Mandibular advancement devices in obstructive sleep apnea: an updated review

Izabella Paola Manetta; Dominik Ettlin; Pedro Mayoral Sanz; Isabel Rocha; Miguel Meira e Cruz

doi:10.5935/1984-0063.20210032

Sleep Science, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Sleep Sci 2022; 15(S 02): 398-405
DOI: 10.5935/1984-0063.20210032

REVIEWS

Mandibular advancement devices in obstructive sleep apnea: an updated review

Izabella Paola Manetta

¹Department of Otolaryngology Pontificia, Universidade Católica de Campinas, - Campinas - São Paulo - Brazil.

,

Dominik Ettlin

²University of Zurich, Center of Dental Medicine - Zurich - Zurich - Switzerland.

³Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Berne, Berne, Switzerland.

,

Pedro Mayoral Sanz

⁴Catholic University of Murcia, Dental Sleep Medicine - Murcia - Murcia - Spain.

,

Isabel Rocha

⁵Cardiovascular Autonomic Function Lab, Centro Cardiovascular da Universidade de Lisboa, Lisbon School of Medicine, Lisbon, Portugal.

,

Miguel Meira e Cruz

⁶Sleep Unit, Centro Cardiovascular da Universidade de Lisboa, Lisbon School of Medicine, Lisbon, Portugal.

⁷Neuroimune Pain Interface Lab, Faculdade São Leopoldo Mandic, Campinas, São Paulo, Brazil.

⁸International Center of Clinical Sleep Medicine and Research, Escola Bahiana de Medicina e Saúde Pública, Salvador - Bahia, Brazil.

› Institutsangaben

Abstract

ABSTRACT

Obstructive sleep apnea (OSA) is the most prevalent sleep-disordered breathing in the adult population and if untreated remains a significant cause of morbidity and mortality. Continuous positive airway pressure (CPAP) therapy is still the gold standard treatment for OSA, but patient acceptance and adherence are often poor due to a multitude of factors, thereby compromising treatment success. Mandibular advancement devices (MADs) have been proposed not only as a first line therapy for symptomatic snoring patients, but also for those suﬀering from mild to moderate OSA, or those who refuse or do not tolerate CPAP. Yet, improved understanding of MAD regarding design, construction, and mechanisms of action is an important requirement to successfully implement MAD as a therapeutic tool. Therefore, the main focus of this paper is to focus on the general concepts and mechanisms of action of MAD, while highlighting important characteristics in the context of their use as a viable and effective treatment option for OSA patients.

Keywords:

Sleep Apnea - Obstructive - Mandibular Advancement - Occlusal Splints

Volltext

Referenzen

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