activity promotes liver damage and chronic viral infection

Chen, X

Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Chepa-Lotrea, X

Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection

Chmielewski, M

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Christ, B

Hepatogenic differentiated murine mesenchymal stem cells display functional qualities of perivenous and/or periportal hepatocytes

Hepatocytic Differentiated Mesenchymal Stem Cells for Translational Research in the Pig

Christiansen, H

Effect of direct single-dose irradiation on fat metabolism in rat liver: FAT/CD36 as the main responsible protein?

Churin, Y

Fibrosing cholestatic hepatitis in HBV transgenic mice after bone marrow transplantation

Signaling pathways involved in carcinogenesis in a double hit mouse model of cholangiopathy and hepatitis B virus

Spontaner Verlust der Überexpression des großen HBV-Oberflächenproteins schützt Alb1-HBV-transgene Mäuse vor Leberschädigung

Regulation der HCC Entstehung bei NASH in ApoE/LDLR Doppel-Knockout Mäusen unter Western-Diät

Cytokeratins 8 and 18 are responsible for distribution and secretion of hepatitis B virus surface proteins

Ciesek, S

Primary but not secondary biliary acids inhibit hepatitis D virus entry into human hepatoma cells expressing the sodium-taurocholate cotransporting polypeptide

Endogenous oxidized LDL levels predict treatment response in interferon-based therapy of chronic hepatitis C

Cigliano, A

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Cornberg, J

Successful triple therapy of patients with chronic hepatitis C genotype 1 infection leads to significant improvement of non-invasive liver fibrosis tests

Cornberg, M

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Successful triple therapy of patients with chronic hepatitis C genotype 1 infection leads to significant improvement of non-invasive liver fibrosis tests

Cox, AL

Monocytes Affect Natural Killer cell Antiviral IFN-γ Production in HCV Infection via Inflammasome-mediated IL-18 Secretion

Cubero, FJ

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Die CREMα-abhängige T-Zellantwort hemmt Progression der chronischen Lebererkrankung und deren Komplikationen

Fehlen von gp130 in Hepatozyten verringert die Tumorlast in einem Modell der chemisch induzierten Leberkarzinogenese

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Cubero, J

Protektive Wirkung des HGF/c-Met bei Acetaminophen induziertem Leberschaden durch Inhibierung von oxidativem Stress

Curth, HM

Expression pattern of the stem/progenitor cell marker Neighbor of Punc E 11 in different mouse models of liver regeneration

Czech, B

Expression and function of methylthioadenosine phosphorylase (MTAP) in activated hepatic stellate

Keratinocyte growth factor inhibits hepatic inflammation and fibrosis in murine models of hepatic injury

Expression and function of glucose transporter 1 (GLUT1) expression in activated hepatic stellate cells

Czock, D

Immunomonitoring of NFAT-regulated gene expression in liver allograft recipients under telaprevir based hepatitis C therapy reveals significant impact on residual gene activity

Damm, G

Simultaneous isolation of primary human hepatocytes and non-parenchymal liver cells for the establishment of functional co-culture and tissue engineering liver models

A story about hepatic inflammatory and regenerative processes: An in vitro model of liver damage shows influence from hepatic tissue quality and donor anamnesis

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Genetically engineered hepatocytes as a capable application for in vitro liver cell systems

Dammermann, W

Easy and robust testing of T cell responsiveness to HBV antigens in whole blood of chronic Hepatitis B patients

Expression of myelin auto-antigens and myelin altered peptide ligands in the liver in EAE mice models

Dandekar, T

MicroRNAs as Mediators in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Steatohepatitis

Dandri, M

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Proliferation of hepatitis B virus infected human hepatocytes in humanized mice treated with the entry inhibitor Myrcludex-B induces strong cccDNA reduction and maintenance of cccDNA-free hepatocytes

Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay

Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice

Dauch, D

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

De Bandt, JP

Einfluss von Citrullin auf die Entstehung einer Western Style Diät-induzierten nicht alkoholbedingten Fettlebererkrankung (NAFLD): Untersuchungen im Mausmodell

Decker, G

Die intratumorale Behandlung mit IL-2-exprimierenden DC inhibiert das Tumorwachstum von subkutanen HCC und steigert die Rekrutierung von regulatorischen T-Zellen im Tumorgewebe

Dediulia, T

Screening for TGFB Signaling Regulator expression in human HCC

Deest, M

Endogenous oxidized LDL levels predict treatment response in interferon-based therapy of chronic hepatitis C

de Leuw, P

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Delogu, S

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Dembek, C

HIV-1 infection impairs frequency and functionality of HBV-specific CD4 T cells in patients with chronic hepatitis B

Demmer, W

Die intratumorale Behandlung mit IL-2-exprimierenden DC inhibiert das Tumorwachstum von subkutanen HCC und steigert die Rekrutierung von regulatorischen T-Zellen im Tumorgewebe

Deng, X

Protective role of Ursodeoxycholyl Lysophosphatidylethanolamide during hepatic ischemia and reperfusion injury in mice

Deficiency of group via Phospholipase A2 in OB/OB mice renders protection against hepatic steatosis by reduction of VLDL secretion and alteration of phospholipid fatty acid composition

de Oliveira, CPMS

Primary but not secondary biliary acids inhibit hepatitis D virus entry into human hepatoma cells expressing the sodium-taurocholate cotransporting polypeptide

Deterding, K

Successful triple therapy of patients with chronic hepatitis C genotype 1 infection leads to significant improvement of non-invasive liver fibrosis tests

Dettmer, K

Expression and function of methylthioadenosine phosphorylase (MTAP) in activated hepatic stellate

Dhamodaran, A

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Dhanji, S

NK cell activity promotes liver damage and chronic viral infection

Dieckow, K

Induktion einer hepatischen Insulinresistenz durch PGE1, PGE2 und PGE3 in primären Ratten-Hepatozyten

Diefenbach, A

NK cell activity promotes liver damage and chronic viral infection

Diegeler, S

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Dieterich, D

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Dissanayake, D

NK cell activity promotes liver damage and chronic viral infection

Doernberger, V

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Dollinger, M

Hepatocytic Differentiated Mesenchymal Stem Cells for Translational Research in the Pig

Dombrowski, F

Klarzellige Herde veränderter Hepatozyten nach intraportaler Pankreasinseltransplantation – Übertragung des Rattenmodells auf die Maus

Die Aktivierung der DNA-dependent protein kinase catalytic subunit führt zur Hepatokarzinogenese und ist ein Prognosefaktor des Hepatozellulären Karzinoms

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Dooley, S

The extracellular proteinase inhibitor gene Expi is a candidate gene for hepatic fibrosis susceptibility

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Screening for TGFB Signaling Regulator expression in human HCC

Cytokine secretion profile of culture-activated mouse hepatic stellate cells upon stimulation with LPS

Decreased phosphorylated Smad3 at linker site predicts poor prognosis of patients with cholangiocarcinoma

Döring, S

Hepatic FATP4-deficiency causes alterations in lipid metabolism

Dorn, C

Hepatic steatosis enhances growth and invasiveness of hepatocellular carcinoma

Dörrbecker, J

The impact of adipokines hormones on HCV life-cycle

Draenert, R

HIV-1 infection impairs frequency and functionality of HBV-specific CD4 T cells in patients with chronic hepatitis B

Drasdo, D

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Drescher, HK

β7-Integrins and MAdCAM-1 play an opposing role during the development of Non-alcoholic steatohepatitis (NASH)

Driesch, D

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Driftmann, S

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Dropmann, A

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Screening for TGFB Signaling Regulator expression in human HCC

Düber, C

Survival analysis of proposed BCLC B subgroups in hepatocellular carcinoma patients

Ebert, M

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Egetemeyr, D

Epidemiologische Entwicklung und Genotypisierung von Patienten mit einer chronischer Hepatitis B in Deutschland: Hinweise für einen Rückgang des Genotyp A zu Gunsten des Genotyp D

Egetemeyr, DP

Wirksamkeit und Sicherheit der Triple-Therapie mit Telaprevir bei 102 Patienten mit Hepatitis C, Genotyp 1: SVR 12 Daten

Verträglichkeit und Wirksamkeit einer Telaprevir Triple-Therapie der Hepatitis C, Genotyp 1 nach Lebertransplantation – SVR 24 Daten

Eggenhofer, E

Ischämie-Reperfusions vermittelter Schaden wird durch das Leberregenerations assoziiertes Protein ALR vermittelt

Ehlting, C

The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection

Ehrlich, A

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Eibisch, M

Influence of Carbon Chain Length on Formation and Composition of Triglycerides in Free Fatty Acid- induced Steatosis

Eisenbach, C

Immunomonitoring of NFAT-regulated gene expression in liver allograft recipients under telaprevir based hepatitis C therapy reveals significant impact on residual gene activity

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Eisenbürger, S

Hepatitis C virus infection results in a reorganization of the expression pattern of ErbB receptor family members on its host cell

Hepatitis C Virus modulates TNFα-induced chemokine production and enables EGF to induce chemokine production in its host cell

Eisenhardt, M

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Eisinger, K

Geschlechtsspezifische Expression der hepatischen Mangan-Superoxiddismutase bei der nicht alkoholische Fettlebererkrankung (NAFLD)

Eissing, L

TREM1-Defizienz begünstigt die vorzeitige Klärung einer Virushepatitis im Mausmodell

Eißing, F

Wirksamkeit und Sicherheit der Tripletherapie bei chronischer Hepatitis C Virusinfektion außerhalb kontrollierter Studien

Eiteneuer, E

Sequential PAT-expression in human hepatocyte steatosis

Nup155 is linked to the p53 pathway in HCC

Elford, A

NK cell activity promotes liver damage and chronic viral infection

El Hindy, N

Decades after spontaneous HBsAg clearance the CD8+ T cell immune response is less vigorous compared to chronic hepatitis B viral infection

El Khatib, M

Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo

Capsaicin impairs carcinogenesis of human intra- and extrahepatic cholangiocarcinoma cells

End, C

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Engstler, J

Einfluss von Citrullin auf die Entstehung einer Western Style Diät-induzierten nicht alkoholbedingten Fettlebererkrankung (NAFLD): Untersuchungen im Mausmodell

Erschfeld, S

Protektive Wirkung des HGF/c-Met bei Acetaminophen induziertem Leberschaden durch Inhibierung von oxidativem Stress

β7-Integrins and MAdCAM-1 play an opposing role during the development of Non-alcoholic steatohepatitis (NASH)

Essmann, F

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Euringer, W

Efficacy and safety of transjugular intrahepatic portosystemic shunt in patients with hepatocellular carcinoma: a single center experience

Evert, M

Die Aktivierung der DNA-dependent protein kinase catalytic subunit führt zur Hepatokarzinogenese und ist ein Prognosefaktor des Hepatozellulären Karzinoms

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Factor, VM

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Fahl, M

Induktion eines alternativen Makrophagenphänotyps durch die Tumorzellen im HCC

Fairhall, EA

Hepatic trans-differentiation of pancreatic hepatocyte-progenitor cells (B-13) in a 3D high-density culture system

Fan, B

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Fehrle, C

Epidemiologische Entwicklung und Genotypisierung von Patienten mit einer chronischer Hepatitis B in Deutschland: Hinweise für einen Rückgang des Genotyp A zu Gunsten des Genotyp D

Feld, JJ

Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection

Feo, F

Die Aktivierung der DNA-dependent protein kinase catalytic subunit führt zur Hepatokarzinogenese und ist ein Prognosefaktor des Hepatozellulären Karzinoms

Fettelschoss, A

Beneficial effects on weight gain, hepatic steatosis and expression of lipogenic target genes in a murine obesity model after IL-1 type cytokine inactivation

Fichtner, S

Tumor containment by immune cells and fibrotic capsule improve survival of patients following resection of colorectal liver metastasis

Fichtner-Feigl, S

The regenerative capacity of the biliary epithelium influences biliary complications following liver transplantation

Fickert, P

Fxr-independent expression of the oncofetal marker Neighbor of Punc E11 after bile duct ligation in the adult mouse liver

Fine, J

NK cell activity promotes liver damage and chronic viral infection

Finkelmeier, F

Single measurement of hemoglobin predicts outcome of HCC patients

Severe 25-hydroxyvitamin D deficiency identifies HCC patients with a poor prognosis

Fischer-Brügge, D

Exzellentes Therapieansprechen und gute Verträglichkeit der immunsuppressiven Therapie bei älteren Patienten mit autoimmuner Hepatitis

Fleischmann-Mundt, B

Resectable transgenic tumor models in mice for biliary cancers

Fragoulis, A

Protektive Wirkung des HGF/c-Met bei Acetaminophen induziertem Leberschaden durch Inhibierung von oxidativem Stress

Frau, M

Die Aktivierung der DNA-dependent protein kinase catalytic subunit führt zur Hepatokarzinogenese und ist ein Prognosefaktor des Hepatozellulären Karzinoms

Frauenschuh, L

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Freyer, N

Hepatic differentiation of hiPSC in a 3D multicompartment bioreactor

Fried, M

Comparison of transient elastography, 13C-Methacetin meta-bolism, and liver biopsy for evaluation of fibrosis in chronic hepatitis C infection

Computer assisted image analysis of hepatic collagen: ASSO-ciations to metavir staging, transient elastography and 13C methacetin metabolism in patients with chronic hepatitis C infection

Friedrich, K

Reduction of alkaline phosphatase levels improves survival in PSC patients independent of dominant stenosis

In PSC patients the influence of cholestasis and cholangitis on CA19 – 9 serum levels depends on FUT2/3 genotype

Frischke, S

Expression des muskarinischen Acetylcholinrezeptors M3 (M3AchR) auf humanen Cholangiozyten und Einfluss von humanen Immunglobulinen auf die Rezeptoraktivität und die Zellproliferation

Fröse, N

An algorithm that predicts the viability and the yield of isolated human hepatocytes from surgical remnant tissues

Fuchs, H

ABCB4-defiziente Mäuse zeigen depressives und ängstliches Verhalten

Fulda, S

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Gaestel, M

The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection

Gailus-Durner, V

ABCB4-defiziente Mäuse zeigen depressives und ängstliches Verhalten

Galante, A

Vitamin D deficiency in primary sclerosing cholangitis is related to histological fibrosis stage at the time of diagnosis

Galle, PR

Feasibility and benefits of systemic second-line therapy in advanced hepatocellular carcinoma (HCC) – a retrospective analysis

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Survival analysis of proposed BCLC B subgroups in hepatocellular carcinoma patients

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Bedeutung des Caspase 8-Homologs cFLIP bei der metabolischen Leberschädigung

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Risk factors for acute renal impairment following orthotopic liver transplantation

Verlaufskontrolle des Fibrosegrades nach Lebertransplantation – Histologie und Transiente Elastografie mittels FibroScan im direkten Vergleich

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Garrett, L

ABCB4-defiziente Mäuse zeigen depressives und ängstliches Verhalten

Gassler, N

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Fehlen von gp130 in Hepatozyten verringert die Tumorlast in einem Modell der chemisch induzierten Leberkarzinogenese

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Gasteiger, G

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Gautheron, J

Die RIP3-abhängige Nekroptose inhibiert die inflammatorische Hepatokarzinogenese durch eine Hemmung der Caspase-8- und JNK-abhängigen kompensatorischen Zellproliferation

Gebhardt, R

Wnt-signaling gradients and their impact on liver parenchymal heterogeneity – a link to xenobiotic metabolism

TICK-TOCK-HEDGEHOG: Hedgehog signalling controls the liver circadian clock and vice versa

The lipogenic transcription factors Pparα and Pparγ as possible linkage between lipid metabolism and Hedgehog-Signalling Pathway?

Crosstalk Morphogener Signalwege im Hepatozellulären Karzinom?

