Background The use of acellular dermal matrix (ADM) in implant-based immediate breast reconstruction
has been increasing. The current ADMs available for breast reconstruction are offered
as aseptic or sterile. No published studies have compared aseptic and sterile ADM
in implant-based immediate breast reconstruction. The authors performed a retrospective
study to evaluate the outcomes of aseptic versus sterile ADM in implant-based immediate
breast reconstruction.
Methods Implant-based immediate breast reconstructions with ADM conducted between April
2013 and January 2016 were included. The patients were divided into 2 groups: the
aseptic ADM (AlloDerm) group and the sterile ADM (MegaDerm) group. Archived records
were reviewed for demographic data and postoperative complication types and frequencies.
The complications included were infection, flap necrosis, capsular contracture, seroma,
hematoma, and explantation for any cause.
Results Twenty patients were reconstructed with aseptic ADM, and 68 patients with sterile
ADM. Rates of infection (15.0% vs. 10.3%), flap necrosis (5.0% vs. 7.4%), capsular
contracture (20.0% vs. 14.7%), seroma (10.0% vs. 14.7%), hematoma (0% vs. 1.5%), and
explantation (10.0% vs. 8.8%) were not significantly different in the 2 groups.
Conclusions Sterile ADM did not provide better results regarding infectious complications than
aseptic ADM in implant-based immediate breast reconstruction.
Keywords
Breast implants - Acellular dermis - Mammaplasty
