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CC BY-NC-ND 4.0 · World J Nucl Med 2021; 20(03): 324-326
DOI: 10.4103/wjnm.wjnm_35_21
Interesting Cases

Somatostatin-receptor avidity of pancreatic neuroendocrine tumor thrombus in porto-caval venous systems on 99mTc-Octreotide and posttherapeutic 177Lu-DOTA-TATE scans

Mahasti Amoui
Department of Nuclear Medicine, School of Medicine, Shahid Beheshti University of Medical sciences, Tehran, Iran
,
Reyhane Ahmadi
1   Department of Nuclear Medicine and Molecular Imaging, Farshchian Heart Center, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
,
Mohsen Qutbi
Department of Nuclear Medicine, School of Medicine, Shahid Beheshti University of Medical sciences, Tehran, Iran
,
Isa Neshandar Asli
Department of Nuclear Medicine, School of Medicine, Shahid Beheshti University of Medical sciences, Tehran, Iran
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Abstract

A 62-year-old woman with a history of abdominal pain presented with multiple hepatic lesions and dilatation of portal, splenic and superior mesenteric veins on the magnetic resonance imaging referred for a 99mTc-octreotide scan. Accordingly, similar octreotide-avid lesions were found as well as an uptake in the epigastric region conforming to the anatomy of the portocaval venous system, compatible with a tumor thrombosis. Then, the patient underwent two cycles of therapy with 177Lu-DOTA-TATE, on that the same appearance was observed. The uptake in the tumor thrombus remained somewhat unchanged, but clinically, a significant improvement of the intractable ascites was achieved.

Keywords

177Lu-DOTA-TATE - 99mTc-Octreotide - pancreatic neuroendocrine tumor - somatostatin-receptor - tumor thrombosis

Financial support and sponsorship

Nil.




Publikationsverlauf

Eingereicht: 16. März 2021

Angenommen: 24. Mai 2021

Artikel online veröffentlicht:
24. März 2022

© 2021. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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