Der Wnt und Hedgehog Signalweg im Leberparenchym – Ein Einblick in Zonierung und Funktion

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Influence of Carbon Chain Length on Formation and Composition of Triglycerides in Free Fatty Acid- induced Steatosis

Geffers, R

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

In vivo RNAi screen for new tumor suppressor genes in Hepatocellular Carcinoma

The Serum Reponse Factor (SRF) is involved in the transcriptional upregulation of the functional p53 inhibitor MDM 4 in hepatocellular carcinoma

Gehrke, N

Bedeutung des Caspase 8-Homologs cFLIP bei der metabolischen Leberschädigung

Geier, A

Comparison of transient elastography, 13C-Methacetin meta-bolism, and liver biopsy for evaluation of fibrosis in chronic hepatitis C infection

MicroRNAs as Mediators in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Steatohepatitis

Higher frequency of peripheral CD3CXCR3 and CD4CXCR3 positive blood cells in HCV patients in context of bile acid retention

Computer assisted image analysis of hepatic collagen: ASSO-ciations to metavir staging, transient elastography and 13C methacetin metabolism in patients with chronic hepatitis C infection

Beneficial effects on weight gain, hepatic steatosis and expression of lipogenic target genes in a murine obesity model after IL-1 type cytokine inactivation

Geipel, A

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Geisler, F

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

HIV-1 infection impairs frequency and functionality of HBV-specific CD4 T cells in patients with chronic hepatitis B

Geissler, EK

mTOR Inhibition verbessert die Effektivität der FGFR Blockade im HCC Modell

Ischämie-Reperfusions vermittelter Schaden wird durch das Leberregenerations assoziiertes Protein ALR vermittelt

Gerardy-Schahn, R

Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

Gerken, G

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

New mouse model mimicking IFN-related depression in HCV patients

Human non-parenchymal liver cells produce type I and type III interferons in response to poly I:C, thereby mediating an antiviral state against HCV

Interferon stimulated gene 15, a proviral factor in hepatitis C virus replication, is regulated by the Proteasome subunit alpha type-6

Decades after spontaneous HBsAg clearance the CD8+ T cell immune response is less vigorous compared to chronic hepatitis B viral infection

Long-term maintenance of human liver tissue by ex-vivo perfusion of liver sections

Offspring of high fat diet fed dams develop hepatic steatosis

Gertzen, C

A proximal α-helix of the TGR5 C-Terminus is essential for receptor plasma membrane localization

Ghallab, A

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Ghazarian, M

NK cell activity promotes liver damage and chronic viral infection

Giannelli, V

Changes of gene expression of different BMP-proteins in liver in different mouse and rat models of acute phase reaction

Giebeler, A

Deletion of Formyl-peptide receptors lead to an increased inflammatory response and enhanced liver injury following a bacterial induced hepatitis

Giersch, K

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Proliferation of hepatitis B virus infected human hepatocytes in humanized mice treated with the entry inhibitor Myrcludex-B induces strong cccDNA reduction and maintenance of cccDNA-free hepatocytes

Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay

Giese, T

Immunomonitoring of NFAT-regulated gene expression in liver allograft recipients under telaprevir based hepatitis C therapy reveals significant impact on residual gene activity

Gieseler, RK

Long-term maintenance of human liver tissue by ex-vivo perfusion of liver sections

Glässner, A

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

IL-8 hemmt die Suszeptibilität von CD56hochCD16negativ NK-Zellen gegenüber primären humanen hepatischen Sternzellen (HSC)

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Glebe, D

Signaling pathways involved in carcinogenesis in a double hit mouse model of cholangiopathy and hepatitis B virus

Spontaner Verlust der Überexpression des großen HBV-Oberflächenproteins schützt Alb1-HBV-transgene Mäuse vor Leberschädigung

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Cytokeratins 8 and 18 are responsible for distribution and secretion of hepatitis B virus surface proteins

Gluud, LL

Primary prevention of gallbladder stones during weight loss: systematic review and meta-analysis of randomised controlled trials

Goeppert, B

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Goeser, F

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Goeser, T

Fxr-independent expression of the oncofetal marker Neighbor of Punc E11 after bile duct ligation in the adult mouse liver

Expression pattern of the stem/progenitor cell marker Neighbor of Punc E 11 in different mouse models of liver regeneration

Goetze, O

Comparison of transient elastography, 13C-Methacetin meta-bolism, and liver biopsy for evaluation of fibrosis in chronic hepatitis C infection

Computer assisted image analysis of hepatic collagen: ASSO-ciations to metavir staging, transient elastography and 13C methacetin metabolism in patients with chronic hepatitis C infection

Gohlke, H

A proximal α-helix of the TGR5 C-Terminus is essential for receptor plasma membrane localization

Gomez-Quirez, L

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Gonzalez-Carmona, MA

Die intratumorale Behandlung mit IL-2-exprimierenden DC inhibiert das Tumorwachstum von subkutanen HCC und steigert die Rekrutierung von regulatorischen T-Zellen im Tumorgewebe

Görg, B

Seneszenzmarker in mit Ammoniak behandelten kultivierten Rattenastrozyten und post mortem Hirngewebe von Leberzirrhosepatienten mit hepatischer Enzephalopathie

Einfluss für die hepatische Enzephalopathie relevanter Faktoren auf die Expression des Multidrug Resistance Protein 4

Hepatische Enzephalopathie und Osmolyttransporter Expression in kultivierten Rattenastrozyten und im Rattenhirn

Gotthardt, D

Immunomonitoring of NFAT-regulated gene expression in liver allograft recipients under telaprevir based hepatitis C therapy reveals significant impact on residual gene activity

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Gotthardt, DN

Reduction of alkaline phosphatase levels improves survival in PSC patients independent of dominant stenosis

In PSC patients the influence of cholestasis and cholangitis on CA19 – 9 serum levels depends on FUT2/3 genotype

Götze, S

Hepatische Sternzellen unterstützen als mesenchymale Stammzellen die Regeneration der Leber

Grabski, E

The impact of adipokines hormones on HCV life-cycle

Grambihler, A

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Grasemann, C

Offspring of high fat diet fed dams develop hepatic steatosis

Graumann, F

Spontaner Verlust der Überexpression des großen HBV-Oberflächenproteins schützt Alb1-HBV-transgene Mäuse vor Leberschädigung

Gröpper, C

Hepatitis C Virus modulates TNFα-induced chemokine production and enables EGF to induce chemokine production in its host cell

Grotemeyer, K

Relevanz alter und neuer laborchemischer Parameter bei hospitalisierten Patienten mit Leberzirrhose und bakterieller Infektion

Grouls, C

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Grünhage, F

Design der INCA-Studie: Impact of NOD2 genotype-guided antibiotic prevention on survival in patients with liver cirrhosis and ascites

Frequent PNPLA3 variant determines the fate of patients with chronic liver diseases: a Liver unit experience

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Grusdat, M

NK cell activity promotes liver damage and chronic viral infection

Guardiola, J

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Guenther, R

Nebenwirkungsspektrum während und nach erfolgreicher HCV Triple-Therapie nach Leberlebendtransplantation

Differentialdiagnose des hiliären Cholangiocarcinoms (Klatskin-Tumor): Extrapankreatische Form einer IgG4-positiven Autoimmunpankreatitis – Ein Fallbericht

Langzeitüberleben mit TIPS

Korrelation der nicht-invasiven ShearWave-Elastografie und der sonographisch assistierten Leberbiopsie bei der Bestimmung des Leberfibrosgrades

Sonographische Darstellung des Ductus thoracicus bei Leberzirrhose: Ein neues diagnostisches Tool?

Guillamet, A

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Guldiken, N

Human keratin 8 variants predispose to acetaminophen hepatotoxicity

Güldiken, N

Hsp72 overexpression protects from acetaminophen and DDC-associated liver injury but enhances protein aggregation

Günter, K

Wnt-signaling gradients and their impact on liver parenchymal heterogeneity – a link to xenobiotic metabolism

Gürlevik, E

Resectable transgenic tumor models in mice for biliary cancers

Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

Guthke, R

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Haag, F

Gp210 als ein negativer prädiktiver Marker für den Verlauf der Primär Biliären Zirrhose (PBC)

Haas, U

Antifibrotic effects of CCN1/CYR61 in primary portal myofibroblasts through induction of reactive oxygen species and resulting apoptosis

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Habbe, N

Multifocal β-catenin activated hepatocellular adenomas (HCA) with malignant transformation in hepatocellular carcinoma (HCC) after abuse of anabolic steroids

Häcker, S

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Hader, Y

Geschlechtsspezifische Expression der hepatischen Mangan-Superoxiddismutase bei der nicht alkoholische Fettlebererkrankung (NAFLD)

Hafezi, M

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Hahn, T von

Primary but not secondary biliary acids inhibit hepatitis D virus entry into human hepatoma cells expressing the sodium-taurocholate cotransporting polypeptide

Endogenous oxidized LDL levels predict treatment response in interferon-based therapy of chronic hepatitis C

Hall, R

The extracellular proteinase inhibitor gene Expi is a candidate gene for hepatic fibrosis susceptibility

Hall, RA

Multiple quantitative trait locus modelling (MQM) of experimental liver fibrosis

Hansen, M

Genetically engineered hepatocytes as a capable application for in vitro liver cell systems

Hashani, M

Sequential PAT-expression in human hepatocyte steatosis

Hatting, M

Fehlen von gp130 in Hepatozyten verringert die Tumorlast in einem Modell der chemisch induzierten Leberkarzinogenese

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Häussinger, D

TGR5 (Gpbar-1) mediates cholangiocyte proliferation via ROS-Src-EGFR-ERK1/2 signaling

The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection

Fibroscan und HCC/Ascites Entstehung bei Patienten mit einer HCV induzierten Leberzirrhose: Ergebnisse einer prospektiven Studie

NK cell activity promotes liver damage and chronic viral infection

Intercellular communication of macrophages and hepatocytes and its impact on macrophage differentiation and activation

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Hepatische Sternzellen unterstützen als mesenchymale Stammzellen die Regeneration der Leber

Hepatitis C virus induced suppression of IκBζ and interference with IκBζ induced Lipocalin2 Expression

Hepatitis C virus infection results in a reorganization of the expression pattern of ErbB receptor family members on its host cell

Hepatitis C Virus modulates TNFα-induced chemokine production and enables EGF to induce chemokine production in its host cell

Seneszenzmarker in mit Ammoniak behandelten kultivierten Rattenastrozyten und post mortem Hirngewebe von Leberzirrhosepatienten mit hepatischer Enzephalopathie

Tauroursodeoxycholic acid exerts anti-apoptotic effects by a MKP-1- and PKA-dependent mechanism in rat liver

Einfluss für die hepatische Enzephalopathie relevanter Faktoren auf die Expression des Multidrug Resistance Protein 4

A proximal α-helix of the TGR5 C-Terminus is essential for receptor plasma membrane localization

Hepatische Enzephalopathie und Osmolyttransporter Expression in kultivierten Rattenastrozyten und im Rattenhirn

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Haxthausen, F von

Modulation von regulatorischen T Zellen im Mausmodell der Primär Sklerosierenden Cholangitis

Heeren, J

TREM1-Defizienz begünstigt die vorzeitige Klärung einer Virushepatitis im Mausmodell

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Heidrich, B

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Heikenwälder, M

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Die RIP3-abhängige Nekroptose inhibiert die inflammatorische Hepatokarzinogenese durch eine Hemmung der Caspase-8- und JNK-abhängigen kompensatorischen Zellproliferation

Heinemann, F

Decades after spontaneous HBsAg clearance the CD8+ T cell immune response is less vigorous compared to chronic hepatitis B viral infection

Heinemann, FM

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Heinold, A

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Heinz, M

Verlaufskontrolle des Fibrosegrades nach Lebertransplantation – Histologie und Transiente Elastografie mittels FibroScan im direkten Vergleich

Heinzmann, F

In vivo RNAi screen for new tumor suppressor genes in Hepatocellular Carcinoma

Hellerbrand, C

mTOR Inhibition verbessert die Effektivität der FGFR Blockade im HCC Modell

Expression and function of methylthioadenosine phosphorylase (MTAP) in activated hepatic stellate

Novel in vitro model for combined effects of irinotecan and free fatty acids on hepatocellular lipid accumulation and inflammation

Keratinocyte growth factor inhibits hepatic inflammation and fibrosis in murine models of hepatic injury

Protective effects of Iso-Alpha Acids (IAA) on hepatic steatosis, inflammation and fibrosis

Doxorubicin induces tumorigenicity and chemotherapy resistance of residual hepatocellular carcinoma cells in vitro

Anti-fibrogenic effects of sylimarin vary significantly in human hepatic stellate cells from different donors

CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation

Hepatic steatosis enhances growth and invasiveness of hepatocellular carcinoma

Glucose transporter isoform 1 (GLUT1) expression determines tumorigenicity of melanoma cells and their potential to form hepatic metastasis

Expression and function of glucose transporter 1 (GLUT1) expression in activated hepatic stellate cells

Hempel, M

Hepatogenic differentiated murine mesenchymal stem cells display functional qualities of perivenous and/or periportal hepatocytes

Hempt, C

Development of an in vitro co-culture system to assess the DILI-related potential of drugs

Hengel, H

The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection

Hengstler, JG

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Henkel, SG

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Hennecke, N

Restoration of Hepatitis C virus-specific CD8+ T-cell responses in patients undergoing IFN-free antiviral therapy

Hensel, A

Klarzellige Herde veränderter Hepatozyten nach intraportaler Pankreasinseltransplantation – Übertragung des Rattenmodells auf die Maus

Herkel, J

TREM1-Defizienz begünstigt die vorzeitige Klärung einer Virushepatitis im Mausmodell

Leberinfitrierende CD4 T Zellen bei der autoimmunen Hepatitis zeigen ein distinktes TH1 Profil

Modulation von regulatorischen T Zellen im Mausmodell der Primär Sklerosierenden Cholangitis

Hermann, DM

New mouse model mimicking IFN-related depression in HCV patients

Hermanns, H

Beneficial effects on weight gain, hepatic steatosis and expression of lipogenic target genes in a murine obesity model after IL-1 type cytokine inactivation

Hermanns, N

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Hermanns, NL

Die CREMα-abhängige T-Zellantwort hemmt Progression der chronischen Lebererkrankung und deren Komplikationen

Herzog, N

Genetically engineered hepatocytes as a capable application for in vitro liver cell systems

Hess, CF

Effect of direct single-dose irradiation on fat metabolism in rat liver: FAT/CD36 as the main responsible protein?

