Primary lung cancer metastatic to the breast: case report of a patient in remission

ABSTRACT

While lung carcinoma is the most common of the malignant tumors, primary lung tumors metastatic to the breast are rare and the prognosis is poor. We report a case of a Brazilian, 65- year-old, black, female patient with no family history of breast or lung cancer. During physical gynecological examination, she presented with a palpable nodule in the outer quadrant of the right breast. Based on X-ray, CT, PET-CT and immunohistochemistry investigation, a diagnosis of primary tumor metastatic lung to breast was made. The patient was referred for setorectomy and bi-lobectomy, combined with chemotherapy. She was in remission from November 2012 until December 2018. Given the poor prognosis related to the disease, the evolution presented is surprising.

RESUMO

Embora o carcinoma pulmonar seja o mais comum dos tumores malignos, os tumores primários do pulmão metastáticos da mama são raros e o prognóstico é ruim. Relatamos um caso de uma brasileira, 65 anos, negra, do sexo feminino, sem histórico familiar de câncer de mama ou de pulmão. Durante o exame físico ginecológico, apresentou nódulo palpável no quadrante externo da mama direita. Com base na radiografia, tomografia computadorizada, PET-CT e investigação imunohistoquímica, foi feito o diagnóstico de tumor metastático primário do pulmão à mama. A paciente foi encaminhada para setorectomia e bilobectomia, combinada com quimioterapia. Ela estava em remissão de novembro de 2012 a dezembro de 2018. Dado o mau prognóstico relacionado à doença, a evolução apresentada é surpreendente.

Keywords:

Non-small-cell lung carcinoma - Neoplasm metastasis - Case report - Metastasis to breast.

Descritores:

Carcinoma pulmonar de não pequenas células - Metástase neoplásica - Relato de caso - Metástase da mama.

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