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DOI: 10.5999/aps.2016.43.5.466
A Simple, Reliable, and Inexpensive Intraoperative External Expansion System for Enhanced Autologous Structural Fat Grafting
The first two authors contributed equally to this work.
External volume expansion of the recipient site by suction has been proposed as a way of improving fat graft survival. The objective of this study was to present an innovative and simple intraoperative external expansion system to enhance small-volume autologous fat grafting (40–80 mL) and to discuss its background and its mechanism of action. In this system, expansion is performed using a complete vacuum delivery system known as the Kiwi VAC-6000M with a PalmPump (Clinical Innovations). The recipient site is rapidly expanded intraoperatively 10 times for 30 seconds each with a negative pressure of up to 550 mm Hg before autologous fat injection. During this repetitive stimulation, the tissues become grossly expanded, developing macroscopic swelling that regresses slowly over the course of hours following the cessation of the stimulus. The system sets various mechanisms in motion, including scar release, mechanical stimulation, edema, ischemia, and inflammation, which provide an environment conducive for cell proliferation and angiogenesis. In order to maintain the graft construct in its expansive state, all patients are encouraged postoperatively to use the Kiwi three times daily for one minute per session over the course of three days. The handling of this system is simple for both the patients and the surgeon. Satisfactory clinical outcomes have been achieved without significant complications.
This article was presented at the International Federation for Adipose Therapeutics and Science in Amsterdam, Holland, November 13th through 16th, 2014; and at the Seventh International Conference on Regenerative Surgery in Rome, Italy, December 10th through 12th, 2015.
Publication History
Received: 25 November 2015
Accepted: 29 March 2016
Article published online:
20 April 2022
© 2016. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonCommercial License, permitting unrestricted noncommercial use, distribution, and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes. (https://creativecommons.org/licenses/by-nc/4.0/)
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REFERENCES
- 1 Strong AL, Cederna PS, Rubin JP. et al. The current state of fat grafting: a review of harvesting, processing, and injection techniques. Plast Reconstr Surg 2015; 136: 897-912
- 2 Heit YI, Lancerotto L, Mesteri I. et al. External volume expansion increases subcutaneous thickness, cell proliferation, and vascular remodeling in a murine model. Plast Reconstr Surg 2012; 130: 541-547
- 3 Lancerotto L, Chin MS, Freniere B. et al. Mechanisms of action of external volume expansion devices. Plast Reconstr Surg 2013; 132: 569-578
- 4 Khouri RK, Rigotti G, Cardoso E. et al. Megavolume autologous fat transfer: part II. Practice and techniques. Plast Reconstr Surg 2014; 133: 1369-1377
- 5 Khouri RK, Eisenmann-Klein M, Cardoso E. et al. Brava and autologous fat transfer is a safe and effective breast augmentation alternative: results of a 6-year, 81-patient, prospective multicenter study. Plast Reconstr Surg 2012; 129: 1173-1187
- 6 Del Vecchio DA, Bucky LP. Breast augmentation using preexpansion and autologous fat transplantation: a clinical radiographic study. Plast Reconstr Surg 2011; 127: 2441-2450
- 7 Lujan-Hernandez J, Lancerotto L, Nabzdyk C. et al. Induction of adipogenesis by external volume expansion. Plast Reconstr Surg 2016; 137: 122-131
- 8 Lee JW, Han YS, Kim SR. et al. A rabbit model of fat graft recipient site preconditioning using external negative pressure. Arch Plast Surg 2015; 42: 150-158
- 9 Khouri RK, Rigotti G, Khouri Jr RK. et al. Tissue-engineered breast reconstruction with Brava-assisted fat grafting: a 7-year, 488-patient, multicenter experience. Plast Reconstr Surg 2015; 135: 643-658
- 10 Chin MS, Ogawa R, Lancerotto L. et al. In vivo acceleration of skin growth using a servo-controlled stretching device. Tissue Eng Part C Methods 2010; 16: 397-405