Hilgard, G

Decades after spontaneous HBsAg clearance the CD8+ T cell immune response is less vigorous compared to chronic hepatitis B viral infection

Hill, A

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

Hillebrandt, K

Optimierung der Rattenleber-Dezellularisierung durch arterielle Perfusion unter oszillierenden Umgebungsdruckschwankungen

Hiller, T

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Hinrichsen, H

Langzeitüberleben mit TIPS

Ho, C

Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis

Hochrath, K

ABCB4-defiziente Mäuse zeigen depressives und ängstliches Verhalten

Hoehme, S

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Hoenicke, L

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

Hoerauf, A

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Hoffman, A

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Hoffmann, SA

Hepatic trans-differentiation of pancreatic hepatocyte-progenitor cells (B-13) in a 3D high-density culture system

Hoffmann, V

Fxr-independent expression of the oncofetal marker Neighbor of Punc E11 after bile duct ligation in the adult mouse liver

Expression pattern of the stem/progenitor cell marker Neighbor of Punc E 11 in different mouse models of liver regeneration

Hofmann, U

Wnt-signaling gradients and their impact on liver parenchymal heterogeneity – a link to xenobiotic metabolism

Hoh, A

Dominance of cytolytic effector functions in hepatitis B virus-specific CD8+ T cell and NK cell mediated antiviral efficacy using hepatitis B virus infected hepatocytes overexpressing human sodium taurocholate cotransporting polypeptide

Comparison of different inhibitory pathways in hepatitis B virus-specific CD8+ T cell exhaustion

Hohmeyer, A

In vivo RNAi screen for new tumor suppressor genes in Hepatocellular Carcinoma

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

Hölter, SM

ABCB4-defiziente Mäuse zeigen depressives und ängstliches Verhalten

Holzer, K

Nup155 is linked to the p53 pathway in HCC

Homs, M

Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay

Höner zu Siederdissen, C

Successful triple therapy of patients with chronic hepatitis C genotype 1 infection leads to significant improvement of non-invasive liver fibrosis tests

Hoppe-Lotichius, M

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Risk factors for acute renal impairment following orthotopic liver transplantation

Horst, AK

The limonoids TR4 and TR9 induce apoptosis in mouse and human hepatoma cell lines

Horwitz, E

Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis

Hov, JR

In PSC patients the influence of cholestasis and cholangitis on CA19 – 9 serum levels depends on FUT2/3 genotype

Hoyo-Becerra, C

New mouse model mimicking IFN-related depression in HCV patients

Hrabě de Angelis, M

ABCB4-defiziente Mäuse zeigen depressives und ängstliches Verhalten

Hu, W

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Huang, LR

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Hübener, P

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Huber, S

Modulation von regulatorischen T Zellen im Mausmodell der Primär Sklerosierenden Cholangitis

Hubscher, S

Virus Infection Of Hepatic Sinusoidal Endothelial Cells Regulates Hepatic T Cell Recruitment And Activation

Hügging, K

The impact of adipokines hormones on HCV life-cycle

Hüppe, D

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

Ickenstein, L

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Ingiliz, P

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Itzel, T

Screening for TGFB Signaling Regulator expression in human HCC

Verlaufskontrolle des Fibrosegrades nach Lebertransplantation – Histologie und Transiente Elastografie mittels FibroScan im direkten Vergleich

Jahn, A

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Jahn-Hofmann, K

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Jain, MK

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

James, LP

Human keratin 8 variants predispose to acetaminophen hepatotoxicity

Janciauskiene, S

Alpha-1-Antitrypsin inhibits acute liver failure in mice

Janicot, M

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Jara, M

Einfluss Oxaliplatin-haltiger Chemotherapie auf die Leberfunktion – Ein Fallbericht

Jaschinski, F

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Jedicke, N

Alpha-1-Antitrypsin inhibits acute liver failure in mice

Jeiter, T

Tumor containment by immune cells and fibrotic capsule improve survival of patients following resection of colorectal liver metastasis

Jiang, L

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Jilg, W

Quality of HBsAg-specific immune memory: response to hepatitis-B-revaccination in adolescents 10 – 15 years after immunization in infancy

Decline in Hepatitis E Virus (HEV) Antibody Prevalence in Southeastern Germany, 1996 – 2011

Jin, C

Einfluss von Citrullin auf die Entstehung einer Western Style Diät-induzierten nicht alkoholbedingten Fettlebererkrankung (NAFLD): Untersuchungen im Mausmodell

Jochum, C

Decades after spontaneous HBsAg clearance the CD8+ T cell immune response is less vigorous compared to chronic hepatitis B viral infection

Joerdens, MS

Einfluss für die hepatische Enzephalopathie relevanter Faktoren auf die Expression des Multidrug Resistance Protein 4

John, K

NAFLD staging by an improved ELISA for serum cytokeratin-18 fragments

John, M

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Johnstone, RW

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Junger, H

The regenerative capacity of the biliary epithelium influences biliary complications following liver transplantation

Jüngst, C

Intrahepatic cholestasis-associated ATP8B1 variation underlying protracted cholestatic course of acute hepatitis E virus infection

Kaech, SM

NK cell activity promotes liver damage and chronic viral infection

Kah, J

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice

Kahraman, A

Decades after spontaneous HBsAg clearance the CD8+ T cell immune response is less vigorous compared to chronic hepatitis B viral infection

Kaldenbach, M

Protektive Wirkung des HGF/c-Met bei Acetaminophen induziertem Leberschaden durch Inhibierung von oxidativem Stress

Kalinke, U

The impact of adipokines hormones on HCV life-cycle

Kampschulte, M

Regulation der HCC Entstehung bei NASH in ApoE/LDLR Doppel-Knockout Mäusen unter Western-Diät

Kang, TW

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

In vivo RNAi screen for new tumor suppressor genes in Hepatocellular Carcinoma

Development of shRNA transgenic mice for preclinical studies of the MKK4 regeneration kinase

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

Karababa, A

Seneszenzmarker in mit Ammoniak behandelten kultivierten Rattenastrozyten und post mortem Hirngewebe von Leberzirrhosepatienten mit hepatischer Enzephalopathie

Karimi, K

Maternal Liver Damage Programs Offspring Allergic Inflammation in Mice

Kataev, V

Nebenwirkungsspektrum während und nach erfolgreicher HCV Triple-Therapie nach Leberlebendtransplantation

Kefalakes, H

Decades after spontaneous HBsAg clearance the CD8+ T cell immune response is less vigorous compared to chronic hepatitis B viral infection

Kegel, V

Simultaneous isolation of primary human hepatocytes and non-parenchymal liver cells for the establishment of functional co-culture and tissue engineering liver models

A story about hepatic inflammatory and regenerative processes: An in vitro model of liver damage shows influence from hepatic tissue quality and donor anamnesis

Keitel, V

TGR5 (Gpbar-1) mediates cholangiocyte proliferation via ROS-Src-EGFR-ERK1/2 signaling

Einfluss für die hepatische Enzephalopathie relevanter Faktoren auf die Expression des Multidrug Resistance Protein 4

A proximal α-helix of the TGR5 C-Terminus is essential for receptor plasma membrane localization

Kemmerling, R

Additive anti-Tumor Response to the Rabbit VX2 Hepatoma by Combined Radio Frequency Ablation and Toll like Receptor 9 Stimulation

Kemper, T

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Kempinska, A

Individuals with the PNPLA3 (adiponutrin) variant present with unexpected body fat composition: a study in one thousand healthy blood donors

Kern, M

TICK-TOCK-HEDGEHOG: Hedgehog signalling controls the liver circadian clock and vice versa

Kesselring, R

Tumor containment by immune cells and fibrotic capsule improve survival of patients following resection of colorectal liver metastasis

Kessler, T

Maternal Liver Damage Programs Offspring Allergic Inflammation in Mice

Kiesslich, R

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Kiessling, F

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Kircheis, G

Fibroscan und HCC/Ascites Entstehung bei Patienten mit einer HCV induzierten Leberzirrhose: Ergebnisse einer prospektiven Studie

Kirschner, J

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

Successful triple therapy of patients with chronic hepatitis C genotype 1 infection leads to significant improvement of non-invasive liver fibrosis tests

Kitade, M

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Kittner, J

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Klak, M

Individuals with the PNPLA3 (adiponutrin) variant present with unexpected body fat composition: a study in one thousand healthy blood donors

Klawonn, F

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

Klein, R

Aktivierung von T-Helferzellen durch Sulfitoxidase (SO), einem Autoantigen bei der primär-sklerosierenden Cholangitis (PSC)

Expression des muskarinischen Acetylcholinrezeptors M3 (M3AchR) auf humanen Cholangiozyten und Einfluss von humanen Immunglobulinen auf die Rezeptoraktivität und die Zellproliferation

Nachweis von funktionellen Autoantikörpern gegen den muskarinischen Acetylcholinrezeptor M3 (M3AchR) in Seren von Patienten mit autoimmunen Lebererkrankungen

Klein, S

Mas-Receptor Überexpression in (mREN2)27 Ratten nach Leberschädigung ist protektiv für die Fibrose und portale Hypertension

Die JAK2-Hemmung senkt den Pfortaderdruck in einem genetischen NASH-Modell der Ratte

Kleinehr, K

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Human non-parenchymal liver cells produce type I and type III interferons in response to poly I:C, thereby mediating an antiviral state against HCV

Interferon stimulated gene 15, a proviral factor in hepatitis C virus replication, is regulated by the Proteasome subunit alpha type-6

Klinker, H

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

Higher frequency of peripheral CD3CXCR3 and CD4CXCR3 positive blood cells in HCV patients in context of bile acid retention

Kloos, A

Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

Klose, C

NK cell activity promotes liver damage and chronic viral infection

Klöting, N

TICK-TOCK-HEDGEHOG: Hedgehog signalling controls the liver circadian clock and vice versa

Knierim, J

In PSC patients the influence of cholestasis and cholangitis on CA19 – 9 serum levels depends on FUT2/3 genotype

Knolle, P

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Cytokine secretion profile of culture-activated mouse hepatic stellate cells upon stimulation with LPS

Knöspel, F

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Hepatic differentiation of hiPSC in a 3D multicompartment bioreactor

Knüppel, E

Efficacy and safety of transjugular intrahepatic portosystemic shunt in patients with hepatocellular carcinoma: a single center experience

Köberle, V

Single measurement of hemoglobin predicts outcome of HCC patients

Severe 25-hydroxyvitamin D deficiency identifies HCC patients with a poor prognosis

Koch, A

Erhöhte miR-122 Serumkonzentration stellen einen Biomarker für einen Leberschaden bei kritisch kranken Patienten dar

Hepatic steatosis enhances growth and invasiveness of hepatocellular carcinoma

Glucose transporter isoform 1 (GLUT1) expression determines tumorigenicity of melanoma cells and their potential to form hepatic metastasis

Koch, S

Feasibility and benefits of systemic second-line therapy in advanced hepatocellular carcinoma (HCC) – a retrospective analysis

Survival analysis of proposed BCLC B subgroups in hepatocellular carcinoma patients

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Risk factors for acute renal impairment following orthotopic liver transplantation

koczan, D

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Koenigsrainer, A

Decreased phosphorylated Smad3 at linker site predicts poor prognosis of patients with cholangiocarcinoma

Koenigsrainer, I

Decreased phosphorylated Smad3 at linker site predicts poor prognosis of patients with cholangiocarcinoma

Kohring, M

Easy and robust testing of T cell responsiveness to HBV antigens in whole blood of chronic Hepatitis B patients

Kokordelis, P

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Königsrainer, A

Kontrollierter Prozess zur Generierung einer azellularisierten Lebermatrix

Verträglichkeit und Wirksamkeit einer Telaprevir Triple-Therapie der Hepatitis C, Genotyp 1 nach Lebertransplantation – SVR 24 Daten

Köpke, A

Differentialdiagnose des hiliären Cholangiocarcinoms (Klatskin-Tumor): Extrapankreatische Form einer IgG4-positiven Autoimmunpankreatitis – Ein Fallbericht

Sonographische Darstellung des Ductus thoracicus bei Leberzirrhose: Ein neues diagnostisches Tool?

Kordes, C

Hepatische Sternzellen unterstützen als mesenchymale Stammzellen die Regeneration der Leber

Korhonen, H

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Kort, J

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Kotobi, AN

Early lactate clearance as predictor of initial poor graft function after liver transplantation – a confirmative study

Kozik, JH

TREM1-Defizienz begünstigt die vorzeitige Klärung einer Virushepatitis im Mausmodell

Krämer, B

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

IL-8 hemmt die Suszeptibilität von CD56hochCD16negativ NK-Zellen gegenüber primären humanen hepatischen Sternzellen (HSC)

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Krautbauer, S

Geschlechtsspezifische Expression der hepatischen Mangan-Superoxiddismutase bei der nicht alkoholische Fettlebererkrankung (NAFLD)

Krawczyk, M

Frequent PNPLA3 variant determines the fate of patients with chronic liver diseases: a Liver unit experience

Individuals with the PNPLA3 (adiponutrin) variant present with unexpected body fat composition: a study in one thousand healthy blood donors

Krebs, K

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Kronenberger, B

Single measurement of hemoglobin predicts outcome of HCC patients

Severe 25-hydroxyvitamin D deficiency identifies HCC patients with a poor prognosis

Kroy, D

Protektive Wirkung des HGF/c-Met bei Acetaminophen induziertem Leberschaden durch Inhibierung von oxidativem Stress

Kroy, DC

β7-Integrins and MAdCAM-1 play an opposing role during the development of Non-alcoholic steatohepatitis (NASH)

Krupp, M

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Kubicka, S

Resectable transgenic tumor models in mice for biliary cancers

Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses

Kucukoglu, O

Human keratin 8 variants predispose to acetaminophen hepatotoxicity

Kudlich, T

Higher frequency of peripheral CD3CXCR3 and CD4CXCR3 positive blood cells in HCV patients in context of bile acid retention

Kühnel, F

Resectable transgenic tumor models in mice for biliary cancers

Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses

Kukolj, G

Restoration of Hepatitis C virus-specific CD8+ T-cell responses in patients undergoing IFN-free antiviral therapy

Kündig, T

Beneficial effects on weight gain, hepatic steatosis and expression of lipogenic target genes in a murine obesity model after IL-1 type cytokine inactivation

Küpper, JH

Genetically engineered hepatocytes as a capable application for in vitro liver cell systems

Lahiri, P

Hsp72 overexpression protects from acetaminophen and DDC-associated liver injury but enhances protein aggregation

Lambertz, D

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Lammert, F

The extracellular proteinase inhibitor gene Expi is a candidate gene for hepatic fibrosis susceptibility

Primary prevention of gallbladder stones during weight loss: systematic review and meta-analysis of randomised controlled trials

Design der INCA-Studie: Impact of NOD2 genotype-guided antibiotic prevention on survival in patients with liver cirrhosis and ascites

Frequent PNPLA3 variant determines the fate of patients with chronic liver diseases: a Liver unit experience

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Multiple quantitative trait locus modelling (MQM) of experimental liver fibrosis

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

ABCB4-defiziente Mäuse zeigen depressives und ängstliches Verhalten

Intrahepatic cholestasis-associated ATP8B1 variation underlying protracted cholestatic course of acute hepatitis E virus infection

Individuals with the PNPLA3 (adiponutrin) variant present with unexpected body fat composition: a study in one thousand healthy blood donors

Relevanz alter und neuer laborchemischer Parameter bei hospitalisierten Patienten mit Leberzirrhose und bakterieller Infektion

Lampe, J

Secondary resistances to measles virus (MeV)-based virotherapy

Lang, H

Survival analysis of proposed BCLC B subgroups in hepatocellular carcinoma patients

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Risk factors for acute renal impairment following orthotopic liver transplantation

Lang, KS

NK cell activity promotes liver damage and chronic viral infection

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Lang, PA

NK cell activity promotes liver damage and chronic viral infection

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Lang, SA

mTOR Inhibition verbessert die Effektivität der FGFR Blockade im HCC Modell

Lange, N

The limonoids TR4 and TR9 induce apoptosis in mouse and human hepatoma cell lines

Langhans, B

IL-8 hemmt die Suszeptibilität von CD56hochCD16negativ NK-Zellen gegenüber primären humanen hepatischen Sternzellen (HSC)

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Laubender, RP

An algorithm that predicts the viability and the yield of isolated human hepatocytes from surgical remnant tissues

Lauer, UM

Wirksamkeit und Sicherheit der Triple-Therapie mit Telaprevir bei 102 Patienten mit Hepatitis C, Genotyp 1: SVR 12 Daten

Secondary resistances to measles virus (MeV)-based virotherapy

Different 5-FC prodrug application regimes result in different oncolytic efficiencies

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Verträglichkeit und Wirksamkeit einer Telaprevir Triple-Therapie der Hepatitis C, Genotyp 1 nach Lebertransplantation – SVR 24 Daten

Laufer, S

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

Le, VTK

The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection

Lee, SML

An algorithm that predicts the viability and the yield of isolated human hepatocytes from surgical remnant tissues

Lehnen, E

TGF-β1 modulates LPS-induced NLRP3 inflammasome activity

Leitzmann, MF

Decline in Hepatitis E Virus (HEV) Antibody Prevalence in Southeastern Germany, 1996 – 2011

Lenzen, H

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Levada, K

Hsp72 overexpression protects from acetaminophen and DDC-associated liver injury but enhances protein aggregation

Li, J

Decreased phosphorylated Smad3 at linker site predicts poor prognosis of patients with cholangiocarcinoma

Li, KK

Virus Infection Of Hepatic Sinusoidal Endothelial Cells Regulates Hepatic T Cell Recruitment And Activation

Liang, JT

Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection

Liebe, R

The extracellular proteinase inhibitor gene Expi is a candidate gene for hepatic fibrosis susceptibility

Cytokine secretion profile of culture-activated mouse hepatic stellate cells upon stimulation with LPS

Liebisch, G

Ursodeoxycholyl Lysophosphatidyletanolamide (UDCA-LPE) modifies aberrant lipid profiles in non-alcoholic fatty liver disease

Deficiency of group via Phospholipase A2 in OB/OB mice renders protection against hepatic steatosis by reduction of VLDL secretion and alteration of phospholipid fatty acid composition

Liedtke, C

Fehlen von gp130 in Hepatozyten verringert die Tumorlast in einem Modell der chemisch induzierten Leberkarzinogenese

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Liese, J

Gibt es prädiktive Parameter für das frühe HCC-Rezidiv nach Lebertransplantation?

