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Int Arch Otorhinolaryngol 2013; 17(02): 218-221
DOI: 10.7162/S1809-97772013000200017
Case Report
Thieme Publicações Ltda Rio de Janeiro, Brazil

Chondro-osseous respiratory epithelial adenomatoid hamartoma of the nasal cavity

Faysal Fedda
1   M.D. (Resident).
,
Fouad Boulos
2   M.D. (Assistant Professor).
,
Alain Sabri
3   M.D. (Associate Professor).
› Author Affiliations
Further Information

Publication History

24 May 2011

25 June 2011

Publication Date:
09 January 2014 (online)

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Summary

Introduction: Chondro-osseous respiratory epithelial adenomatoid hamartoma (COREAH) is a benign lesion of the nose and sinuses that is extremely rare, with only 2 cases reported in the literature to date.

Case report: We present herein the third reported case of COREAH, in a 38-year-old woman who presented with left nasal obstruction and a mass in her left nasal cavity. The mass was completely resected endoscopically. Microscopic examination showed hamartomatous proliferation of respiratory-type glands with mucinous metaplasia admixed with numerous spicules of mature bone, characteristic of COREAH.

Conclusion: COREAH is a benign hamartomatous proliferation of respiratory epithelium, submucosal glands, and chondro-osseous mesenchyme. The clinical differential diagnoses for such lesions include glandular hamartoma, inflammatory polyp, inverted papilloma, and low-grade sinonasal adenocarcinoma. Recognition of this lesion as benign despite its potentially worrisome radiographic appearance is important to avoid an unnecessarily radical surgical procedure.

Keywords

nasal cavity - hamartoma - nasal polyps
 

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