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DOI: 10.5935/1806-6054.20190008
2018 in review: gynecologic cancer insights
2018 em revisão: insights sobre câncer ginecológicoAutoren
Financial support: none to declare.
ABSTRACT
Gynecologic cancers constitute an important burden of disease around the world. Estimates from GLOBOCAN 2018 reveals approximately 1,247,300 incident casesand 596,000 related deaths of cancers of the uterine cervix, corpus uteri, and ovarian, annually around the world. In 2018 lots of promising results to improve disease control have been presented at international gynecological cancer meetings. The current review highlights some of the top gynecologic cancer news of 2018, including the new standard of care for BRCAmutant ovarian cancer patients with maintenance olaparib in first line, benefit of bevacizumab rechallenge for relapsed ovarian cancer patients, and the unexpected results of worse overall survival with minimally invasive surgery in early cervical cancer, among others.
RESUMO
Os tumores ginecológicos constituem um verdadeiro fardo à saúde feminina mundialmente. Estimativas do GLOBOCAN 2018 demonstram cerca de 1.247.300 casos e 596.000 mortes anualmente relacionadas aos tumores ginecológicos. Em 2018 foram apresentados trabalhos importantes sobre o manejo destes tumores nos principais congressos internacionais. Esse artigo de revisão destaca alguns destes trabalhos como a manutenção de olaparibe em primeira linha para as pacientes com câncer de ovário e mutação de BRCA, o benefício da re-exposição ao bevacizumabe para pacientes com câncer de ovário recidivado (platino sensível), os resultados inesperados da cirurgia minimamente invasiva em câncer de colo uterino inicial, dentre outros.
Publikationsverlauf
Eingereicht: 25. Dezember 2018
Angenommen: 26. Dezember 2018
Artikel online veröffentlicht:
07. März 2025
© 2022. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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