Lietdke, C

Die CREMα-abhängige T-Zellantwort hemmt Progression der chronischen Lebererkrankung und deren Komplikationen

Lindenmaier, H

Multifocal β-catenin activated hepatocellular adenomas (HCA) with malignant transformation in hepatocellular carcinoma (HCC) after abuse of anabolic steroids

Liu, ZJ

New mouse model mimicking IFN-related depression in HCV patients

Lock, JF

Early lactate clearance as predictor of initial poor graft function after liver transplantation – a confirmative study

Einfluss Oxaliplatin-haltiger Chemotherapie auf die Leberfunktion – Ein Fallbericht

Lohmann, V

Monocytes Affect Natural Killer cell Antiviral IFN-γ Production in HCV Infection via Inflammasome-mediated IL-18 Secretion

Lohmeyer, J

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Lohse, AW

Wirksamkeit und Sicherheit der Tripletherapie bei chronischer Hepatitis C Virusinfektion außerhalb kontrollierter Studien

TREM1-Defizienz begünstigt die vorzeitige Klärung einer Virushepatitis im Mausmodell

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Leberbiopsien bei Verdacht auf Primär Sklerosierender Cholangitis (PSC) – hilfreich oder unnötig?

Exzellentes Therapieansprechen und gute Verträglichkeit der immunsuppressiven Therapie bei älteren Patienten mit autoimmuner Hepatitis

Leberinfitrierende CD4 T Zellen bei der autoimmunen Hepatitis zeigen ein distinktes TH1 Profil

Modulation von regulatorischen T Zellen im Mausmodell der Primär Sklerosierenden Cholangitis

Gp210 als ein negativer prädiktiver Marker für den Verlauf der Primär Biliären Zirrhose (PBC)

Proliferation of hepatitis B virus infected human hepatocytes in humanized mice treated with the entry inhibitor Myrcludex-B induces strong cccDNA reduction and maintenance of cccDNA-free hepatocytes

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay

Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice

Easy and robust testing of T cell responsiveness to HBV antigens in whole blood of chronic Hepatitis B patients

Induktion eines alternativen Makrophagenphänotyps durch die Tumorzellen im HCC

Vitamin D deficiency in primary sclerosing cholangitis is related to histological fibrosis stage at the time of diagnosis

Long, EL

Tumor suppressive mechanisms in hepatocellular carcinoma through inhibition of IL-6 signaling

Longerich, T

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

Multifocal β-catenin activated hepatocellular adenomas (HCA) with malignant transformation in hepatocellular carcinoma (HCC) after abuse of anabolic steroids

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

In vivo RNAi screen for new tumor suppressor genes in Hepatocellular Carcinoma

The Serum Reponse Factor (SRF) is involved in the transcriptional upregulation of the functional p53 inhibitor MDM 4 in hepatocellular carcinoma

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

Lonjon-Domanec, I

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

Loscher, C

Identification of HO-1/CO-induced tumor protective genes in HCC

Lowe, S

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

Lowe, SW

Development of shRNA transgenic mice for preclinical studies of the MKK4 regeneration kinase

Lu, M

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Luch, A

Development of an in vitro co-culture system to assess the DILI-related potential of drugs

Luedde, T

Erhöhte miR-122 Serumkonzentration stellen einen Biomarker für einen Leberschaden bei kritisch kranken Patienten dar

Die RIP3-abhängige Nekroptose inhibiert die inflammatorische Hepatokarzinogenese durch eine Hemmung der Caspase-8- und JNK-abhängigen kompensatorischen Zellproliferation

Lühr, CS

Induktion eines alternativen Makrophagenphänotyps durch die Tumorzellen im HCC

Lupke, M

Geschlechtsspezifische Expression der hepatischen Mangan-Superoxiddismutase bei der nicht alkoholische Fettlebererkrankung (NAFLD)

Reduktion von Lipo-apoptose in Abhängigkeit der Lokalisation und Isoform des hepatoprotektiven Protein ALR

Palmitinsäure induzierter lipoxischer ER-Stress und Lipo-apoptose wird durch das hepatoprotektive Protein ALR vermindert

Ischämie-Reperfusions vermittelter Schaden wird durch das Leberregenerations assoziiertes Protein ALR vermittelt

Lütgehetmann, M

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Proliferation of hepatitis B virus infected human hepatocytes in humanized mice treated with the entry inhibitor Myrcludex-B induces strong cccDNA reduction and maintenance of cccDNA-free hepatocytes

Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay

Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice

Lüth, S

Wirksamkeit und Sicherheit der Tripletherapie bei chronischer Hepatitis C Virusinfektion außerhalb kontrollierter Studien

Easy and robust testing of T cell responsiveness to HBV antigens in whole blood of chronic Hepatitis B patients

Expression of myelin auto-antigens and myelin altered peptide ligands in the liver in EAE mice models

Lutterbeck, M

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Human non-parenchymal liver cells produce type I and type III interferons in response to poly I:C, thereby mediating an antiviral state against HCV

Interferon stimulated gene 15, a proviral factor in hepatitis C virus replication, is regulated by the Proteasome subunit alpha type-6

Lutz, P

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Lutz, PL

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Maasoumy, B

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

Successful triple therapy of patients with chronic hepatitis C genotype 1 infection leads to significant improvement of non-invasive liver fibrosis tests

Mahli, A

Novel in vitro model for combined effects of irinotecan and free fatty acids on hepatocellular lipid accumulation and inflammation

Protective effects of Iso-Alpha Acids (IAA) on hepatic steatosis, inflammation and fibrosis

Anti-fibrogenic effects of sylimarin vary significantly in human hepatic stellate cells from different donors

CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation

Mak, TW

NK cell activity promotes liver damage and chronic viral infection

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Malek, N

Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

Alpha-1-Antitrypsin inhibits acute liver failure in mice

Capsaicin impairs carcinogenesis of human intra- and extrahepatic cholangiocarcinoma cells

Malek, NP

Wirksamkeit und Sicherheit der Triple-Therapie mit Telaprevir bei 102 Patienten mit Hepatitis C, Genotyp 1: SVR 12 Daten

Secondary resistances to measles virus (MeV)-based virotherapy

Different 5-FC prodrug application regimes result in different oncolytic efficiencies

Epidemiologische Entwicklung und Genotypisierung von Patienten mit einer chronischer Hepatitis B in Deutschland: Hinweise für einen Rückgang des Genotyp A zu Gunsten des Genotyp D

Development of shRNA transgenic mice for preclinical studies of the MKK4 regeneration kinase

Verträglichkeit und Wirksamkeit einer Telaprevir Triple-Therapie der Hepatitis C, Genotyp 1 nach Lebertransplantation – SVR 24 Daten

Malik, I

Changes of gene expression of different BMP-proteins in liver in different mouse and rat models of acute phase reaction

Malik, IA

Role of the Hypoxia Inducible Factors HIF-1α and HIF-2α during hepatic repair in a rat model of thioacetamide (TAA)-induced chronic liver damage

Effect of direct single-dose irradiation on fat metabolism in rat liver: FAT/CD36 as the main responsible protein?

Differential localization of transferrin receptors and lipocalin-2 in rat hepatic and extra-hepatic organs during acute phase response

Mallolas, J

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Manero, M

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Mann, A

Bedeutung des Caspase 8-Homologs cFLIP bei der metabolischen Leberschädigung

Manns, M

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

NAFLD staging by an improved ELISA for serum cytokeratin-18 fragments

Manns, MP

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

The impact of adipokines hormones on HCV life-cycle

Resectable transgenic tumor models in mice for biliary cancers

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Primary but not secondary biliary acids inhibit hepatitis D virus entry into human hepatoma cells expressing the sodium-taurocholate cotransporting polypeptide

Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

Endogenous oxidized LDL levels predict treatment response in interferon-based therapy of chronic hepatitis C

Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses

Successful triple therapy of patients with chronic hepatitis C genotype 1 infection leads to significant improvement of non-invasive liver fibrosis tests

Mansmann, U

An algorithm that predicts the viability and the yield of isolated human hepatocytes from surgical remnant tissues

Marbach, E

Wnt-signaling gradients and their impact on liver parenchymal heterogeneity – a link to xenobiotic metabolism

TICK-TOCK-HEDGEHOG: Hedgehog signalling controls the liver circadian clock and vice versa

Marin, JJG

Higher frequency of peripheral CD3CXCR3 and CD4CXCR3 positive blood cells in HCV patients in context of bile acid retention

Markova, AA

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

Marks, K

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Marquardt, JU

Feasibility and benefits of systemic second-line therapy in advanced hepatocellular carcinoma (HCC) – a retrospective analysis

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Martin, B

Restoration of Hepatitis C virus-specific CD8+ T-cell responses in patients undergoing IFN-free antiviral therapy

A protective HLA-B*27 restricted epitope contributes to viral control in chronic HCV infection despite presence of viral escape mutations and is characterized by a unique T cell phenotype

Martin, M

Tumor containment by immune cells and fibrotic capsule improve survival of patients following resection of colorectal liver metastasis

Martin, R

Leberinfitrierende CD4 T Zellen bei der autoimmunen Hepatitis zeigen ein distinktes TH1 Profil

Martius, G

Effect of direct single-dose irradiation on fat metabolism in rat liver: FAT/CD36 as the main responsible protein?

Mathe, Z

Long-term maintenance of human liver tissue by ex-vivo perfusion of liver sections

Matono, T

Signaling pathways involved in carcinogenesis in a double hit mouse model of cholangiopathy and hepatitis B virus

Matz-Soja, M

Wnt-signaling gradients and their impact on liver parenchymal heterogeneity – a link to xenobiotic metabolism

TICK-TOCK-HEDGEHOG: Hedgehog signalling controls the liver circadian clock and vice versa

Der Wnt und Hedgehog Signalweg im Leberparenchym – Ein Einblick in Zonierung und Funktion

Influence of Carbon Chain Length on Formation and Composition of Triglycerides in Free Fatty Acid- induced Steatosis

Mauss, S

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

McJunkin, K

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

Mcllwain, DR

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Mehrabi, A

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Meindl-Beinker, N

Screening for TGFB Signaling Regulator expression in human HCC

Melter, M

Reduktion von Lipo-apoptose in Abhängigkeit der Lokalisation und Isoform des hepatoprotektiven Protein ALR

Palmitinsäure induzierter lipoxischer ER-Stress und Lipo-apoptose wird durch das hepatoprotektive Protein ALR vermindert

Ischämie-Reperfusions vermittelter Schaden wird durch das Leberregenerations assoziiertes Protein ALR vermittelt

Meltzer, P

Tumor suppressive mechanisms in hepatocellular carcinoma through inhibition of IL-6 signaling

Menzel, N

The impact of adipokines hormones on HCV life-cycle

Meurer, S

Hepatic stellate cell specific endoglin deletion modulates TGF-β signaling and aggravates liver fibrosis in two experimental models of murine liver injury

Meurer, SK

Impact of soluble Endoglin on TGF-β1 mediated immediate early responses in HepG2 cells

Antifibrotic effects of CCN1/CYR61 in primary portal myofibroblasts through induction of reactive oxygen species and resulting apoptosis

Differential regulation of Id1 expression by TGF-β1 in HepG2 cells

Meyer, C

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Michael, MP

Alpha-1-Antitrypsin inhibits acute liver failure in mice

Michl, P

Additive anti-Tumor Response to the Rabbit VX2 Hepatoma by Combined Radio Frequency Ablation and Toll like Receptor 9 Stimulation

Michler, T

Correlation of fulminant hepatitis B and escape mutations in the 2nd loop of the HBsAg a-determinant

Milera, H

Verlaufskontrolle des Fibrosegrades nach Lebertransplantation – Histologie und Transiente Elastografie mittels FibroScan im direkten Vergleich

Milkiewicz, M

Individuals with the PNPLA3 (adiponutrin) variant present with unexpected body fat composition: a study in one thousand healthy blood donors

Milkiewicz, P

Individuals with the PNPLA3 (adiponutrin) variant present with unexpected body fat composition: a study in one thousand healthy blood donors

Mittler, J

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Mix, C

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

Mo, FR

Hsp72 overexpression protects from acetaminophen and DDC-associated liver injury but enhances protein aggregation

Moench, C

Gibt es prädiktive Parameter für das frühe HCC-Rezidiv nach Lebertransplantation?

Mohs, A

Die CREMα-abhängige T-Zellantwort hemmt Progression der chronischen Lebererkrankung und deren Komplikationen

Moldenhauer, G

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Mollenhauer, J

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Momburg, F

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Monga, SPS

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Moriconi, F

Role of the Hypoxia Inducible Factors HIF-1α and HIF-2α during hepatic repair in a rat model of thioacetamide (TAA)-induced chronic liver damage

Differential localization of transferrin receptors and lipocalin-2 in rat hepatic and extra-hepatic organs during acute phase response

Changes of gene expression of different BMP-proteins in liver in different mouse and rat models of acute phase reaction

Moro, N

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Morten, CH

Fxr-independent expression of the oncofetal marker Neighbor of Punc E11 after bile duct ligation in the adult mouse liver

Moss, PA

Virus Infection Of Hepatic Sinusoidal Endothelial Cells Regulates Hepatic T Cell Recruitment And Activation

Muller, M

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Müller, E

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Müller, M

Expression and function of methylthioadenosine phosphorylase (MTAP) in activated hepatic stellate

Novel in vitro model for combined effects of irinotecan and free fatty acids on hepatocellular lipid accumulation and inflammation

Protective effects of Iso-Alpha Acids (IAA) on hepatic steatosis, inflammation and fibrosis

CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation

Hepatic steatosis enhances growth and invasiveness of hepatocellular carcinoma

Expression and function of glucose transporter 1 (GLUT1) expression in activated hepatic stellate cells

Müller-Schilling, M

Anti-fibrogenic effects of sylimarin vary significantly in human hepatic stellate cells from different donors

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Müller-Vieira, U

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Müllhaupt, B

Comparison of transient elastography, 13C-Methacetin meta-bolism, and liver biopsy for evaluation of fibrosis in chronic hepatitis C infection

MicroRNAs as Mediators in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Steatohepatitis

Higher frequency of peripheral CD3CXCR3 and CD4CXCR3 positive blood cells in HCV patients in context of bile acid retention

Computer assisted image analysis of hepatic collagen: ASSO-ciations to metavir staging, transient elastography and 13C methacetin metabolism in patients with chronic hepatitis C infection

Beneficial effects on weight gain, hepatic steatosis and expression of lipogenic target genes in a murine obesity model after IL-1 type cytokine inactivation

Munker, S

Decreased phosphorylated Smad3 at linker site predicts poor prognosis of patients with cholangiocarcinoma

Nadalin, S

Verträglichkeit und Wirksamkeit einer Telaprevir Triple-Therapie der Hepatitis C, Genotyp 1 nach Lebertransplantation – SVR 24 Daten

Decreased phosphorylated Smad3 at linker site predicts poor prognosis of patients with cholangiocarcinoma

