Successful salvage of failed post-sarcoma excision reconstruction and exposed alloplastic mesh with an anterolateral thigh flap

The salvage of a patient with a failing chest reconstruction can be far more challenging than the primary reconstruction itself. Free flaps have an important role for this and it is usually standard practice to remove and replace any previously exposed alloplastic implants at the time that definitive soft tissue cover is achieved. This is proposed to reduce the risk of future infection due to colonization of the implant [1]. Unfortunately, removal of alloplastic material is not always possible [2].

A 69-year-old patient was referred to our unit with a low-grade myofibroblastic sarcoma affecting his anterior chest wall ([Fig. 1]). Excision of the tumor was performed by a joint team of cardiothoracic and general surgeons. An acellular porcine dermal implant (Permacol; Medtronic Public Ltd., Minneapolis, MN, USA) was used to cover the pericardium. Over this implant an omental flap was placed and resurfaced with a split thickness skin graft.

Fig. 1. Preoperative photographs showing the extent of the soft tissue sarcoma in our patient’s chest wall.

Three days after this operation, spontaneous coughing caused evisceration of abdominal contents. The failed omental flap required immediate debridement and the acellular porcine dermal implant was removed. The resulting defect was covered with a topical negative pressure (TNP) dressing.

Four days later, the patient had to be taken back to theatre due to malfunctioning of the TNP system and further evisceration. On that same night, he eviscerated in to the wound for the third time. It was decided then to take him back to theatre for a revisional mesh repair of this abdominal and chest wall defect, using a polypropylene mesh (Prolene; Ethicon Inc., Somerville, NJ, USA), covered by TNP dressings.

Re-exploration and definitive soft tissue cover were undertaken 1 week later by a plastic surgery team. At that point, the polypropylene mesh was found completely adhered to mediastinal contents, and exchange of this implant was considered unfeasible ([Fig. 2]). A two-perforator, 16×25 cm free anterolateral thigh flap was raised and anastomosed to the internal thoracic artery and vein to resurface the wound and cover the exposed polypropylene mesh.

Fig. 2. (A) Picture showing the state of the polypropylene mesh by the time soft tissue covering was intended, adhered to mediastinal contents. (B) The utilized anterolateral thigh flap being raised is also shown

Final histological diagnosis confirmed excision with adequate margins and no postoperative radiotherapy or chemotherapy was required [3]. At his 1-year follow-up appointment the patient did not show signs of recurrence or any signs of infection clinically and on magnetic resonance imaging scans ([Fig. 3]).

Fig. 3. Postoperative pictures 6 months after the final surgical intervention, fully healed and not showing any signs of infection.

Even though it is ideal to exchange any exposed material by the time definitive cover is achieved, sometimes, due to the complexity of the case this is not possible. The previously exposed case intends to demonstrate the salvage of the situation with a free flap can be a feasible option.

Publication History

Received: 05 June 2018

Accepted: 12 September 2018

Article published online:
28 March 2022

• REFERENCES

• 1 Birolini C, de Miranda JS, Utiyama EM. et al. A retrospective review and observations over a 16-year clinical experience on the surgical treatment of chronic mesh infection. What about replacing a synthetic mesh on the infected surgical field?. Hernia 2015; 19: 239-46
• 2 Meagher H, Clarke Moloney M, Grace PA. Conservative management of mesh-site infection in hernia repair surgery: a case series. Hernia 2015; 19: 231-7
• 3 Dangoor A, Seddon B, Gerrand C. et al. UK guidelines for the management of soft tissue sarcomas. Clin Sarcoma Res 2016; 6: 20