Nagel, M

Bedeutung des Caspase 8-Homologs cFLIP bei der metabolischen Leberschädigung

Nattermann, J

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

IL-8 hemmt die Suszeptibilität von CD56hochCD16negativ NK-Zellen gegenüber primären humanen hepatischen Sternzellen (HSC)

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Nault, JC

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

Naz, N

Role of the Hypoxia Inducible Factors HIF-1α and HIF-2α during hepatic repair in a rat model of thioacetamide (TAA)-induced chronic liver damage

Differential localization of transferrin receptors and lipocalin-2 in rat hepatic and extra-hepatic organs during acute phase response

Changes of gene expression of different BMP-proteins in liver in different mouse and rat models of acute phase reaction

Nelson, M

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Neß, M

Impact of soluble Endoglin on TGF-β1 mediated immediate early responses in HepG2 cells

Neuhaus, P

Einfluss Oxaliplatin-haltiger Chemotherapie auf die Leberfunktion – Ein Fallbericht

Neumann, U

Deletion of Formyl-peptide receptors lead to an increased inflammatory response and enhanced liver injury following a bacterial induced hepatitis

Neumann-Haefelin, C

A protective HLA-B*27 restricted epitope contributes to viral control in chronic HCV infection despite presence of viral escape mutations and is characterized by a unique T cell phenotype

Neureiter, D

Additive anti-Tumor Response to the Rabbit VX2 Hepatoma by Combined Radio Frequency Ablation and Toll like Receptor 9 Stimulation

Nevzorova, YA

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Ni, Y

Dominance of cytolytic effector functions in hepatitis B virus-specific CD8+ T cell and NK cell mediated antiviral efficacy using hepatitis B virus infected hepatocytes overexpressing human sodium taurocholate cotransporting polypeptide

Nierhoff, D

Fxr-independent expression of the oncofetal marker Neighbor of Punc E11 after bile duct ligation in the adult mouse liver

Expression pattern of the stem/progenitor cell marker Neighbor of Punc E 11 in different mouse models of liver regeneration

Niesler, B

MicroRNAs as Mediators in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Steatohepatitis

Nischalke, HD

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Nitschke, K

A protective HLA-B*27 restricted epitope contributes to viral control in chronic HCV infection despite presence of viral escape mutations and is characterized by a unique T cell phenotype

Nittka, S

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Nkengfack, AE

The limonoids TR4 and TR9 induce apoptosis in mouse and human hepatoma cell lines

Noels, H

β7-Integrins and MAdCAM-1 play an opposing role during the development of Non-alcoholic steatohepatitis (NASH)

Nordheim, A

The Serum Reponse Factor (SRF) is involved in the transcriptional upregulation of the functional p53 inhibitor MDM 4 in hepatocellular carcinoma

Nübling, T

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Nunez, M

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Nüssler, A

Simultaneous isolation of primary human hepatocytes and non-parenchymal liver cells for the establishment of functional co-culture and tissue engineering liver models

A story about hepatic inflammatory and regenerative processes: An in vitro model of liver damage shows influence from hepatic tissue quality and donor anamnesis

Nüssler, AK

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Oefner, P

Expression and function of methylthioadenosine phosphorylase (MTAP) in activated hepatic stellate

Oehler, N

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Oellsner, J

Comparison of transient elastography, 13C-Methacetin meta-bolism, and liver biopsy for evaluation of fibrosis in chronic hepatitis C infection

Computer assisted image analysis of hepatic collagen: ASSO-ciations to metavir staging, transient elastography and 13C methacetin metabolism in patients with chronic hepatitis C infection

Oenarto, J

Hepatische Enzephalopathie und Osmolyttransporter Expression in kultivierten Rattenastrozyten und im Rattenhirn

Offermanns, S

Nachweis von funktionellen Autoantikörpern gegen den muskarinischen Acetylcholinrezeptor M3 (M3AchR) in Seren von Patienten mit autoimmunen Lebererkrankungen

Ohashi, PS

NK cell activity promotes liver damage and chronic viral infection

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Ohl, K

Die CREMα-abhängige T-Zellantwort hemmt Progression der chronischen Lebererkrankung und deren Komplikationen

Omary, MB

Human keratin 8 variants predispose to acetaminophen hepatotoxicity

Ori, A

Nup155 is linked to the p53 pathway in HCC

Ostroumov, D

Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses

Otto, G

Survival analysis of proposed BCLC B subgroups in hepatocellular carcinoma patients

Risk factors for acute renal impairment following orthotopic liver transplantation

Pachnio, A

Virus Infection Of Hepatic Sinusoidal Endothelial Cells Regulates Hepatic T Cell Recruitment And Activation

Palagani, V

Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo

Capsaicin impairs carcinogenesis of human intra- and extrahepatic cholangiocarcinoma cells

Palmert, M

Offspring of high fat diet fed dams develop hepatic steatosis

Pandyra, AA

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Parcina, M

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Parish, I

NK cell activity promotes liver damage and chronic viral infection

Pascale, RM

Die Aktivierung der DNA-dependent protein kinase catalytic subunit führt zur Hepatokarzinogenese und ist ein Prognosefaktor des Hepatozellulären Karzinoms

Pathil, A

Protective role of Ursodeoxycholyl Lysophosphatidylethanolamide during hepatic ischemia and reperfusion injury in mice

Ursodeoxycholyl Lysophosphatidyletanolamide (UDCA-LPE) modifies aberrant lipid profiles in non-alcoholic fatty liver disease

Pathil-Warth, A

Phospholipase A2 controls fatty acid uptake into liver cells in a pharmacologically-responsive way

Paul, A

Human non-parenchymal liver cells produce type I and type III interferons in response to poly I:C, thereby mediating an antiviral state against HCV

Pawella, LM

Sequential PAT-expression in human hepatocyte steatosis

Pellegrino, R

The Serum Reponse Factor (SRF) is involved in the transcriptional upregulation of the functional p53 inhibitor MDM 4 in hepatocellular carcinoma

Peng, J

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Pereira, IVA

Primary but not secondary biliary acids inhibit hepatitis D virus entry into human hepatoma cells expressing the sodium-taurocholate cotransporting polypeptide

Pesic, M

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

Development of shRNA transgenic mice for preclinical studies of the MKK4 regeneration kinase

Petersen, J

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Proliferation of hepatitis B virus infected human hepatocytes in humanized mice treated with the entry inhibitor Myrcludex-B induces strong cccDNA reduction and maintenance of cccDNA-free hepatocytes

Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay

Petri, M

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Peveling-Oberhag, J

Gibt es prädiktive Parameter für das frühe HCC-Rezidiv nach Lebertransplantation?

Pfaender, S

The impact of adipokines hormones on HCV life-cycle

Pfaff, CM

Hsp72 overexpression protects from acetaminophen and DDC-associated liver injury but enhances protein aggregation

Pfaff, M

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Pfarr, K

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Pfeiffer, E

Simultaneous isolation of primary human hepatocytes and non-parenchymal liver cells for the establishment of functional co-culture and tissue engineering liver models

A story about hepatic inflammatory and regenerative processes: An in vitro model of liver damage shows influence from hepatic tissue quality and donor anamnesis

Pietschmann, T

The impact of adipokines hormones on HCV life-cycle

Piiper, A

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Single measurement of hemoglobin predicts outcome of HCC patients

Severe 25-hydroxyvitamin D deficiency identifies HCC patients with a poor prognosis

Pikarsky, E

Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis

Pinna, F

Role of A20(TNFAIP3) in mediating TNFα-induced pathways activation in mouse hepatoma cell lines and primary hepatocytes

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Plankenhorn, S

Aktivierung von T-Helferzellen durch Sulfitoxidase (SO), einem Autoantigen bei der primär-sklerosierenden Cholangitis (PSC)

Plentz, R

Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo

Capsaicin impairs carcinogenesis of human intra- and extrahepatic cholangiocarcinoma cells

Ploch, PS

Verlaufskontrolle des Fibrosegrades nach Lebertransplantation – Histologie und Transiente Elastografie mittels FibroScan im direkten Vergleich

Ploeger, C

Tumor suppressive mechanisms in hepatocellular carcinoma through inhibition of IL-6 signaling

Poggenpohl, L

Interferon stimulated gene 15, a proviral factor in hepatitis C virus replication, is regulated by the Proteasome subunit alpha type-6

Port, K

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

Successful triple therapy of patients with chronic hepatitis C genotype 1 infection leads to significant improvement of non-invasive liver fibrosis tests

Premsrirut, PK

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

Development of shRNA transgenic mice for preclinical studies of the MKK4 regeneration kinase

Preuß, BE

Aktivierung von T-Helferzellen durch Sulfitoxidase (SO), einem Autoantigen bei der primär-sklerosierenden Cholangitis (PSC)

Expression des muskarinischen Acetylcholinrezeptors M3 (M3AchR) auf humanen Cholangiozyten und Einfluss von humanen Immunglobulinen auf die Rezeptoraktivität und die Zellproliferation

Nachweis von funktionellen Autoantikörpern gegen den muskarinischen Acetylcholinrezeptor M3 (M3AchR) in Seren von Patienten mit autoimmunen Lebererkrankungen

Protzer, U

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Correlation of fulminant hepatitis B and escape mutations in the 2nd loop of the HBsAg a-determinant

HIV-1 infection impairs frequency and functionality of HBV-specific CD4 T cells in patients with chronic hepatitis B

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Przibilla, J

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Puoti, M

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Püschel, GP

Induktion einer hepatischen Insulinresistenz durch PGE1, PGE2 und PGE3 in primären Ratten-Hepatozyten

Quaas, A

Leberbiopsien bei Verdacht auf Primär Sklerosierender Cholangitis (PSC) – hilfreich oder unnötig?

Modulation von regulatorischen T Zellen im Mausmodell der Primär Sklerosierenden Cholangitis

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

An additional heme oxygenase-1 knockout increases systemic inflammation and fibrosis in MDR2 knockout mice

Induktion eines alternativen Makrophagenphänotyps durch die Tumorzellen im HCC

Vitamin D deficiency in primary sclerosing cholangitis is related to histological fibrosis stage at the time of diagnosis

Quitt, O

Immunotherapeutic retargeting of effector cells towards HBV infected target cells using bispecific antibody constructs

Rahbar, R

NK cell activity promotes liver damage and chronic viral infection

Ramadori, G

Role of the Hypoxia Inducible Factors HIF-1α and HIF-2α during hepatic repair in a rat model of thioacetamide (TAA)-induced chronic liver damage

Effect of direct single-dose irradiation on fat metabolism in rat liver: FAT/CD36 as the main responsible protein?

Differential localization of transferrin receptors and lipocalin-2 in rat hepatic and extra-hepatic organs during acute phase response

Changes of gene expression of different BMP-proteins in liver in different mouse and rat models of acute phase reaction

Ramadori, P

Role of the Hypoxia Inducible Factors HIF-1α and HIF-2α during hepatic repair in a rat model of thioacetamide (TAA)-induced chronic liver damage

Ramisch, K

Maternal Liver Damage Programs Offspring Allergic Inflammation in Mice

Ranganathan, S

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Raschzok, N

Optimierung der Rattenleber-Dezellularisierung durch arterielle Perfusion unter oszillierenden Umgebungsdruckschwankungen

Rath, T

Regulation der HCC Entstehung bei NASH in ApoE/LDLR Doppel-Knockout Mäusen unter Western-Diät

Rau, M

Higher frequency of peripheral CD3CXCR3 and CD4CXCR3 positive blood cells in HCV patients in context of bile acid retention

Rauber, P

Relevanz alter und neuer laborchemischer Parameter bei hospitalisierten Patienten mit Leberzirrhose und bakterieller Infektion

Rave-Fränk, M

Effect of direct single-dose irradiation on fat metabolism in rat liver: FAT/CD36 as the main responsible protein?

Real, CI

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Interferon stimulated gene 15, a proviral factor in hepatitis C virus replication, is regulated by the Proteasome subunit alpha type-6

Recher, M

NK cell activity promotes liver damage and chronic viral infection

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Rehermann, B

Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection

Monocytes Affect Natural Killer cell Antiviral IFN-γ Production in HCV Infection via Inflammasome-mediated IL-18 Secretion

Rehm, M

Human keratin 8 variants predispose to acetaminophen hepatotoxicity

Reich, M

TGR5 (Gpbar-1) mediates cholangiocyte proliferation via ROS-Src-EGFR-ERK1/2 signaling

Reinehr, R

Tauroursodeoxycholic acid exerts anti-apoptotic effects by a MKP-1- and PKA-dependent mechanism in rat liver

Reinhard, H

Signaling pathways involved in carcinogenesis in a double hit mouse model of cholangiopathy and hepatitis B virus

Reiser, J

Secondary resistances to measles virus (MeV)-based virotherapy

Reisinger, F

Die RIP3-abhängige Nekroptose inhibiert die inflammatorische Hepatokarzinogenese durch eine Hemmung der Caspase-8- und JNK-abhängigen kompensatorischen Zellproliferation

Reiter, F

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Renner, M

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Rey, JW

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Reynolds, G

Virus Infection Of Hepatic Sinusoidal Endothelial Cells Regulates Hepatic T Cell Recruitment And Activation

Ribback, S

Klarzellige Herde veränderter Hepatozyten nach intraportaler Pankreasinseltransplantation – Übertragung des Rattenmodells auf die Maus

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Richter, M

Hepatic trans-differentiation of pancreatic hepatocyte-progenitor cells (B-13) in a 3D high-density culture system

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Rockstroh, JK

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Roderburg, C

Erhöhte miR-122 Serumkonzentration stellen einen Biomarker für einen Leberschaden bei kritisch kranken Patienten dar

Die RIP3-abhängige Nekroptose inhibiert die inflammatorische Hepatokarzinogenese durch eine Hemmung der Caspase-8- und JNK-abhängigen kompensatorischen Zellproliferation

Roderfeld, M

Fibrosing cholestatic hepatitis in HBV transgenic mice after bone marrow transplantation

Signaling pathways involved in carcinogenesis in a double hit mouse model of cholangiopathy and hepatitis B virus

Spontaner Verlust der Überexpression des großen HBV-Oberflächenproteins schützt Alb1-HBV-transgene Mäuse vor Leberschädigung

Regulation der HCC Entstehung bei NASH in ApoE/LDLR Doppel-Knockout Mäusen unter Western-Diät

Cytokeratins 8 and 18 are responsible for distribution and secretion of hepatitis B virus surface proteins

Rodríguez Romero, M

Higher frequency of peripheral CD3CXCR3 and CD4CXCR3 positive blood cells in HCV patients in context of bile acid retention

Roeb, E

Fibrosing cholestatic hepatitis in HBV transgenic mice after bone marrow transplantation

Signaling pathways involved in carcinogenesis in a double hit mouse model of cholangiopathy and hepatitis B virus

Spontaner Verlust der Überexpression des großen HBV-Oberflächenproteins schützt Alb1-HBV-transgene Mäuse vor Leberschädigung

Regulation der HCC Entstehung bei NASH in ApoE/LDLR Doppel-Knockout Mäusen unter Western-Diät

Cytokeratins 8 and 18 are responsible for distribution and secretion of hepatitis B virus surface proteins

Roessler, S

Tumor suppressive mechanisms in hepatocellular carcinoma through inhibition of IL-6 signaling

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Rogalska-Taranta, M

The impact of adipokines hormones on HCV life-cycle

Rohr, F

Development of an in vitro co-culture system to assess the DILI-related potential of drugs

Roos, K

Immunomonitoring of NFAT-regulated gene expression in liver allograft recipients under telaprevir based hepatitis C therapy reveals significant impact on residual gene activity

Rössle, M

Efficacy and safety of transjugular intrahepatic portosystemic shunt in patients with hepatocellular carcinoma: a single center experience

Rößler, A

Reduction of alkaline phosphatase levels improves survival in PSC patients independent of dominant stenosis

Rotman, Y

Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection

Rubner, C

Tumor containment by immune cells and fibrotic capsule improve survival of patients following resection of colorectal liver metastasis

Rudalska, R

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

Ruemmele, P

Geschlechtsspezifische Expression der hepatischen Mangan-Superoxiddismutase bei der nicht alkoholische Fettlebererkrankung (NAFLD)

Tumor containment by immune cells and fibrotic capsule improve survival of patients following resection of colorectal liver metastasis

The regenerative capacity of the biliary epithelium influences biliary complications following liver transplantation

Rupp, C

Reduction of alkaline phosphatase levels improves survival in PSC patients independent of dominant stenosis

In PSC patients the influence of cholestasis and cholangitis on CA19 – 9 serum levels depends on FUT2/3 genotype

Russo, C

Correlation of fulminant hepatitis B and escape mutations in the 2nd loop of the HBsAg a-determinant

HIV-1 infection impairs frequency and functionality of HBV-specific CD4 T cells in patients with chronic hepatitis B

Rust, C

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Ryschich, E

Avidity and shear stress-linked anchoring to tumor endothelium: transfer the principles of leukocyte adhesion for tumor-specific drug delivery

Sagir, A

Fibroscan und HCC/Ascites Entstehung bei Patienten mit einer HCV induzierten Leberzirrhose: Ergebnisse einer prospektiven Studie

Sahin, H

Hepatic stellate cell specific endoglin deletion modulates TGF-β signaling and aggravates liver fibrosis in two experimental models of murine liver injury

Sales, S

Influence of Carbon Chain Length on Formation and Composition of Triglycerides in Free Fatty Acid- induced Steatosis

Salih, HR

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Samarin, J

Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis

Sandmann, M

An additional heme oxygenase-1 knockout increases systemic inflammation and fibrosis in MDR2 knockout mice

Sarrazin, C

Primary but not secondary biliary acids inhibit hepatitis D virus entry into human hepatoma cells expressing the sodium-taurocholate cotransporting polypeptide

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Endogenous oxidized LDL levels predict treatment response in interferon-based therapy of chronic hepatitis C

Sass, G

An additional heme oxygenase-1 knockout increases systemic inflammation and fibrosis in MDR2 knockout mice

Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice

Identification of HO-1/CO-induced tumor protective genes in HCC

The limonoids TR4 and TR9 induce apoptosis in mouse and human hepatoma cell lines

Sauer, I

Optimierung der Rattenleber-Dezellularisierung durch arterielle Perfusion unter oszillierenden Umgebungsdruckschwankungen

Sauer, P

Reduction of alkaline phosphatase levels improves survival in PSC patients independent of dominant stenosis

Sauerbruch, T

Mas-Receptor Überexpression in (mREN2)27 Ratten nach Leberschädigung ist protektiv für die Fibrose und portale Hypertension

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Die intratumorale Behandlung mit IL-2-exprimierenden DC inhibiert das Tumorwachstum von subkutanen HCC und steigert die Rekrutierung von regulatorischen T-Zellen im Tumorgewebe

Die JAK2-Hemmung senkt den Pfortaderdruck in einem genetischen NASH-Modell der Ratte

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Sawitza, I

Hepatische Sternzellen unterstützen als mesenchymale Stammzellen die Regeneration der Leber

Schad, A

Bedeutung des Caspase 8-Homologs cFLIP bei der metabolischen Leberschädigung

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Schaefer, F

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Schaefer, P

Langzeitüberleben mit TIPS

Schaffrath, C

Antifibrotic effects of CCN1/CYR61 in primary portal myofibroblasts through induction of reactive oxygen species and resulting apoptosis

Schattenberg, J

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Schattenberg, JM

Bedeutung des Caspase 8-Homologs cFLIP bei der metabolischen Leberschädigung

Schelcher, C

An algorithm that predicts the viability and the yield of isolated human hepatocytes from surgical remnant tissues

Scheller, T

mTOR Inhibition verbessert die Effektivität der FGFR Blockade im HCC Modell

Schemmerer, M

Decline in Hepatitis E Virus (HEV) Antibody Prevalence in Southeastern Germany, 1996 – 2011

Schenk, M

Kontrollierter Prozess zur Generierung einer azellularisierten Lebermatrix

Scherbaum, N

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Schiergens, TS

An algorithm that predicts the viability and the yield of isolated human hepatocytes from surgical remnant tissues

Schierwagen, R

Mas-Receptor Überexpression in (mREN2)27 Ratten nach Leberschädigung ist protektiv für die Fibrose und portale Hypertension

Die JAK2-Hemmung senkt den Pfortaderdruck in einem genetischen NASH-Modell der Ratte

Schievenbusch, S

Fxr-independent expression of the oncofetal marker Neighbor of Punc E11 after bile duct ligation in the adult mouse liver

Expression pattern of the stem/progenitor cell marker Neighbor of Punc E 11 in different mouse models of liver regeneration

Schildberg, F

Cytokine secretion profile of culture-activated mouse hepatic stellate cells upon stimulation with LPS

Schildgen, J

Identification of HO-1/CO-induced tumor protective genes in HCC

Schiller, J

Influence of Carbon Chain Length on Formation and Composition of Triglycerides in Free Fatty Acid- induced Steatosis

Schippers, A

β7-Integrins and MAdCAM-1 play an opposing role during the development of Non-alcoholic steatohepatitis (NASH)

Schirmacher, P

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

Multifocal β-catenin activated hepatocellular adenomas (HCA) with malignant transformation in hepatocellular carcinoma (HCC) after abuse of anabolic steroids

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

Role of A20(TNFAIP3) in mediating TNFα-induced pathways activation in mouse hepatoma cell lines and primary hepatocytes

Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis

In vivo RNAi screen for new tumor suppressor genes in Hepatocellular Carcinoma

Sequential PAT-expression in human hepatocyte steatosis

The Serum Reponse Factor (SRF) is involved in the transcriptional upregulation of the functional p53 inhibitor MDM 4 in hepatocellular carcinoma

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Nup155 is linked to the p53 pathway in HCC

Schirmbeck, R

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Schlaak, JF

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

New mouse model mimicking IFN-related depression in HCV patients

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Human non-parenchymal liver cells produce type I and type III interferons in response to poly I:C, thereby mediating an antiviral state against HCV

Interferon stimulated gene 15, a proviral factor in hepatitis C virus replication, is regulated by the Proteasome subunit alpha type-6

Schließ, F

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Schlitt, HJ

mTOR Inhibition verbessert die Effektivität der FGFR Blockade im HCC Modell

Ischämie-Reperfusions vermittelter Schaden wird durch das Leberregenerations assoziiertes Protein ALR vermittelt

Tumor containment by immune cells and fibrotic capsule improve survival of patients following resection of colorectal liver metastasis

The regenerative capacity of the biliary epithelium influences biliary complications following liver transplantation

Schlue, J

Leberbiopsien bei Verdacht auf Primär Sklerosierender Cholangitis (PSC) – hilfreich oder unnötig?

Schmetz, A

Frequent PNPLA3 variant determines the fate of patients with chronic liver diseases: a Liver unit experience

Schmidt, K

mTOR Inhibition verbessert die Effektivität der FGFR Blockade im HCC Modell

Schmidt-Heck, W

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Schmitt, J

MicroRNAs as Mediators in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Steatohepatitis

Higher frequency of peripheral CD3CXCR3 and CD4CXCR3 positive blood cells in HCV patients in context of bile acid retention

Beneficial effects on weight gain, hepatic steatosis and expression of lipogenic target genes in a murine obesity model after IL-1 type cytokine inactivation

Schmitz, G

Ursodeoxycholyl Lysophosphatidyletanolamide (UDCA-LPE) modifies aberrant lipid profiles in non-alcoholic fatty liver disease

Deficiency of group via Phospholipase A2 in OB/OB mice renders protection against hepatic steatosis by reduction of VLDL secretion and alteration of phospholipid fatty acid composition

Schnitzbauer, A

Gibt es prädiktive Parameter für das frühe HCC-Rezidiv nach Lebertransplantation?

Schnitzler, P

Immunomonitoring of NFAT-regulated gene expression in liver allograft recipients under telaprevir based hepatitis C therapy reveals significant impact on residual gene activity

Scholten, D

Hepatic stellate cell specific endoglin deletion modulates TGF-β signaling and aggravates liver fibrosis in two experimental models of murine liver injury

Optimization purity of isolated primary liver endothelial cells (LSEC) using adenoviral gene transfer

Schönefeld, K

Der Wnt und Hedgehog Signalweg im Leberparenchym – Ein Einblick in Zonierung und Funktion

Schott, E

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Schrader, J

Induktion eines alternativen Makrophagenphänotyps durch die Tumorzellen im HCC

Schramm, C

Leberbiopsien bei Verdacht auf Primär Sklerosierender Cholangitis (PSC) – hilfreich oder unnötig?

Exzellentes Therapieansprechen und gute Verträglichkeit der immunsuppressiven Therapie bei älteren Patienten mit autoimmuner Hepatitis

Leberinfitrierende CD4 T Zellen bei der autoimmunen Hepatitis zeigen ein distinktes TH1 Profil

Modulation von regulatorischen T Zellen im Mausmodell der Primär Sklerosierenden Cholangitis

Gp210 als ein negativer prädiktiver Marker für den Verlauf der Primär Biliären Zirrhose (PBC)

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Vitamin D deficiency in primary sclerosing cholangitis is related to histological fibrosis stage at the time of diagnosis

Schreiter, T

Long-term maintenance of human liver tissue by ex-vivo perfusion of liver sections

Schröder, D

Signaling pathways involved in carcinogenesis in a double hit mouse model of cholangiopathy and hepatitis B virus

Spontaner Verlust der Überexpression des großen HBV-Oberflächenproteins schützt Alb1-HBV-transgene Mäuse vor Leberschädigung

Cytokeratins 8 and 18 are responsible for distribution and secretion of hepatitis B virus surface proteins

Schubert, F

Hepatic trans-differentiation of pancreatic hepatocyte-progenitor cells (B-13) in a 3D high-density culture system

Schuch, A

Dominance of cytolytic effector functions in hepatitis B virus-specific CD8+ T cell and NK cell mediated antiviral efficacy using hepatitis B virus infected hepatocytes overexpressing human sodium taurocholate cotransporting polypeptide

Schultheiß, M

Efficacy and safety of transjugular intrahepatic portosystemic shunt in patients with hepatocellular carcinoma: a single center experience

Single measurement of hemoglobin predicts outcome of HCC patients

Schulz, A

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Schulz, T

A story about hepatic inflammatory and regenerative processes: An in vitro model of liver damage shows influence from hepatic tissue quality and donor anamnesis

Schulze, F

Multifocal β-catenin activated hepatocellular adenomas (HCA) with malignant transformation in hepatocellular carcinoma (HCC) after abuse of anabolic steroids

Schulze, K

Leberbiopsien bei Verdacht auf Primär Sklerosierender Cholangitis (PSC) – hilfreich oder unnötig?

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Schulze-Bergkamen, H

Survival analysis of proposed BCLC B subgroups in hepatocellular carcinoma patients

Schulze-Osthoff, K

Kontrollierter Prozess zur Generierung einer azellularisierten Lebermatrix

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

NAFLD staging by an improved ELISA for serum cytokeratin-18 fragments

Schulze zur Wiesch, J

Wirksamkeit und Sicherheit der Tripletherapie bei chronischer Hepatitis C Virusinfektion außerhalb kontrollierter Studien

Easy and robust testing of T cell responsiveness to HBV antigens in whole blood of chronic Hepatitis B patients

Schumacher, F

Protektive Wirkung des HGF/c-Met bei Acetaminophen induziertem Leberschaden durch Inhibierung von oxidativem Stress

Schuppan, D

Additive anti-Tumor Response to the Rabbit VX2 Hepatoma by Combined Radio Frequency Ablation and Toll like Receptor 9 Stimulation

Schwinge, D

Modulation von regulatorischen T Zellen im Mausmodell der Primär Sklerosierenden Cholangitis

Sebode, M

Exzellentes Therapieansprechen und gute Verträglichkeit der immunsuppressiven Therapie bei älteren Patienten mit autoimmuner Hepatitis

Leberinfitrierende CD4 T Zellen bei der autoimmunen Hepatitis zeigen ein distinktes TH1 Profil

Seeger, M

Langzeitüberleben mit TIPS

Korrelation der nicht-invasiven ShearWave-Elastografie und der sonographisch assistierten Leberbiopsie bei der Bestimmung des Leberfibrosgrades

Sonographische Darstellung des Ductus thoracicus bei Leberzirrhose: Ein neues diagnostisches Tool?

Seehofer, D

Simultaneous isolation of primary human hepatocytes and non-parenchymal liver cells for the establishment of functional co-culture and tissue engineering liver models

A story about hepatic inflammatory and regenerative processes: An in vitro model of liver damage shows influence from hepatic tissue quality and donor anamnesis

Genetically engineered hepatocytes as a capable application for in vitro liver cell systems

Seeßle, J

Hepatic FATP4-deficiency causes alterations in lipid metabolism

Seifert, CR

Hepatitis C Virus modulates TNFα-induced chemokine production and enables EGF to induce chemokine production in its host cell

Selke, A

Optimierung der Rattenleber-Dezellularisierung durch arterielle Perfusion unter oszillierenden Umgebungsdruckschwankungen

Sellge, G

Fehlen von gp130 in Hepatozyten verringert die Tumorlast in einem Modell der chemisch induzierten Leberkarzinogenese

Sellmann, C

Einfluss von Citrullin auf die Entstehung einer Western Style Diät-induzierten nicht alkoholbedingten Fettlebererkrankung (NAFLD): Untersuchungen im Mausmodell

Serti, E

Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection

Monocytes Affect Natural Killer cell Antiviral IFN-γ Production in HCV Infection via Inflammasome-mediated IL-18 Secretion

Shaabani, N

NK cell activity promotes liver damage and chronic viral infection

Shevchenko, A

Influence of Carbon Chain Length on Formation and Composition of Triglycerides in Free Fatty Acid- induced Steatosis

Sichler, M

Decline in Hepatitis E Virus (HEV) Antibody Prevalence in Southeastern Germany, 1996 – 2011

Siemann, H

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Singer, S

Nup155 is linked to the p53 pathway in HCC

Sipos, B

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Decreased phosphorylated Smad3 at linker site predicts poor prognosis of patients with cholangiocarcinoma

Smirnow, I

Secondary resistances to measles virus (MeV)-based virotherapy

Solbach, P

Endogenous oxidized LDL levels predict treatment response in interferon-based therapy of chronic hepatitis C

Sollik, L

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

Sommerfeld, A

TGR5 (Gpbar-1) mediates cholangiocyte proliferation via ROS-Src-EGFR-ERK1/2 signaling

Tauroursodeoxycholic acid exerts anti-apoptotic effects by a MKP-1- and PKA-dependent mechanism in rat liver

Sonke, J

Klarzellige Herde veränderter Hepatozyten nach intraportaler Pankreasinseltransplantation – Übertragung des Rattenmodells auf die Maus

Sonntag, R

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Soriano, V

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Sospedra, M

Leberinfitrierende CD4 T Zellen bei der autoimmunen Hepatitis zeigen ein distinktes TH1 Profil

Sowa, J

Long-term maintenance of human liver tissue by ex-vivo perfusion of liver sections

Sowa, JP

Offspring of high fat diet fed dams develop hepatic steatosis

Spangenberg, HC

Efficacy and safety of transjugular intrahepatic portosystemic shunt in patients with hepatocellular carcinoma: a single center experience

Spannbauer, M

Fehlen von gp130 in Hepatozyten verringert die Tumorlast in einem Modell der chemisch induzierten Leberkarzinogenese

Spengler, U

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

IL-8 hemmt die Suszeptibilität von CD56hochCD16negativ NK-Zellen gegenüber primären humanen hepatischen Sternzellen (HSC)

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Sperling, S

Genetically engineered hepatocytes as a capable application for in vitro liver cell systems

Spieker, S

Reduktion von Lipo-apoptose in Abhängigkeit der Lokalisation und Isoform des hepatoprotektiven Protein ALR

Spitzley, S

Hepatitis C virus induced suppression of IκBζ and interference with IκBζ induced Lipocalin2 Expression

Spomer, L

A proximal α-helix of the TGR5 C-Terminus is essential for receptor plasma membrane localization

Sprinzl, M

Survival analysis of proposed BCLC B subgroups in hepatocellular carcinoma patients

Sprinzl, MF

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Risk factors for acute renal impairment following orthotopic liver transplantation

Staffer, S

Phospholipase A2 controls fatty acid uptake into liver cells in a pharmacologically-responsive way

Stein, I

Stabilization of protumorigenic FUSE binding proteins (FBPs) in hepatocarcinogenesis

Steinmann, E

The impact of adipokines hormones on HCV life-cycle

Stenzinger, A

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Stern, J

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Sterzer, V

Hepatic stellate cell specific endoglin deletion modulates TGF-β signaling and aggravates liver fibrosis in two experimental models of murine liver injury

Optimization purity of isolated primary liver endothelial cells (LSEC) using adenoviral gene transfer

Stiefel, J

Fibrosing cholestatic hepatitis in HBV transgenic mice after bone marrow transplantation

Stiel, EM

Easy and robust testing of T cell responsiveness to HBV antigens in whole blood of chronic Hepatitis B patients

Stock, P

Hepatogenic differentiated murine mesenchymal stem cells display functional qualities of perivenous and/or periportal hepatocytes

Hepatocytic Differentiated Mesenchymal Stem Cells for Translational Research in the Pig

Stockmann, M

Early lactate clearance as predictor of initial poor graft function after liver transplantation – a confirmative study

Einfluss Oxaliplatin-haltiger Chemotherapie auf die Leberfunktion – Ein Fallbericht

Stokes, CS

Primary prevention of gallbladder stones during weight loss: systematic review and meta-analysis of randomised controlled trials

ABCB4-defiziente Mäuse zeigen depressives und ängstliches Verhalten

Stoltzfus, J

Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection

Strahl, N

Hepatic differentiation of hiPSC in a 3D multicompartment bioreactor

Strassburg, C

IL-8 hemmt die Suszeptibilität von CD56hochCD16negativ NK-Zellen gegenüber primären humanen hepatischen Sternzellen (HSC)

Strassburg, CP

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

Polymorphsims in the farnesoid X receptor modify the risk for spontaneous bacterial peritonitis in cirrhotic patients

Die intratumorale Behandlung mit IL-2-exprimierenden DC inhibiert das Tumorwachstum von subkutanen HCC und steigert die Rekrutierung von regulatorischen T-Zellen im Tumorgewebe

Impact of rifaximin on the frequency and characteristics of spontaneous bacterial peritonitis in patients with liver cirrhosis and ascites

Straub, BK

Sequential PAT-expression in human hepatocyte steatosis

Streetz, K

Protektive Wirkung des HGF/c-Met bei Acetaminophen induziertem Leberschaden durch Inhibierung von oxidativem Stress

Streetz, KL

β7-Integrins and MAdCAM-1 play an opposing role during the development of Non-alcoholic steatohepatitis (NASH)

Stremmel, W

Immunomonitoring of NFAT-regulated gene expression in liver allograft recipients under telaprevir based hepatitis C therapy reveals significant impact on residual gene activity

Protective role of Ursodeoxycholyl Lysophosphatidylethanolamide during hepatic ischemia and reperfusion injury in mice

Phospholipase A2 controls fatty acid uptake into liver cells in a pharmacologically-responsive way

Ursodeoxycholyl Lysophosphatidyletanolamide (UDCA-LPE) modifies aberrant lipid profiles in non-alcoholic fatty liver disease

Hepatic FATP4-deficiency causes alterations in lipid metabolism

Reduction of alkaline phosphatase levels improves survival in PSC patients independent of dominant stenosis

In PSC patients the influence of cholestasis and cholangitis on CA19 – 9 serum levels depends on FUT2/3 genotype

Deficiency of group via Phospholipase A2 in OB/OB mice renders protection against hepatic steatosis by reduction of VLDL secretion and alteration of phospholipid fatty acid composition

Strnad, P

Human keratin 8 variants predispose to acetaminophen hepatotoxicity

Hsp72 overexpression protects from acetaminophen and DDC-associated liver injury but enhances protein aggregation

Struecker, B

Optimierung der Rattenleber-Dezellularisierung durch arterielle Perfusion unter oszillierenden Umgebungsdruckschwankungen

Struever, N

Alpha-1-Antitrypsin inhibits acute liver failure in mice

Stubenrauch, F

Secondary resistances to measles virus (MeV)-based virotherapy

Tacke, F

Erhöhte miR-122 Serumkonzentration stellen einen Biomarker für einen Leberschaden bei kritisch kranken Patienten dar

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Die RIP3-abhängige Nekroptose inhibiert die inflammatorische Hepatokarzinogenese durch eine Hemmung der Caspase-8- und JNK-abhängigen kompensatorischen Zellproliferation

Tao, J

Synergistische Effekte von Beta-Catenin und YAP führen zur Entstehung von Hepatoblastomen in Mäusen und beim Menschen

Tasika, E

Maternal Liver Damage Programs Offspring Allergic Inflammation in Mice

Tautenhahn, M

Hepatocytic Differentiated Mesenchymal Stem Cells for Translational Research in the Pig

Tenbrock, K

Die CREMα-abhängige T-Zellantwort hemmt Progression der chronischen Lebererkrankung und deren Komplikationen

ten Dijke, P

Screening for TGFB Signaling Regulator expression in human HCC

Tennstedt, P

Leberbiopsien bei Verdacht auf Primär Sklerosierender Cholangitis (PSC) – hilfreich oder unnötig?

Teufel, A

Screening for TGFB Signaling Regulator expression in human HCC

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Verlaufskontrolle des Fibrosegrades nach Lebertransplantation – Histologie und Transiente Elastografie mittels FibroScan im direkten Vergleich

To biopsy or not to biopsy: Evaluation of a large German cohort of patients with unclear hepatopathy and negative for viral hepatitis A, B, or C

Tharun, L

Leberbiopsien bei Verdacht auf Primär Sklerosierender Cholangitis (PSC) – hilfreich oder unnötig?

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Thasler, WE

An algorithm that predicts the viability and the yield of isolated human hepatocytes from surgical remnant tissues

Novel in vitro model for combined effects of irinotecan and free fatty acids on hepatocellular lipid accumulation and inflammation

Protective effects of Iso-Alpha Acids (IAA) on hepatic steatosis, inflammation and fibrosis

Anti-fibrogenic effects of sylimarin vary significantly in human hepatic stellate cells from different donors

CYP2E1 is a central mediator for the synergistic effects of alcohol and free fatty acids on hepatocellular steatosis and inflammation

Thavamani, A

The Serum Reponse Factor (SRF) is involved in the transcriptional upregulation of the functional p53 inhibitor MDM 4 in hepatocellular carcinoma

Thiel, C

Kontrollierter Prozess zur Generierung einer azellularisierten Lebermatrix

Influence of Carbon Chain Length on Formation and Composition of Triglycerides in Free Fatty Acid- induced Steatosis

Thiel, K

Kontrollierter Prozess zur Generierung einer azellularisierten Lebermatrix

Thimme, R

Efficacy and safety of transjugular intrahepatic portosystemic shunt in patients with hepatocellular carcinoma: a single center experience

Restoration of Hepatitis C virus-specific CD8+ T-cell responses in patients undergoing IFN-free antiviral therapy

Dominance of cytolytic effector functions in hepatitis B virus-specific CD8+ T cell and NK cell mediated antiviral efficacy using hepatitis B virus infected hepatocytes overexpressing human sodium taurocholate cotransporting polypeptide

A protective HLA-B*27 restricted epitope contributes to viral control in chronic HCV infection despite presence of viral escape mutations and is characterized by a unique T cell phenotype

Comparison of different inhibitory pathways in hepatitis B virus-specific CD8+ T cell exhaustion

Thoens, C

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Thomann, S

Avidity and shear stress-linked anchoring to tumor endothelium: transfer the principles of leukocyte adhesion for tumor-specific drug delivery

Thorgeirsson, SS

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Tiedje, C

The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection

Tiegs, G

Maternal Liver Damage Programs Offspring Allergic Inflammation in Mice

An additional heme oxygenase-1 knockout increases systemic inflammation and fibrosis in MDR2 knockout mice

Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice

Identification of HO-1/CO-induced tumor protective genes in HCC

The limonoids TR4 and TR9 induce apoptosis in mouse and human hepatoma cell lines

Tihaa, L

Antifibrotic effects of CCN1/CYR61 in primary portal myofibroblasts through induction of reactive oxygen species and resulting apoptosis

Timm, J

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Decades after spontaneous HBsAg clearance the CD8+ T cell immune response is less vigorous compared to chronic hepatitis B viral infection

Tölken, R

Verlaufskontrolle des Fibrosegrades nach Lebertransplantation – Histologie und Transiente Elastografie mittels FibroScan im direkten Vergleich

Tönissen, H

Risk factors for acute renal impairment following orthotopic liver transplantation

Tony, HP

Higher frequency of peripheral CD3CXCR3 and CD4CXCR3 positive blood cells in HCV patients in context of bile acid retention

Tran, CW

NK cell activity promotes liver damage and chronic viral infection

Trautmann, T

TREM1-Defizienz begünstigt die vorzeitige Klärung einer Virushepatitis im Mausmodell

Trautwein, C

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Erhöhte miR-122 Serumkonzentration stellen einen Biomarker für einen Leberschaden bei kritisch kranken Patienten dar

Human keratin 8 variants predispose to acetaminophen hepatotoxicity

Hepatic stellate cell specific endoglin deletion modulates TGF-β signaling and aggravates liver fibrosis in two experimental models of murine liver injury

Optimization purity of isolated primary liver endothelial cells (LSEC) using adenoviral gene transfer

Die CREMα-abhängige T-Zellantwort hemmt Progression der chronischen Lebererkrankung und deren Komplikationen

Die RIP3-abhängige Nekroptose inhibiert die inflammatorische Hepatokarzinogenese durch eine Hemmung der Caspase-8- und JNK-abhängigen kompensatorischen Zellproliferation

Fehlen von gp130 in Hepatozyten verringert die Tumorlast in einem Modell der chemisch induzierten Leberkarzinogenese

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Protektive Wirkung des HGF/c-Met bei Acetaminophen induziertem Leberschaden durch Inhibierung von oxidativem Stress

β7-Integrins and MAdCAM-1 play an opposing role during the development of Non-alcoholic steatohepatitis (NASH)

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Hsp72 overexpression protects from acetaminophen and DDC-associated liver injury but enhances protein aggregation

Trebicka, J

Mas-Receptor Überexpression in (mREN2)27 Ratten nach Leberschädigung ist protektiv für die Fibrose und portale Hypertension

Die JAK2-Hemmung senkt den Pfortaderdruck in einem genetischen NASH-Modell der Ratte

Treckmann, J

Long-term maintenance of human liver tissue by ex-vivo perfusion of liver sections

Triller, N

Hepatitis C Virus modulates TNFα-induced chemokine production and enables EGF to induce chemokine production in its host cell

Trilling, M

The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection

Trippler, M

KIR2DL3+ NKG2A- Natural Killer Cells Protect People who Inject Drugs against Productive Hepatitis C Virus Infection

Interferon stimulated gene 15, a proviral factor in hepatitis C virus replication, is regulated by the Proteasome subunit alpha type-6

Trivedi, PJ

Virus Infection Of Hepatic Sinusoidal Endothelial Cells Regulates Hepatic T Cell Recruitment And Activation

Trojan, J

Severe 25-hydroxyvitamin D deficiency identifies HCC patients with a poor prognosis

Tsamo, AT

The limonoids TR4 and TR9 induce apoptosis in mouse and human hepatoma cell lines

Tschopp, O

MicroRNAs as Mediators in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Steatohepatitis

Tuma, S

Hepatic FATP4-deficiency causes alterations in lipid metabolism

Deficiency of group via Phospholipase A2 in OB/OB mice renders protection against hepatic steatosis by reduction of VLDL secretion and alteration of phospholipid fatty acid composition

Tunaru, S

Nachweis von funktionellen Autoantikörpern gegen den muskarinischen Acetylcholinrezeptor M3 (M3AchR) in Seren von Patienten mit autoimmunen Lebererkrankungen

Tural, C

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Uckert, W

T cells redirected by a chimeric antigen receptor efficiently control Hepatitis B Virus replication in an immunocompetent mouse model

Uerlings, R

Potential novel diagnostic applications of laser ablation inductively coupled plasma mass spectrometry in trace metal imaging of hepatic metal disorders

Ulrich, F

Multifocal β-catenin activated hepatocellular adenomas (HCA) with malignant transformation in hepatocellular carcinoma (HCC) after abuse of anabolic steroids

Gibt es prädiktive Parameter für das frühe HCC-Rezidiv nach Lebertransplantation?

Umgelter, A

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

HIV-1 infection impairs frequency and functionality of HBV-specific CD4 T cells in patients with chronic hepatitis B

Urban, S

Dominance of cytolytic effector functions in hepatitis B virus-specific CD8+ T cell and NK cell mediated antiviral efficacy using hepatitis B virus infected hepatocytes overexpressing human sodium taurocholate cotransporting polypeptide

Urbaniak, T

Hepatic differentiation of hiPSC in a 3D multicompartment bioreactor

Ureche, CI

Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

Uschner, F

Mas-Receptor Überexpression in (mREN2)27 Ratten nach Leberschädigung ist protektiv für die Fibrose und portale Hypertension

Uschner, FE

Die JAK2-Hemmung senkt den Pfortaderdruck in einem genetischen NASH-Modell der Ratte

Valletta, D

Expression and function of methylthioadenosine phosphorylase (MTAP) in activated hepatic stellate

Keratinocyte growth factor inhibits hepatic inflammation and fibrosis in murine models of hepatic injury

Expression and function of glucose transporter 1 (GLUT1) expression in activated hepatic stellate cells

van de Leur, E

Antifibrotic effects of CCN1/CYR61 in primary portal myofibroblasts through induction of reactive oxygen species and resulting apoptosis

Differential regulation of Id1 expression by TGF-β1 in HepG2 cells

van der Maaden, K

Expression of myelin auto-antigens and myelin altered peptide ligands in the liver in EAE mice models

Vargas Cardenas, D

Erhöhte miR-122 Serumkonzentration stellen einen Biomarker für einen Leberschaden bei kritisch kranken Patienten dar

Die RIP3-abhängige Nekroptose inhibiert die inflammatorische Hepatokarzinogenese durch eine Hemmung der Caspase-8- und JNK-abhängigen kompensatorischen Zellproliferation

Venturelli, S

Secondary resistances to measles virus (MeV)-based virotherapy

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Verdier, J

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Vinisko, R

Faldaprevir plus pegyliertes Interferon alpha-2a und Ribavirin (PR) bei Patienten mit HIV und Hepatitis C Genotyp (GT)-1 Koinfektion: End of Treatment Response (ETR) – Ergebnisse der Phase III Studie STARTVerso 4

Vogel, M

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Vogt, A

Die intratumorale Behandlung mit IL-2-exprimierenden DC inhibiert das Tumorwachstum von subkutanen HCC und steigert die Rekrutierung von regulatorischen T-Zellen im Tumorgewebe

Voigt, E

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

Volz, T

The expression profile of bile acid and cholesterol synthesis genes are affected by the binding of Hepatitis B Virus to its cellular receptor

Proliferation of hepatitis B virus infected human hepatocytes in humanized mice treated with the entry inhibitor Myrcludex-B induces strong cccDNA reduction and maintenance of cccDNA-free hepatocytes

Different antiviral effects induced by interferon or entecavir in HDV infected human-chimeric uPA/SCID mice determined by new intrahepatic qRT-PCR assay

Hemoxygenase-1 and its downstream product Biliverdin suppress HCV replication and provides hepatoprotective effects in humanized uPA/SCID mice

Vornlocher, HP

Toll-like receptor 3 activation mediates the expression of interferon and interferon stimulated genes during hepadnaviral replication in HBV-transgenic mice lacking the HBs-antigen

Vucur, M

Die RIP3-abhängige Nekroptose inhibiert die inflammatorische Hepatokarzinogenese durch eine Hemmung der Caspase-8- und JNK-abhängigen kompensatorischen Zellproliferation

Wagner, N

β7-Integrins and MAdCAM-1 play an opposing role during the development of Non-alcoholic steatohepatitis (NASH)

Waibel, M

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Waidmann, O

Single measurement of hemoglobin predicts outcome of HCC patients

Severe 25-hydroxyvitamin D deficiency identifies HCC patients with a poor prognosis

Waldburger, N

Multifocal β-catenin activated hepatocellular adenomas (HCA) with malignant transformation in hepatocellular carcinoma (HCC) after abuse of anabolic steroids

Walker, R

Tumor suppressive mechanisms in hepatocellular carcinoma through inhibition of IL-6 signaling

Wang, J

Protective role of Ursodeoxycholyl Lysophosphatidylethanolamide during hepatic ischemia and reperfusion injury in mice

Deficiency of group via Phospholipase A2 in OB/OB mice renders protection against hepatic steatosis by reduction of VLDL secretion and alteration of phospholipid fatty acid composition

Wang, XW

Tumor suppressive mechanisms in hepatocellular carcinoma through inhibition of IL-6 signaling

Wannhoff, A

Phospholipase A2 controls fatty acid uptake into liver cells in a pharmacologically-responsive way

Reduction of alkaline phosphatase levels improves survival in PSC patients independent of dominant stenosis

In PSC patients the influence of cholestasis and cholangitis on CA19 – 9 serum levels depends on FUT2/3 genotype

Wanninger, J

Geschlechtsspezifische Expression der hepatischen Mangan-Superoxiddismutase bei der nicht alkoholische Fettlebererkrankung (NAFLD)

Warth, A

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Weaver, CT

NK cell activity promotes liver damage and chronic viral infection

Weber, A

Comparison of transient elastography, 13C-Methacetin meta-bolism, and liver biopsy for evaluation of fibrosis in chronic hepatitis C infection

Computer assisted image analysis of hepatic collagen: ASSO-ciations to metavir staging, transient elastography and 13C methacetin metabolism in patients with chronic hepatitis C infection

Weber, S

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Weber, SN

Frequent PNPLA3 variant determines the fate of patients with chronic liver diseases: a Liver unit experience

Multiple quantitative trait locus modelling (MQM) of experimental liver fibrosis

Wedemeyer, H

Thrombozytenzahl, Albumin und Bilirubin identifizieren Patienten mit chronischer Hepatitis C Zirrhose mit hohem Risiko für ein Therapieversagen und schwerwiegende Nebenwirkungen während einer Triple-Therapie mit Boceprevir oder Telaprevir

The impact of adipokines hormones on HCV life-cycle

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Successful triple therapy of patients with chronic hepatitis C genotype 1 infection leads to significant improvement of non-invasive liver fibrosis tests

Wehmeyer, MH

Wirksamkeit und Sicherheit der Tripletherapie bei chronischer Hepatitis C Virusinfektion außerhalb kontrollierter Studien

Weichert, W

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Weiland, T

Secondary resistances to measles virus (MeV)-based virotherapy

Differentielle Induktion von Apotose und Therapie-induzierter Seneszenz (TIS) durch die beiden DNA-Methyltransferase Inhibitoren 5-Azacytidin und 5-Aza-2'-deoxycytidin

Weiler-Normann, C

Exzellentes Therapieansprechen und gute Verträglichkeit der immunsuppressiven Therapie bei älteren Patienten mit autoimmuner Hepatitis

Leberinfitrierende CD4 T Zellen bei der autoimmunen Hepatitis zeigen ein distinktes TH1 Profil

Gp210 als ein negativer prädiktiver Marker für den Verlauf der Primär Biliären Zirrhose (PBC)

Vitamin D deficiency in primary sclerosing cholangitis is related to histological fibrosis stage at the time of diagnosis

Weinmann, A

Feasibility and benefits of systemic second-line therapy in advanced hepatocellular carcinoma (HCC) – a retrospective analysis

Survival analysis of proposed BCLC B subgroups in hepatocellular carcinoma patients

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Risk factors for acute renal impairment following orthotopic liver transplantation

Weiskirchen, R

TGF-β1 modulates LPS-induced NLRP3 inflammasome activity

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Impact of soluble Endoglin on TGF-β1 mediated immediate early responses in HepG2 cells

Hepatic stellate cell specific endoglin deletion modulates TGF-β signaling and aggravates liver fibrosis in two experimental models of murine liver injury

Optimization purity of isolated primary liver endothelial cells (LSEC) using adenoviral gene transfer

Antifibrotic effects of CCN1/CYR61 in primary portal myofibroblasts through induction of reactive oxygen species and resulting apoptosis

Blockade of NLRP3 expression in primary hepatocytes by inhibitors of NF-κB signalling

Differential regulation of Id1 expression by TGF-β1 in HepG2 cells

Potential novel diagnostic applications of laser ablation inductively coupled plasma mass spectrometry in trace metal imaging of hepatic metal disorders

Weismüller, T

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Weiss, KH

Reduction of alkaline phosphatase levels improves survival in PSC patients independent of dominant stenosis

In PSC patients the influence of cholestasis and cholangitis on CA19 – 9 serum levels depends on FUT2/3 genotype

Weiss, T

Ischämie-Reperfusions vermittelter Schaden wird durch das Leberregenerations assoziiertes Protein ALR vermittelt

Weiss, TS

Geschlechtsspezifische Expression der hepatischen Mangan-Superoxiddismutase bei der nicht alkoholische Fettlebererkrankung (NAFLD)

Reduktion von Lipo-apoptose in Abhängigkeit der Lokalisation und Isoform des hepatoprotektiven Protein ALR

Palmitinsäure induzierter lipoxischer ER-Stress und Lipo-apoptose wird durch das hepatoprotektive Protein ALR vermindert

Welker, MW

Gibt es prädiktive Parameter für das frühe HCC-Rezidiv nach Lebertransplantation?

Welte, T

Alpha-1-Antitrypsin inhibits acute liver failure in mice

Weng, HL

Decreased phosphorylated Smad3 at linker site predicts poor prognosis of patients with cholangiocarcinoma

Wenzel, J

Quality of HBsAg-specific immune memory: response to hepatitis-B-revaccination in adolescents 10 – 15 years after immunization in infancy

Wenzel, JJ

Decline in Hepatitis E Virus (HEV) Antibody Prevalence in Southeastern Germany, 1996 – 2011

Werner, CR

Wirksamkeit und Sicherheit der Triple-Therapie mit Telaprevir bei 102 Patienten mit Hepatitis C, Genotyp 1: SVR 12 Daten

Epidemiologische Entwicklung und Genotypisierung von Patienten mit einer chronischer Hepatitis B in Deutschland: Hinweise für einen Rückgang des Genotyp A zu Gunsten des Genotyp D

Verträglichkeit und Wirksamkeit einer Telaprevir Triple-Therapie der Hepatitis C, Genotyp 1 nach Lebertransplantation – SVR 24 Daten

Werner, JM

Ribavirin Pretreatment Improves the IFN-γ Response of Natural Killer Cells to IFN-based Therapy of Hepatitis C Virus Infection

Monocytes Affect Natural Killer cell Antiviral IFN-γ Production in HCV Infection via Inflammasome-mediated IL-18 Secretion

Westhaus, S

Endogenous oxidized LDL levels predict treatment response in interferon-based therapy of chronic hepatitis C

Wiegand, SB

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Wiegard, C

TREM1-Defizienz begünstigt die vorzeitige Klärung einer Virushepatitis im Mausmodell

Vitamin D deficiency in primary sclerosing cholangitis is related to histological fibrosis stage at the time of diagnosis

Wieland, M

TGF-β2 in Chronic Liver Disease (CLD) and Hepatocellular Carcinoma (HCC)

Wietzke-Braun, P

Nebenwirkungsspektrum während und nach erfolgreicher HCV Triple-Therapie nach Leberlebendtransplantation

Differentialdiagnose des hiliären Cholangiocarcinoms (Klatskin-Tumor): Extrapankreatische Form einer IgG4-positiven Autoimmunpankreatitis – Ein Fallbericht

Langzeitüberleben mit TIPS

Korrelation der nicht-invasiven ShearWave-Elastografie und der sonographisch assistierten Leberbiopsie bei der Bestimmung des Leberfibrosgrades

Wild, P

Glucose transporter isoform 1 (GLUT1) expression determines tumorigenicity of melanoma cells and their potential to form hepatic metastasis

Wilkens, L

Notch signaling is required for cholangiocarcinoma progression and is enhanced by inactivation of p53 in vivo

Wilson, M

Primary but not secondary biliary acids inhibit hepatitis D virus entry into human hepatoma cells expressing the sodium-taurocholate cotransporting polypeptide

Wingerter, L

Offspring of high fat diet fed dams develop hepatic steatosis

Winkler, J

Nup155 is linked to the p53 pathway in HCC

Winkler, S

Hepatogenic differentiated murine mesenchymal stem cells display functional qualities of perivenous and/or periportal hepatocytes

Hepatocytic Differentiated Mesenchymal Stem Cells for Translational Research in the Pig

Wirth, T

Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses

Wissniowski, T

Additive anti-Tumor Response to the Rabbit VX2 Hepatoma by Combined Radio Frequency Ablation and Toll like Receptor 9 Stimulation

Woerns, MA

Survival analysis of proposed BCLC B subgroups in hepatocellular carcinoma patients

Wohlfahrt, J

Beneficial effects on weight gain, hepatic steatosis and expression of lipogenic target genes in a murine obesity model after IL-1 type cytokine inactivation

Wolf, S

Intercellular communication of macrophages and hepatocytes and its impact on macrophage differentiation and activation

Woller, N

Resectable transgenic tumor models in mice for biliary cancers

Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

Wolter, F

Phänotypische und funktionelle Analyse von natürlichen Killer T (NKT)-Zellen bei HIV-Patienten mit einer akuten Hepatitis C

Die HIV-assoziierte Dysregulation der NKp46 Expression auf NK Zellen könnte die Suszeptibilität für HCV und deren Verlauf beeinflussen

Wolter, K

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

Wönne, EC

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Wörns, MA

Feasibility and benefits of systemic second-line therapy in advanced hepatocellular carcinoma (HCC) – a retrospective analysis

Bedeutung des Caspase 8-Homologs cFLIP bei der metabolischen Leberschädigung

Wranke, A

Quantification of Large, Middle and Small Hepatitis B virus (HBV) surface protein (HBsAg) fractions in patients with Hepatitis Delta

Wright, MC

Hepatic trans-differentiation of pancreatic hepatocyte-progenitor cells (B-13) in a 3D high-density culture system

Wruck, C

Protektive Wirkung des HGF/c-Met bei Acetaminophen induziertem Leberschaden durch Inhibierung von oxidativem Stress

Wuestefeld, T

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

Alpha-1-Antitrypsin inhibits acute liver failure in mice

Development of shRNA transgenic mice for preclinical studies of the MKK4 regeneration kinase

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

Wulf, JH

Identification of HO-1/CO-induced tumor protective genes in HCC

Wurst, W

ABCB4-defiziente Mäuse zeigen depressives und ängstliches Verhalten

Wutka, A

Capsaicin impairs carcinogenesis of human intra- and extrahepatic cholangiocarcinoma cells

Xu, HC

NK cell activity promotes liver damage and chronic viral infection

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

Youssef, R

Comparison of transient elastography, 13C-Methacetin meta-bolism, and liver biopsy for evaluation of fibrosis in chronic hepatitis C infection

Computer assisted image analysis of hepatic collagen: ASSO-ciations to metavir staging, transient elastography and 13C methacetin metabolism in patients with chronic hepatitis C infection

Yun-Han, L

Effective depletion of hepatic cancer stem-like cells by NF-kB mediated inhibiton of histone deacetylases

Yurttas, C

Different 5-FC prodrug application regimes result in different oncolytic efficiencies

Zahner, D

Signaling pathways involved in carcinogenesis in a double hit mouse model of cholangiopathy and hepatitis B virus

Zeilinger, K

Hepatic trans-differentiation of pancreatic hepatocyte-progenitor cells (B-13) in a 3D high-density culture system

Comparison of the response of primary rat and human hepatocytes to ethanol exposition in a miniaturized three-dimensional (3D) multi-compartment bioreactor system

Hepatic differentiation of hiPSC in a 3D multicompartment bioreactor

Zellmer, S

Development of an in vitro co-culture system to assess the DILI-related potential of drugs

Integrierte metabolische und räumlich-zeitliche Modellierung des Ammoniak-Stoffwechsels während der Leber-Schädigung und -Regeneration

Zender, L

Multiplex in vivo RNAi screening instructs combination therapies to increase the therapeutic efficacy of the multikinase inhibitor sorafenib

Negative Selection In Vivo RNAi Screening Identifies a Ribosomal Protein As A New Therapeutic Target In Liver Cancer

Alpha-1-Antitrypsin inhibits acute liver failure in mice

In vivo RNAi screen for new tumor suppressor genes in Hepatocellular Carcinoma

Development of shRNA transgenic mice for preclinical studies of the MKK4 regeneration kinase

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes

Zenouzi, R

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Zeuzem, S

Efficacy and safety of Telaprevir in patients with hepatitis C genotype 1 infection: The German Telaprevir early access program

Safety of add on Interferon-alpha-2a in hepatitis B patients receiving effective nucleos(t)de therapy: Interim results from the German multicenter PADD-ON trial

Severe 25-hydroxyvitamin D deficiency identifies HCC patients with a poor prognosis

Zhang, K

Correlation of fulminant hepatitis B and escape mutations in the 2nd loop of the HBsAg a-determinant

Zhao, G

Synergism between Jnk1 and Jnk2 is a sine qua non condition for hepatic protection against toxicity

Hematopoietic cells-derived Jnk1 drives hepatic injury and hepatocellular carcinoma in IKKγ/NEMO-deleted livers

Zhou, Q

Human keratin 8 variants predispose to acetaminophen hepatotoxicity

Zimmer, V

Der Simplified AIH Score – Kriterium zur Einleitung einer Immunsuppression bei Patienten mit Primär Sklerosierender Cholangitis: Ergebnisse einer deutschen Multicenter Studie

Intrahepatic cholestasis-associated ATP8B1 variation underlying protracted cholestatic course of acute hepatitis E virus infection

Zimmermann, A

The MAPKAP kinase 2 controls IL-10 expression and protects from liver injury upon cytomegalovirus infection

Potential novel diagnostic applications of laser ablation inductively coupled plasma mass spectrometry in trace metal imaging of hepatic metal disorders

Zimmermann, HM

Caspase-8 acts as a tumor suppressor in chemically induced hepatocarcinogenesis in mice

Zimmermann, HW

Virus Infection Of Hepatic Sinusoidal Endothelial Cells Regulates Hepatic T Cell Recruitment And Activation

Zimmermann, T

Programmed liver biopsies after orthotopic liver transplantation predict non-alcoholic steatohepatitis during a 5-year follow up

Risk factors for acute renal impairment following orthotopic liver transplantation

Zinngrebe, H

Bedeutung des Caspase 8-Homologs cFLIP bei der metabolischen Leberschädigung

Zitzmann, A

Quality of HBsAg-specific immune memory: response to hepatitis-B-revaccination in adolescents 10 – 15 years after immunization in infancy

Zucknick, M

Deleted in Malignant Brain Tumors 1 (DMBT1) is differentially expressed in cholangiocarcinogenesis and shows influence on patient survival

Zucman-Rossi, J

A p19(Arf) and Aurka mediated G2/M arrest restricts oncogenic transformation of p53 deficient hepatocytes